DE1917393B

DE1917393B - N, N dimethyl 2 ethylbutyric acid amide as a fragrance

Info

Publication number: DE1917393B
Authority: DE
Inventors: Serge Vitry sur Seine VaI de Marne Tchehtcheff (Frankreich)
Original assignee: Rhone Poulenc SA
Current assignee: Rhone Poulenc SA

Claims

1 2

The present invention relates to the use and common organic solvents easily

of N, N-dimethyl-2-ethylbutyric acid amide as odor-soluble.

substance or flavoring agent for food. Cosmetics to achieve peppermint-like subsidence, in which it can be introduced as it Grades. 5 against the action of alkaline or acidic

We know the need for peppermint-like reagents as well as the action of light and also smells or flavors. They are very resistant to aging in odor.
compositions or in taste compositions- Because of these properties, these compositions can be used. In the odor-related products in the usual manner in perfumery, their peppermint-like scents impart a considerable freshness to soap products or cosmetics. In flavor care, in dentifrices and mouthwashes, in compositions, the peppermint-like hygienic products as well as in beverages, liqueur flavors are also irreplaceable, regardless of whether they are used, confectionery or medication. Its beverages, confectionery products or the amount used is practically the same as that of toothbrushes or mouthwashes, only 15 common peppermint oils, but it should of course be named for the most important uses. the desired smell and taste effects

So far, this peppermint-like smell and could be customized. It delivers particularly interesting ones

Taste only by using natural results for lotions for which a refreshing one

oils can be achieved. Although it is known that menthol effects are desired, for example for shaving

and has been in use for a long time, but this 20 water.

Due to its strength and aggressiveness, it can only be used with Das N, N-Dimethyl-2-ethylbutyric acid amide

Use caution. especially according to R. Lukes. J. Langthaler

The peppermint-like products are interesting and I. Cervena (coll. Czech. Chem. Comm., 25,

sante biological properties: p. 461 [I960]; Chem. Abst, 54, p. 11 974 [1960])

A certain Eupnean effect, slightly antiseptic 25 can be made. In the following example, the properties are however, a certain insect repellent written procedure is new and preferred, Effect and a slight calming effect in it is not the subject of the present registration insect bites. One finds the peppermint-like dung.

Products are therefore used in many preparations for pharmaceutical purposes. Example 1

table or hygienic use. 3 ° _{In a mixture of 130 cm} , _{an aqueous dirae} .

In the course of laboratory work, _{thylamine solutions with a content of 35O g of} diethyl

linÄ ° ^Γη Γ,? «V m ° t5 ÄÄ - ?? ·, κ u ^amine J ^{e liter} ^{and 25Ü} cm ^{3 of} ethyl ether are added

Mentioned [1906]) that the HN-Diathyl-2-atliylbutter- _{Bew (^} _s _r _{IMD under maintenance} e pose a temperature

acidic a faint odor reminiscent of that _{of O} o _c _mcm * 10 "-sodium hydroxide solution and then

of menthol reminded has :, and it st known that a solution of 135 _inncrha 35] _b of 15 minutes, g

if N, N-diethyl-2 2-dimethylpropionsaurearaid to _{add 2} -ethylbutyrylchloride in 250 cm of ethyl ether. Man

Has a peppermint odor. These products are however _still _hm _{3Q minutes iQ Be u} ^ _{obei the Tera.}

Laboratonumskurioataten stayed and were kept _pe temperature at 0 ⁰ C. The ether layer becomes

not used in the perfume separated and then over 25 g of potassium carbonate

It has now been found that the NN-DuneÜiyl- 40 _{tr (} _{after filtering and} evaporation of the ethyl

2-ethylbutyric acid amide as a perfume product and as _{ether is distilled 134 5 N} , N-dimethyl-2-ethyl-

Fragrance and as a flavoring for the food _{butyric acid} from (b.p., = 75 to 77 * C; yield:

Industry for the production of natural peppermint 94om

notes is usable. ^{l <>>} ' example ^

This product has a peppermint-like gel 45 aftershave

smell of a surprisingly natural character. It sorbitol 70% / ig 12g

does not have the aggressiveness of menthol, whereas propylene glycol does 14 g

it practically has its strength. Its grade is 10 s after the Glvcerin

Pouilot odor oriented towards peppermint and close to boric acid 20 e

that of Italomitcham peppermint varieties. 50 N N-dimethyl-2-ethylbutter-

It can therefore be used alone or in a mixture in product amide 10 g

those that have a peppermint-like smell of distilled (or perrautated) '

or taste. In compositions, water O s 1000 g

in which it is introduced, it creates a '"'" on the skin. , '"'" '"

pleasant fresh sensation. 55 B e 1 s ρ 1 e I 3

This product has also been found to be a perfume for dentifrices

Physiologically remarkably safe: Its clove oil 10

lethal dose 50 _{% / 0} (DL50) in the mouse is rose oil 5

490 mg / kg when administered intravenously and 900 mg / cinnamon oil, Ceylon 10

kg when administered orally. The animal experiments have 60 anisole 400

showed that it is for the cardio-vascular system, the N, N-dimethyl-2-ethylbutyric acid amide 575
respiratory system and the neurovegetative system This oil is tooth-tolerated _{in an amount of 3 ° / 00.} It has no irritating effect on pastes of the usual recipe used,
the skin or mucous membranes off.

It is therefore at least as useful as the 6 ₅ claim:

natural peppermint oils. Use of N, N-dimethyl-2-ethylbutter-

It is a colorless liquid that under a pressure acid amide as a fragrance or aromatizing agent

boils from 1 mm Hg at 54 to 58 ^{° C.} In water it is a means for food and cosmetics.