DE2843719A1 - INSECTICIDE REDUCED TOXICITY - Google Patents

Description

OR. β ί RQ DIPL ...! NG. STAPF Attorney's file: 29 53fi ^DirL · ^IN3 "- ^^ 'T .- ^? ^ - ^SANDMA ' ^R

8 MCNCiScN CO · M A u ti ΓΗ KIRC H E RST R ^ 45

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October 6, 1978 Case 2-11377 / AFR 101 / +

Germany

Insecticide bait of reduced toxicity

The present invention relates to insecticidal compositions for use as bait, which are characterized in that they contain 0,0-dimethyl-S- (4-aza-6-chloro-2-oxo-benzoxazol-3-yl) -methyl- Thiophosphate, known under the name Azamethiphos, contains a small amount.

The compositions provided by the invention for use as bait are intended to destroy flying and / or crawling, annoying and / or harmful insects.

Among those so affected by these compositions flying insects are those belonging to the families Muscidae, Sarcophagidae and Tachinidae belonging to Diptera called.

Among the creeping insects that can also be affected are those belonging to the Blattidae families, Blattellidae and Blaberidae belonging Dictyoptera, the Isoptera belonging to the family Termitidae and the called Hymenoptera belonging to the family Formicidae.

The use of baits composed of a nutrient and an insecticide for Control of insects is known: however, so far, the insecticides useful in this type of composition have shown Means generally a high level of toxicity for warm-blooded animals, that is to say for humans and farm animals or pets.

Also, to be effective, these agents must be in fairly large amounts between 1 and 5% by weight Quantities to be incorporated into the bait.

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The following table lists the major insecticides commonly used in this way Means listed with their acute LD 50 on the rat, expressed in mg / kg:

Arprocarb: 104

Bendiocarb: 49

Chlorodecone: 127

Chlorpyrifos: 163

Diazinon: 450

Dichlorvos: 80

Dimethoate: 350

Dimetilan: 50

Dioxacarb: 70

Fenitrothion: 375

Fenthion: 252

Lindane: 88

Naled: 430

Perchlordecon: 312

Trichlorfon:

595 r)

This final insecticidal agent is used in amounts ranging up to 10% by weight of the bait can.

The applicant has now found that the insecticidal substance known under the name Azamethiphos can be used with remarkable effectiveness in baits in amounts of less than 1% . Since the toxicity of this substance is very low (acute LD 50 in rats: 1,180 mg / kg), insecticide compositions are obtained by combining them with a nutrient which are much less toxic to humans and farm animals or domestic animals.

The active ingredient Azamethiphos and various compositions such as powder powder, wettable powder, granules, emulsifiable liquids, liquid pastes and aerosols are known from U.S. Patent 3,886,2γ4 known. the very low toxicity of this substance and the high effectiveness of insecticide baits containing it in minimal quantities are not presupposed from the named patent

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watch.

The invention thus relates to insecticide compositions for use as bait containing an insect attractive nutrient and that under the Name Azamethiphos known 0,0-dimethyl-S- (4-aza-6-chloro-2-oxo-benzoxazol-3-yl) -methyl-thiophosphate contain.

The nutrient expediently consists of one or more preferably dehydrated components that from the group consisting of amino acid sources, carbohydrates and substances which contain at least one of these components are selected.

The amino acid source is selected from the biochemical class consisting of the protids, the means the actual amino acids, peptides and proteins.

The amino acids that the nutrient may contain include alanine, arginine, aspartic acid, Cysteine, cystine, glutamic acid, glycocolla, histidine, oxyproline, isoleucine, leucine, lysine, methionine, Called phenylalanine, proline, serine, threonine, tryptophan, tyrosine, and valine.

The peptides that can be used are natural or synthetic, by combining a proportion compounds formed by a limited number of amino acids. These include, for example, glutathione, which is found in yeast and intracellular building blocks of mammalian tissues, carnosine, found in the striated muscles of birds occurs, polyglutamic acid, which occurs in microorganisms, as well as various from incomplete hydrolysis called polypeptide chains derived from proteins.

Proteins are found in all tissues of living animals or plants. You will be through the union formed a large number of amino acids. These include, for example, Zein, Gliadin, Hordein, Arachin and the globulins found in plant seeds, myosin, actin and tropomyosin found in animal muscle fibers.

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come, serum albumin, lipoproteins, hemoglobin and fibrinogen, found in blood, ovalbumin, conalbumin, lysozyme and avidin found in eggs, casein and Lactoglobulin found in milk, collagen and elastin found in tendons and connective tissues, reticulin, found in skin and adipose tissues, as well as cornein, ichthyocol and elastoidin found in fish tissues occur called.

The proportion of the source of amino acids in the feed is generally between 2 and 100 wt -.% Feed, with the balance being optionally made of a non-protidischen nutrient.

The proportion of amino acid sources in the feed is preferably at least 10%, this proportion increasing relates to the weight of the feed.

The amino acid source is in the isolated state or in the raw state in its preferably dehydrated Medium of origin used.

Examples of raw amino acids and peptides are full or partial hydrolysates of vegetable origin or raw animal proteins.

The following are examples of proteins in their raw state and also, if appropriate, substances containing peptides The values in brackets represent the mean percentage of protids present:

A. Dried fruits . Dry apricots (5.2), dried dates (2.2), dried figs (3.1), dried peaches (3.0), dried pears (2.3), dried apples (3.0), dried Plums (2.3), dry grapes (2.3), almonds (18.6), peanuts (30.6), hazelnuts (12.7), walnuts (15.0) and cocoa (20.4).

B. dried vegetables . Dried cabbage (13.7), dried carrots (4.0), dried white beans (22.0), dried lentils (25.7), dried onions (10.1), dry peas (24.5) and dried potatoes (7.1).

C. Grain . Oat flakes (13.0), wheat flour (12.2), corn flour (9.2), rice flour (7.4), rye flour (11.0), soy

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flour (35.9), wheat germ (25.2), pearl barley (9.0) and dried wheat bread (9.8).

D. Dairy Products . Whole milk powder (25.8), skimmed milk powder (35.6), Emmental cheese (28.6), Limburg cheese (23.5), Parmesan cheese (36.3), Roquefort cheese (21.7) and powdered egg (48.2) .

E. Meat , beef meal (65), beef waste meal (72), horse meal (76), rabbit meal (74), mutton meal (68), pork meal (69), whale meal (78), poultry meal (73) and poultry waste meal (75).

F. Fish and crustaceans . Cod meal (63) »Tuna meal (82), crab meal (67) and herring meal (70).

G. Miscellaneous . Dry gelatine (85.6), bitter chocolate (5.5), milk chocolate (6.0), molasses (2.4), brewer's yeast (13.3), dry brewer's yeast (46.1) and dry mushrooms (40 ).

In the insecticide bait compositions of the invention the nutritional component, i.e. the amino acid source, preferably consists of a mixture of meat ■ flour and full or partial hydrolysates of proteins.

The non-protidic nutrient, if any, is selected from the group consisting of carbohydrates such as for example sucrose, maltose, lactose, glucose, fructose, galactose, raffinose, invert sugar, honey and Starch, as well as lipoids, are selected.

These carbohydrates and lipoids can naturally be found in those containing the raw amino acid source Substances in addition to various natural components such as celluloses or these substances in the Composition can be added.

In addition to the aforementioned carbohydrates that can be added to the composition, for example Low-protid foods of plant origin such as tapioca are indicated.

Examples of lipoids that can be added to the composition are butter, vegetable oils, Lard, tallow and fish oils indicated.

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The most important insecticide baits are those that contain a mixture of a preferably water-soluble carbohydrate and a source of amino acids. Such a bait particularly preferably contains at least 45% by weight amino acid source, this percentage being increased relates to the total weight of the composition.

If desired, the composition can comprise a binder such as a natural or synthetic glue and / or a dye or a pigment and / or a stabilizer.

If desired, the bait can also comprise an attractant and / or appetite agent, selected from those which are known to the person skilled in the art, for example natural or artificial flavors of cheese, meat and fruit, Amino acids, pollen extracts, thymol, skatole, indole, eugenol, Paraformaldehyde, hexamethylenetetramine, ammonium carbamate, aliphatic amines, papain, pancreatin, aliphatic Acids, vanillin, 3-chloro-3-methylbutene-1, 1-chloro-3-methylbutene-2 as well as straight-chain or branched alkenes with 19 to 24 carbon atoms, their ethylene bond after a carbon atom between the 7 and 11 positions is, for example, the following in the cis, trans or cis / trans configuration: 2-methyl-octadecene-9, Nonadecene-9, 2-methyl-nonadecene-9, eicose-9, 2-methyl-eicose-8, 8-methyl-eikosen-8, 10-methyl-eikosen-8, 2-methyl-eikosen-9, 10-methyl-eikosen-9, 19-methyl-eikosen-9, Heneikosen-9, 2-methyl-heneikosen-8, 8-methylheneikosen-8, 2-methyl-heneikosen-9, 10-methyl-heneikosen-9, 19-Methyl-heneikosen-9, 20-Methyl-heneikosen-9, 19-Aethyl-heneikosen-9, Dokosen-8, Dokosen-9, 2-Methyldokosen-8, 8-methyl-dokosen-8, 10-methyl-dokosen-8, 2-methyl-dokosen-9, lO-methyl-dokosen-9, 19-methyl-dokosen-9, 20-methyl-dokosen-9, 21-methyl-dokosen-9, 19-ethyl-dokosen-9, 20-Aethyl-dokosen-9, Trikosen-7, Trikosen-8, Trikosen-9, Trikosen-1O, Trikosen-11, 2-Methyltrikosen-8, 8-methyl-trikosen-8, 2-methyl-trikosen-9, 9-methyl-trikosen-9, 10-methyl-tricosen-9, 19-methyl-tricose

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kosen-9, 20-methyl-trikosen-9, 21-methyl-trikosen-9, 22-Methyl-tricosen-9, Tetrakosen-9 and Tetrakos en-10.

The attractant is preferably in the composition at a level of 0.1 to 1 percent based on the weight of the composition. Particularly this proportion is preferably between 0.1 and 0.5? o.

Among these attractants are the straight-chain alkenes, whose double bond is after the carbon atom in 8- or 9-position, and in particular the stereoisomers in the cis configuration such as cis-nonadecene-9, cis-eikosen-9, cis-Heneikosen-9, cis-Dokosen-9 and cis-Trikosen-9 in particular in the compositions according to the invention effective. The latter attractants include mixtures containing cis-tricots-9 and cis-tricoses-9 of special interest.

The compositions according to the invention are generally produced by simple mixing of the ingredients, however, it is preferable if they contain an insecticide for the better To distribute the insecticidal agent and the coloring agent in certain cases proceed as follows:

a) Mix the nutritional ingredients,

b) evaporate the insecticidal active ingredient and the dye in a sufficiently volatile solvent. or dissolve methylene chloride,

c) spray the solution b onto the mixture a and

d) evaporate all volatile solvent. The optimal particle size of the composition

varies with the type of insect you want to kill; in general, the particle size should be the finer the the smaller the insect the bait is intended for. This is preferably between 0.05 mm and 1 mm.

The bait can be in the form of a flowable powder or optionally with the aid of a binding agent agglomerated form, such as granules or tablets

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th, are available. He can also be in wet or dry, but preferably use dry. He then only owns a moisture content that does not exceed that resulting from the humidity of the ambient air.

The bait can also be fixed on an inert carrier or absorbed therein, this being inert Carriers made, for example, of paper, blotting paper, cardboard, plastic such as polystyrene, polyvinyl chloride, polyvinyl acetate and cellulose acetate, glass, pumice stone, broken marble or silica or silicate minerals can exist.

The following experiments demonstrate the importance of the compositions according to the invention.

TRIAL A

The following baits A-I, A-2 and A-3 (percentages by weight) are made:

TABLE I.

composition A-I A-2 A-3 Az amethiphos - - 4.75 Dirnetilan (a) 4.75 - - Fenitrothion (b) - 4.75 - Powdered sucrose 95.25 95.25 95.25 Calculated LD 50 (mg / kg) 1 053 7 895 24 842

(a) NjN-Dimethylcarbamic acid-1-dimethylcarbamyl-S-methylpyrazol-3-yl ester

(b) 0, O-dimethyl-O- (3-methyl-4-nitrophenyl) thiophosphate

These baits are placed in Petri dishes at a ratio of 0.25 grams per dish and the dishes are placed each in a cube-shaped room with an edge length of one meter with a glass side facing the daylight.

A hundred Musca domestica flies are released in each cube, and all six are noted Minutes the number of flies with dorsal decubitus. With permutation of the bait in the rooms one repeats

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this series of experiments six times in a row. The mean percentage of flies with dorsal decubitus will be for each bait is calculated from the sum of the repetitions. The results are summarized in the table below.

TABLE II "

Expired
Time in Wed
grooves A-I A-2 A-3 6th 10 6th 20th 12th 18th 19th 28 18th 24 26th 31. 24 26th 29 34 30th 27 32 36 36 28 34 37 42 30th 36 39 48 31 37 42 54 31 38 44 60 32 39 45

These results show that the baits with azamethiphos had a toxicity three times lower than that of Fenitrothion bait and a twenty-four times lower toxicity than dimetilan bait is significantly more effective than the latter own.

TRIAL B

The baits B-I to B-4 are made, the ones off a red blotting paper impregnated with a solution of sucrose and insecticide and after drying have the following composition:

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w-

TABLE III

composition BI B-2 B-3 B-4 Azamethiphos - 1.00 0.50 0.25 Dimetilane (a) 2.30 - - - ' Sucrose 45.65 46.30 46.50 46.60 [Red blotting paper 52.05 52.70 53.0- 53.15 Calculated LD 50 (mg / kg) 2 174 118,000 236,000 472,000

These baits are each normalized in a 28 m large, kept at a temperature of 25 ° C Room distributed. The baits are placed in a petri dish and slightly moistened with water.

100 Musca domestica flies are released into each room, and all fifteen are noted Minutes the number of flies with dorsal decubitus. Repeatedly permutating the bait across the room this series of experiments eight times. The mean number of flies with dorsal decubitus is made for each bait calculated from the sum of the repetitions. The results are summarized in the table below.

TABLE IV "

Expired
Time in Wed
grooves BI B-2 B-3 B-4 15th . 27 29 31 27 30th 38 44 · 48 43 45 40 52 55 47 60 43 58 58 51 75 45 60 60 52 90 48 63 62 53 120 50 65 64 54

The results of these experiments show that a bait according to the invention such as baits B-2, B-3 and B-4 against the insects is at least as effective as a prior art bait B-I, although the last

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is 54 to 217 times more toxic than those according to the invention Bait.

It can also be seen that the reduction in the content of azamethiphos reduces the effectiveness of the inventive Bait not affected.

TRIAL C

Bait is prepared as defined in the previous experiment under the designation B-2.

These baits are used for a period of 4 months put into use, during which their moisture is regularly maintained.

At the end of the 4 months, tests are carried out in cube-shaped rooms, as indicated in experiment A, to compare these baits with freshly made and moistened ones. The results are in the following Table summarized.

TABLE V

- Expired
Tent in Wed
grooves B-2
For 4 months
moisturizes B-2
Freshly made
and moisturizes 15th 20th 26th 30th 37 42 45 54 57 60 69 72

These results show that the inventive Bait still excellent after 4 months of use despite the moist condition in which it was kept Possess effectiveness. The invention thus enables the production of baits with long-lasting Effect.

TRIAL D

'Put the following baits D-I to D-7 through intimate mixing of the ingredients (values in percent by weight) as a fine powder:

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TABLE VI

composition D-I D-2 D-3 D-4 D-5 D-6 D-7 Sucrose 98.75 98.75 98.75 98.75 98.75 98.75 98.75 Red dye 0.80 0.80 0.80 0.80 0.80 0.80 0.80 cis-tricots-9 0.20 0.20 0.20 0.20 0.20 0.20 0.20 Azamethiphos - - - - - - 0.25 Jodfenphos (c) 0.25 - - - - - - Methoxychlor (d) - 0.25 - - - - - Fenchlorphos (e) - - 0.25 - - - - iVIalathion (f) - - - 0.25 - - - Natural Pyrethrins (g) - - - - 0.25 - - Tetramethrin (h) - - - - - 0.25 -

(c) 0- (2,5-dichloro-4-iodophenyl) -0,0-dimethyl thiophosphate (LD 50 = 2100 mg / kg)

(d) 2,2-bis (4-methoxyphenyl) -1,1,1-trichloroethane (LD 50 = 6000 mg / kg)

(e) 0- (2,4,5-trichlorophenyl) -0, O-dimethyl thiophosphate (LD 50 = 1740 mg / kg)

(f) S- (1,2-diethoxycarbonylethyl) -0, O-dimethyl-dithiophosphate (LD 50 = 2800 mg / kg)

(g) Mixture of the cinerolonyl, jasmolonyl and pyrethrolonyl chrysanthemates and pyrethrates

(LD 50 = 584 to 900 mg / kg)
(h) 3,4,5, ö-Tetrahydrophthalimidomethyl-chrysanthemat (LD 50 = 4,000 mg / kg)

These baits are each applied by means of a polyvinyl acetate-based glue to the entire inner surface of the lower Glued to the bottom of a cylindrical polystyrene box with a diameter of 12.5 cm and a height of 7 cm.

In the upper part of the cylinder, cut three openings

p
openings of 10 cm each.

The thus constructed apparatus is a one meter from each other in a bath maintained at a temperature of ⁰ 27/28 C and a relative humidity of about 50,

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- AS-

40 m room.

180 flies of the species Musca domestica are released into the room, and every fifteen minutes the number increases dead flies are recorded in the immediate vicinity of and in each device.

The procedure is repeated 7 times with the respective permutation of the position of the devices.

The overall results of the test group are summarized in the table below (number of dead flies per test).

TABLE VII

Expired
Time in Wed
grooves 15th D-I D-2 D-3 D-4 D-5 D-6 D-7 C. 30th 3.1 3.0 6.5 1.8 3.3 0.4 7.5 φ
hO 45 4.4 4.6 8.3 4.1 4.6 0.8 15.8 H Φ
AH
COH 60 4.6 5.3 9.1 4.4 5.1 1.3 21.9 N En
-P 90 6.1 6.0 10.2 5.1 5.8 2.2 25.2 CO Φ
CQ -P L20 7.2 7.1 11.1 5.6 8.3 4.7 33.9 Φ O
Ü-P Number of dead
Flying in
Inside everyone
contraption
at the end of the test 9.0 9.0 12.3 6.8 9.4 5.8 38.6 1.2 1.3 1.8 0.9 2.3 1.6 26.0

The results of these tests show that the insecticidal effectiveness is still very good when you the content of azamethiphos in the bait is reduced to a value that is only 0.25%.

If, instead of Azamethiphos, other insecticides known for their low toxicity are used in the same concentration of 0.25%, the result will not be the same, although all baits contain two strong attractants such as cis-Tricosen-9 and a red dye.

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TRY

The following baits E-I to E-7 are put through intimate mixing of the ingredients (values in percent by weight) as a fine powder:

TABLE VIII

composition EGG E-2 E-3 E-4 E-5 E-6 E-7 Sucrose 20.0 20.0 20.0 20.0 20.0 20.0 20.0 Beef meal 61.5 61.5 61.5 51.5 61.5 61.5 62.0 Protid Composition C j) 6.0 6.0 6.0 6.0 6.0 6.0 6.0 Caramel 5.0 5.0 5.0 5.0 5.0 5.0 5.0 Calcium orbinate 0.5 0.5 0.5 0.5 0.5 0.5 0.5 Calcium ilicate 5.0 5.0 5.0 5.0 5.0 5.0 5.0 cis-tricots-9 0.2 0.2 0.2 0.2 0.2 0.2 0.2 Red dye 0.8 0.8 0.8 0.8 0.8 0.8 0.8 Azamethiphos - - - - - - 0.5 Jodfenphos (c) 1.0 - - - - - - Methoxychlor (d) - 1.0 - - - - - Fenchlorphos (e) - - 1.0 - - - - Malathion (noun) - - - 1.0 - - - Fenitrothion (b) - - - - 1.0 - - DDAB (k) - - - - - 1.0 -

(j) Mixture consisting of chicken proteins and vegetable protein hydrolyzate, the latter being short-chain Contains peptides and most of the amino acids found in vegetable protein substances.

(k) Abbreviation for S- (4-Aza-2-oxo-benzoxazol-3-yl) -methyl-O, 0-diethyl dithiophosphate (LD 50 over 5000 mg / kg).

These baits are each applied to a 9 x 9 cm polystyrene plate using a polyvinyl acetate-based glue glued- The weight of the bait glued in this way is approximately two grams each each on the bottom of a 5 cm high, square (10 χ 10 cm) black cardboard box with two elongated

ρ
Openings of 11 cm each are placed in its upper side.

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The thus constructed apparatus is a one meter from each other in a 26/27 at a temperature of ⁰ C and. 40 m room kept at a relative humidity of about 50.

250 flies of the species Musca dornestica are found in the The room is released and every fifteen minutes the number of dead flies in the immediate vicinity of each device is recorded. as well as in these.

This procedure is repeated seven times with the respective permutation of the position of the devices.

• The overall results of the test group are in the summarized below (mean number of dead flies per test).

TABLE IX

Total number
dead flier Elapsed time
in minutes EGG E-2 E-3 E-4 E-5 E-6 E-7 15th
30th
60 0.5
10.2
13.0 1.2
2.0
2.0 0
1.7
7.0 4.2
6.5
11.5 8.0
18.7
25.5 2.0
7.7
10.7 54.0
77.5
90.7 Number of dead flies
inside everyone before
direction at the end of the test 7.1 0 2.7 6.2 16.3 6.5 77.6

TRY F

The following baits F-I to F-6 are put through intimately Mix the ingredients (¥ ¥ ¥ utes in percent by weight) as a fine powder:

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TABLE X

composition F-I F-2 F-3 F-4 F-5 F-6 Sucrose 20.0 20.0 20.0 20.0 20.0 20.0 Beef meal 61.5 61.5 61.5 61.5 61.5 61.5 Prοtidzus nursing setting (j) 6.0 6.0- 6.0 6.0 6.0 6.0 Caramel 5.0 5.0 5.0 5.0 5.0 5.0 Calcium orb inat 0.5 0.5 0.5 0.5 0.5 0.5 Calcium silicate 5.0 5.0 5.0 5.0 5.0 5.0 cis-tricots-9 0.2 0.2 0.2 0.2 0.2 0.2 Red dye 0.8 0.8 0.8 0.8 0.8 0.8 Azamethiphos - - - -. - 1.0 barbaryl (m) 1.0 - - - - -. rühanite (η) - 1.0. - - - - paled (ο) - - 1.0 - - - Butonate (ρ) - - - 1.0 - - Profenofos (q) - - - - 1.0 -

(m) N-methylcarbamic acid naphth-1-yl ester (LD 50 = 850 mg / kg).

(n) Isobornyl thiocyanoacetate (LD 50 = 1600 mg / kg) (ο) 0- (1,2-dibromo-2,2-dichloroethyl) -0, O-dimethyl phosphate

(LD 50 = 430 mg / kg).
(p) 0, O-dimethyl- (l-butyryloxy-2,2,2-trichloroethyl) -phos-

phonate (LD 50 = 1350 mg / kg).
(q) 0- (4-Bromo-2-chlorophenyl) -0-ethyl-S-isopropyl thiophosphate (LD 50 = 360 mg / kg).

The procedure is then as in experiment E using 190 flies per test and repeating six times the way of working.

The overall results of the test group are summarized in the table below (number of dead flies per test).

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TABLE XI

Total number
dead flies Elapsed time
in minutes F-I F-2 F-3 F-4 F-5 F-6 15th
30th
60 4.8
7.0
8.2 1.9
1.9
1.9 20.5
23.8
26.4 14.4
18.8
20.9 12.5
17.3
21.1 48.6
62.7
83.2 Number of dead flies
inside everyone before
direction at the end of the test 7.4 0 20.1 18.1 14.5 75.7

The results of tests E and F show that azamethiphos in all cases has an effectiveness which is very clearly higher than that of the other insecticidal substances used of low or medium toxicity. This also applies if the azamethiphos content is reduced by half compared to the other insecticidal substances, as in experiment E. Attention should also be drawn to the exceptional position of Azamethiphos, which gives excellent insecticidal effectiveness, while DDAB (E-6), which belongs to the same family and whose chemical constitution differs only slightly from that of Azamethiphos, only one even at twice the concentration gives very poor effectiveness.

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Claims (18)

DR. BE RG nipi ..- iH0.-8TAPF υιΡ! ... · π>! - ?. c. : \ ννΛ ;;?: ■: ■ ':. ΰΛί; υ:. '. Α5Π 3MON-HEfSU · iviV.j £ iiKliii.Hf.iiST! 1.45 CLAIMS 1. Insecticide composition for use as bait ■ which contains a nutrient that is attractive to insects, characterized in that it contains 0,0-dimethyl-S- (4-aza-6-chloro-2-oxo-benz oxazol-3-yl) methyl thiophosphate [Azamethiphos]. 2. .. insecticide composition according to claim 1, characterized in that azamethiphos is the only insecticide substance is present. 3. Composition according to one of claims 1 and 2, characterized in that it contains about 0.01 to 5% by weight Azamethiphos, these proportions being based on the total weight of the composition. 4. Composition according to claim 3, characterized in that indicates that the amount of azamethiphos contained therein is less than or equal to 1 wt .-%, calculated on the Total weight of the composition. 5. Composition according to claim 3, characterized in that the amount contained therein azamethiphos is less than or equal to 0.25 wt%, calculated on the total weight of the composition. 6. Composition according to any one of claims 1 to 5, characterized in that the nutrient is selected from the group consisting of amino acid sources, carbohydrates and at least one of these constituents containing substances is selected. 7 · Composition according to claim 6, characterized in that the amino acid source from the group consisting of is selected from amino acids, peptides, proteins and mixtures of these ingredients. 8. Composition according to any one of claims 1 to 7, " characterized in that the amino acid source is from a mixture of meat meals and full or partial hydrolysates of proteins. 9. Composition according to one of claims 1 to 8, characterized in that the nutrient consists of at least 909815/1021 consists of a carbohydrate. 10. Composition according to one of claims 1 to 9, characterized in that the nutrient consists of a mixture consists of at least one amino acid source and at least one carbohydrate. 11. Composition according to claim 10, characterized in that it is at least 45 weight percent amino acid source which percentage is calculated based on the total weight of the composition. 12. The composition according to any one of claims 1 to 11, characterized in that it has a proportion of 0.1 to Contains 1 percent, based on the weight of the composition, of an attractant consisting of the group consisting of from straight-chain or branched alkenes with 19 to 24 carbon atoms, whose ethylene bond to one carbon atom is between the 7- and 11-position, and mixtures of at least two such alkenes is. 13. Composition according to claim 12, characterized in that · the attractant contains cis-tricose-9 or represents. 14. Composition according to any one of claims 1 to 13, characterized in that it is in the form of particles the mean size of which fluctuates between 0.05 mm and 1 mm. 15. Composition according to claim 14, characterized in that that it is in the form of a flowable powder. 16. Composition according to claim 14, characterized in that it is in agglomerated form. 17 · Composition according to any one of claims 1 to 16, characterized in that it is on an inert carrier is fixed. 18. Use of 0,0-dimethyl-S- (4-aza-6-chloro-2-oxobenzoxazol-3-yl) -methyl-thiophosphate as an insecticide in insecticidal compositions for use as bait. 909815/1021