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Examples are presented of management systems that can be used to improve IPM practices and reduce soilborne diseases and nematodes by stimulating the antagonistic potential in both high-input agriculture and low-input sustainable production systems. Methods used to measure and characterize the antagonistic potential in soils will be discussed. Examples of biological enhancement techniques used to treat seed and/or planting material in both annual and perennial crops in tropical and temperate cropping systems will be shown.