DE2347111A1 - Multiple test strip for chemical solution analysis - has several test strip elements which are combined into one multiple test strip - Google Patents
Multiple test strip for chemical solution analysis - has several test strip elements which are combined into one multiple test stripInfo
- Publication number
- DE2347111A1 DE2347111A1 DE19732347111 DE2347111A DE2347111A1 DE 2347111 A1 DE2347111 A1 DE 2347111A1 DE 19732347111 DE19732347111 DE 19732347111 DE 2347111 A DE2347111 A DE 2347111A DE 2347111 A1 DE2347111 A1 DE 2347111A1
- Authority
- DE
- Germany
- Prior art keywords
- test strip
- multiple test
- combined
- chemical solution
- potassium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/521—Single-layer analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
- G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
Description
Dr. rer. nat. Wolfgang Ludwig 2ooo Norderstedt 3, Breslauer Str. 29, Postfach 1349Dr. rer. nat. Wolfgang Ludwig 2ooo Norderstedt 3, Breslauer Str. 29, PO Box 1349
Mehrfach-Teststreifen und Verfahren zur Analyse chemischer Lösungen. Multiple test strips and methods for analyzing chemical solutions .
Aus der DT-OS 21 52 099 ist ein Teststreifen und Tesisbreifenverfahren zur Analyse chemischer Lösungen bekannt. Die vorliegende Zusatzanmeldung zu diesem Teststreifen und Teststreifen-Verfahren betrifft einen Mehrfaeh-Teststreifen (1),(2),(3) und seine Anwendung zur gleichzeitigen analytischen Bestimmung mehrerer Substanzen in chemischen Lösungen.From DT-OS 21 52 099 is a test strip and test strip method known for the analysis of chemical solutions. The present additional application for this test strip and test strip method relates to a multiple test strip (1), (2), (3) and its simultaneous use analytical determination of several substances in chemical solutions.
Erfindungsgemäß wird dies erreicht durch Kombination mehrerer Teststreifen-Teile (1),(2); (1),(3) usw. gemäß der DT-OS 21 52 099, die neben- 'oder übereinander angeordnet sind und von denen jeder einzelne Teststreifen-Teil (1),(2); (1),(3) usvr. ein anderes Fällungsreagenz enthält, das mit jeder der zu bestimmenden Substanz je eine schwer- oder unlösliche Verbindung oder Bindung eingeht. According to the invention, this is achieved by combining several test strip parts (1), (2); (1), (3) etc. according to of DT-OS 21 52 099, which are arranged next to or on top of one another and of which each individual test strip part (1), (2); (1), (3) etc. another precipitation reagent contains that enters into a sparingly or insoluble compound or bond with each of the substances to be determined.
Weiterhin betrifft die vorliegende Zusatzanmeldung ein Mehrfach-Teststreifen-Verfahren zur gleichzeitigen Mehrfachanalyse chemischer Lösungen nach dem Fällungsverfahren, bei denKin den Teststreifen-Teilen (1),(2); (1),(3) usw. nach dem Kontakt mit der zu untersuchenden chemischen Lösung erfolgten Trübungen zur Lichtabsorption bzw. zur Lichtstreuung benutzt werden und die LichtSchwächung des durch die Teststreifen-Teile (1),(2); (1),(3) usw. fallenden Lichtes bzw. des von den Teststreifen-Teilen (1),(2); (1)»(3) usw. reflektierten Lichtes als Maß für die zu . bestimmenden Substanzgehalte verwendet wird.Furthermore, the present additional application relates to a multiple test strip method for simultaneous multiple analysis chemical solutions according to the precipitation process, in the case of the test strip parts (1), (2); (1), (3) etc. after contact with the chemical solution to be investigated, cloudiness for light absorption or for Light scattering can be used and the light attenuation of the through the test strip parts (1), (2); (1), (3) etc. light falling or that of the test strip parts (1), (2); (1) »(3) etc. reflected light as a measure of the too. determining substance content is used.
Vorzugsweise wird der Mehrfach-Teststreifen in Form eines Doppel-Teststreifens (1),(2),(3) und seine Anwendung zur Bestimmung des Kalium-Natrium-Quotienten im Harn vorgeschlagen. Eine Bestimmung des Kalium-Natrium-Quotienten The multiple test strip in the form of a double test strip (1), (2), (3) and its use for determining the potassium-sodium quotient in urine is proposed. A determination of the potassium-sodium quotient
509813/0947509813/0947
im Harn ist insbesondere bei Herzpatienten and postopertiv wichtig zur Erkennung eines Hyperaldosteronismus.in the urine is particularly important in cardiac patients and postoperatively for the detection of hyperaldosteronism.
Mithilfe eines Doppel-Teststreifens (1),(2),(3) für Kalium- und Natrium-Analyse kann jeder niedergelassene Arzt oder sogar der Patient selbst eine einfache Schnellbestimmung durchführen. Vorteil der Kombination mehrerer Teststreifen-Teile (1),(2) und (1),(3) usw. ist die Möglichkeit, die verschiedenen Teststreifen-Teile (1),(2) und (1),(3) usw. aus der gleichen Charge herzustellen, sodaß Fehler durch Fremdeinflüsse wie Feuchtigkeit, Alterung usw. auf ein Minimum beschränkt werden. Die Genauigkeit der Analyse, insbesondere bei notwendiger Quotientenbildung, wird also erhöht.Using a double test strip (1), (2), (3) for potassium and sodium analysis can be done by any general practitioner or doctor even the patient himself can carry out a simple quick determination. Advantage of combining several test strip parts (1), (2) and (1), (3) etc. is the possibility to use the different test strip parts (1), (2) and (1), (3) etc. from the same batch, so that errors due to external influences such as moisture, aging, etc. Minimum. The accuracy of the analysis, especially when it is necessary to form a quotient, is thus elevated.
Als Beispiel sei die Bestimmung des Kalium-Natrium-Quotienten im Harn gebracht:The determination of the potassium-sodium quotient in urine is given as an example:
Auf einem substrierten Folienträger (1) von ca. 11 mm Breite und ca. 60 mm Länge werden im Abstand von ca. 1 mm zwei Schichten (2) und (3) von je ca. 5 mm Breite und ca. 40 mm Länge aufgebracht (Figur 1), sodaß eine 11 χ 20 mm große Fläche zum Halten des Folienträgers (1) mit Daumen und Zeigefinger unbeschichtet bleibt. Die Schicht (2) besteht aus Gelatine, die mit Natriumtetraphenylborat und einem Stabilisator gegen Zersetzung durch Bakterien z.B. Natriumsalizylat - versetzt ist. Die Schicht (2) dient dem quantitativen Nachweis von Kaliumionen.On a subbed film carrier (1) approx. 11 mm wide and approx. 60 mm long, approx. 1 mm Two layers (2) and (3) each approx. 5 mm wide and approx. 40 mm long are applied (Figure 1), so that an 11 χ 20 mm large area for holding the film carrier (1) with thumb and forefinger remains uncoated. The layer (2) consists of gelatin treated with sodium tetraphenylborate and a stabilizer against bacterial degradation e.g. Sodium salicylate - is added. The layer (2) is used for the quantitative detection of potassium ions.
Die zweite Schicht (3) besteht aus Gelatine, die mit Kaliumhexahydroxoantimonat und einem Stabilisator versetzt ist. Die Schicht (3) dient dem quantitativen Nachweis von Natriumionen.The second layer (3) consists of gelatin to which potassium hexahydroxoantimonate and a stabilizer are added is. Layer (3) is used for the quantitative detection of sodium ions.
Der Doppel-Teststreifen (1),(2),(3) wird in die zu untersuchende Harnprobe eine bestimmte Zeit lang, z.B. 5 Minuten, eingetaucht, wobei die Schichten (2) und (3) je eine definierte Harnmenge durch Quellen aufnehmen. Die Schicht (2) trübt sich dabei durch ausfallendes Kaliumtetraphenylborat und die Schicht (3) durch ausfallendes Natritrahexahydroxoantimonat. Das Verhältnis der beiden Trübungen ist ein Maß für den Kalium-Natrium-QuotientenThe double test strip (1), (2), (3) is immersed in the urine sample to be examined for a certain time, for example 5 minutes, the layers (2) and (3) each absorbing a defined amount of urine by swelling. Layer (2) is clouded by precipitating potassium tetraphenylborate and layer (3) by precipitating sodium hexahydroxoantimonate. The ratio of the two opacities is a measure of the potassium-sodium quotient
5098 13/09475098 13/0947
Claims (1)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2152099A DE2152099C3 (en) | 1971-10-19 | 1971-10-19 | Test strips and methods for analyzing chemical solutions |
DE19732347111 DE2347111A1 (en) | 1971-10-19 | 1973-09-19 | Multiple test strip for chemical solution analysis - has several test strip elements which are combined into one multiple test strip |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2152099A DE2152099C3 (en) | 1971-10-19 | 1971-10-19 | Test strips and methods for analyzing chemical solutions |
DE19732347111 DE2347111A1 (en) | 1971-10-19 | 1973-09-19 | Multiple test strip for chemical solution analysis - has several test strip elements which are combined into one multiple test strip |
Publications (1)
Publication Number | Publication Date |
---|---|
DE2347111A1 true DE2347111A1 (en) | 1975-03-27 |
Family
ID=25761903
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE2152099A Expired DE2152099C3 (en) | 1971-10-19 | 1971-10-19 | Test strips and methods for analyzing chemical solutions |
DE19732347111 Pending DE2347111A1 (en) | 1971-10-19 | 1973-09-19 | Multiple test strip for chemical solution analysis - has several test strip elements which are combined into one multiple test strip |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE2152099A Expired DE2152099C3 (en) | 1971-10-19 | 1971-10-19 | Test strips and methods for analyzing chemical solutions |
Country Status (1)
Country | Link |
---|---|
DE (2) | DE2152099C3 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4274832A (en) * | 1979-02-12 | 1981-06-23 | Eastman Kodak Company | Analytical element and method for analysis of multiple analytes |
DE4411661A1 (en) * | 1994-04-05 | 1995-10-12 | Schoettler Markus Dipl Geol | Multi-parameter video technical analysis process for fluid media |
DE4444533A1 (en) * | 1994-12-14 | 1996-06-27 | Juergen Lehmann | Test strips for detecting electrolytes in urine |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4260392A (en) * | 1978-07-07 | 1981-04-07 | Technicon Instruments Corporation | Method and apparatus for obtaining an aliquot of a liquid in a gel medium |
US4250257A (en) * | 1978-08-24 | 1981-02-10 | Technicon Instruments Corporation | Whole blood analyses in porous media |
EP0140886B1 (en) * | 1983-04-13 | 1988-09-07 | Crystal Diagnostic Systems, Inc. | Film badge for determining carbonyl compounds |
-
1971
- 1971-10-19 DE DE2152099A patent/DE2152099C3/en not_active Expired
-
1973
- 1973-09-19 DE DE19732347111 patent/DE2347111A1/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4274832A (en) * | 1979-02-12 | 1981-06-23 | Eastman Kodak Company | Analytical element and method for analysis of multiple analytes |
DE4411661A1 (en) * | 1994-04-05 | 1995-10-12 | Schoettler Markus Dipl Geol | Multi-parameter video technical analysis process for fluid media |
DE4444533A1 (en) * | 1994-12-14 | 1996-06-27 | Juergen Lehmann | Test strips for detecting electrolytes in urine |
Also Published As
Publication number | Publication date |
---|---|
DE2152099C3 (en) | 1975-03-13 |
DE2152099B2 (en) | 1974-05-22 |
DE2152099A1 (en) | 1973-05-03 |
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