DE2960503D1 - Novel androstadienes, processes for their preparation and pharmaceutical compositions containing them - Google Patents

Novel androstadienes, processes for their preparation and pharmaceutical compositions containing them

Info

Publication number
DE2960503D1
DE2960503D1 DE7979200088T DE2960503T DE2960503D1 DE 2960503 D1 DE2960503 D1 DE 2960503D1 DE 7979200088 T DE7979200088 T DE 7979200088T DE 2960503 T DE2960503 T DE 2960503T DE 2960503 D1 DE2960503 D1 DE 2960503D1
Authority
DE
Germany
Prior art keywords
androstadienes
novel
processes
preparation
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7979200088T
Other languages
English (en)
Inventor
Michael J Green
Robert Tiberi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scherico Ltd
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherico Ltd filed Critical Scherico Ltd
Application granted granted Critical
Publication of DE2960503D1 publication Critical patent/DE2960503D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • C07J71/0015Oxiranes at position 9(11)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/003Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE7979200088T 1978-02-27 1979-02-21 Novel androstadienes, processes for their preparation and pharmaceutical compositions containing them Expired DE2960503D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/881,217 US4183924A (en) 1978-02-27 1978-02-27 17α-Chloro-17β-hydrocarbonsulfinyl-1,4-androstadienes and the corresponding 17β-hydrocarbonsulfonyl derivatives and their use as anti-acne agents

Publications (1)

Publication Number Publication Date
DE2960503D1 true DE2960503D1 (en) 1981-10-29

Family

ID=25378014

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7979200088T Expired DE2960503D1 (en) 1978-02-27 1979-02-21 Novel androstadienes, processes for their preparation and pharmaceutical compositions containing them

Country Status (14)

Country Link
US (1) US4183924A (de)
EP (1) EP0003863B1 (de)
JP (1) JPS54122265A (de)
AT (1) ATA138979A (de)
AU (1) AU524089B2 (de)
DE (1) DE2960503D1 (de)
DK (1) DK77179A (de)
FI (1) FI790609A (de)
GR (1) GR73569B (de)
HU (1) HU180096B (de)
IL (1) IL56728A (de)
NO (1) NO790620L (de)
PT (1) PT69270A (de)
ZA (1) ZA79756B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4252733A (en) * 1980-03-31 1981-02-24 E. R. Squibb & Sons, Inc. 17-Substituted sulfonyl-16,16-disubstituted androstenes
US4342702A (en) * 1981-05-18 1982-08-03 The Upjohn Company Metallated halogenated acetylene corticoid synthesis
US4481144A (en) * 1984-02-03 1984-11-06 E. R. Squibb & Sons, Inc. 17-Substituted thia-17-alkyl(or alkenyl or alkynyl)androstenes
US4529548A (en) * 1984-05-07 1985-07-16 E. R. Squibb & Sons, Inc. 17β-(substituted thio)androstenes
US5981473A (en) * 1996-09-13 1999-11-09 Clemson University Composition and method for treating acne
US6221847B1 (en) 1996-09-13 2001-04-24 Clemson University Composition and method for treating bacterial infection

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2806041A (en) * 1955-10-25 1957-09-10 Searle & Co 17-alkylsulfonyl and 17-alkylsulfinyl substitution products of 4-androsten-3-one
US2999101A (en) * 1959-08-13 1961-09-05 Searle & Co 11-oxygenated 17-alkylsulfinyl- and 17-alkylsulfonylandrost-4-en-3-ones
US4091036A (en) * 1977-05-12 1978-05-23 E. R. Squibb & Sons, Inc. 17-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16 α, 17 α-b]naphthalenes and derivatives

Also Published As

Publication number Publication date
AU4450379A (en) 1979-09-06
EP0003863B1 (de) 1981-07-22
PT69270A (en) 1979-03-01
US4183924A (en) 1980-01-15
EP0003863A1 (de) 1979-09-05
ZA79756B (en) 1980-06-25
IL56728A0 (en) 1979-05-31
HU180096B (en) 1983-01-28
NO790620L (no) 1979-08-28
GR73569B (de) 1984-05-19
AU524089B2 (en) 1982-09-02
ATA138979A (de) 1982-11-15
IL56728A (en) 1981-11-30
DK77179A (da) 1979-08-28
JPS54122265A (en) 1979-09-21
FI790609A (fi) 1979-08-28

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee