DE112005003431A5 - Novel inhibitors of lysyl oxidase - Google Patents

Novel inhibitors of lysyl oxidase Download PDF

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Publication number
DE112005003431A5
DE112005003431A5 DE112005003431T DE112005003431T DE112005003431A5 DE 112005003431 A5 DE112005003431 A5 DE 112005003431A5 DE 112005003431 T DE112005003431 T DE 112005003431T DE 112005003431 T DE112005003431 T DE 112005003431T DE 112005003431 A5 DE112005003431 A5 DE 112005003431A5
Authority
DE
Germany
Prior art keywords
lysyl oxidase
novel inhibitors
inhibitors
novel
lysyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE112005003431T
Other languages
German (de)
Inventor
Elmar Reinhold Burchardt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Burchardt Elmar Reinhold Drdr
Original Assignee
Burchardt Elmar Reinhold Drdr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Burchardt Elmar Reinhold Drdr filed Critical Burchardt Elmar Reinhold Drdr
Publication of DE112005003431A5 publication Critical patent/DE112005003431A5/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Supercharger (AREA)
DE112005003431T 2004-11-22 2005-11-20 Novel inhibitors of lysyl oxidase Withdrawn DE112005003431A5 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004056226A DE102004056226A1 (en) 2004-11-22 2004-11-22 Novel inhibitors of lysyl oxidase
DE102004056226.1 2004-11-22
PCT/DE2005/002086 WO2006053555A2 (en) 2004-11-22 2005-11-20 Pyrazol-3-one and/or pyridazin-3-one derivatives used as inhibitors of lysyl oxidase

Publications (1)

Publication Number Publication Date
DE112005003431A5 true DE112005003431A5 (en) 2007-10-31

Family

ID=36177758

Family Applications (2)

Application Number Title Priority Date Filing Date
DE102004056226A Withdrawn DE102004056226A1 (en) 2004-11-22 2004-11-22 Novel inhibitors of lysyl oxidase
DE112005003431T Withdrawn DE112005003431A5 (en) 2004-11-22 2005-11-20 Novel inhibitors of lysyl oxidase

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE102004056226A Withdrawn DE102004056226A1 (en) 2004-11-22 2004-11-22 Novel inhibitors of lysyl oxidase

Country Status (3)

Country Link
EP (1) EP2089366A2 (en)
DE (2) DE102004056226A1 (en)
WO (1) WO2006053555A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3265456B1 (en) * 2015-03-06 2020-11-18 Pharmakea, Inc. Fluorinated lysyl oxidase-like 2 inhibitors and uses thereof
EP3265445B1 (en) 2015-03-06 2021-05-05 Pharmakea, Inc. Lysyl oxidase-like 2 inhibitors and uses thereof
WO2017003862A1 (en) * 2015-07-01 2017-01-05 Pharmakea, Inc. Lysyl oxidase-like 2 inhibitors and uses thereof
CA3013917A1 (en) 2016-02-09 2017-08-17 Pharmakea, Inc. Quinolinone lysyl oxidase-like 2 inhibitors and uses thereof
GB201602934D0 (en) 2016-02-19 2016-04-06 Cancer Res Inst Royal Compounds
MX2019002612A (en) 2016-09-07 2019-08-21 Pharmakea Inc Uses of a lysyl oxidase-like 2 inhibitor.
CA3036064A1 (en) 2016-09-07 2018-03-15 Pharmakea, Inc. Crystalline forms of a lysyl oxidase-like 2 inhibitor and methods of making
GB201809295D0 (en) 2018-06-06 2018-07-25 Institute Of Cancer Res Royal Cancer Hospital Lox inhibitors
CA3105599A1 (en) 2018-08-03 2020-02-06 Pharmaxis Ltd. Haloallylamine sulfone derivative inhibitors of lysyl oxidases and uses thereof
GB201818750D0 (en) 2018-11-16 2019-01-02 Institute Of Cancer Res Royal Cancer Hospital Lox inhibitors
US12018015B2 (en) 2021-06-18 2024-06-25 Aligos Therapeutics, Inc. Methods and compositions for targeting PD-L1

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5328913A (en) * 1992-12-11 1994-07-12 Duke University Minoxidil analogs as inhibitors of cell proliferation and lysyl hydroxylase
KR100657189B1 (en) * 1998-08-14 2006-12-14 니혼노야쿠가부시키가이샤 Pyridazinone derivatives and pharmaceutical compositions comprising the same
DE10216144A1 (en) * 2002-04-12 2003-11-06 Bayer Ag New 2-phenyl-4-phenoxy-3(2H)-pyridazinone derivatives useful as lysyl oxidase inhibitors for preventing or treating fibrotic diseases

Also Published As

Publication number Publication date
WO2006053555A3 (en) 2006-07-27
DE102004056226A1 (en) 2006-05-24
WO2006053555A2 (en) 2006-05-26
EP2089366A2 (en) 2009-08-19

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Legal Events

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8139 Disposal/non-payment of the annual fee