DE10326018A1 - Artificial iris diaphragm, as an implant in the eye, has a photo sensitizer to give color in UV light with a lower concentration in the center to match the behavior of a human pupil - Google Patents

Artificial iris diaphragm, as an implant in the eye, has a photo sensitizer to give color in UV light with a lower concentration in the center to match the behavior of a human pupil Download PDF

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Publication number
DE10326018A1
DE10326018A1 DE2003126018 DE10326018A DE10326018A1 DE 10326018 A1 DE10326018 A1 DE 10326018A1 DE 2003126018 DE2003126018 DE 2003126018 DE 10326018 A DE10326018 A DE 10326018A DE 10326018 A1 DE10326018 A1 DE 10326018A1
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Germany
Prior art keywords
center
iris diaphragm
light
diaphragm
eye
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE2003126018
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German (de)
Inventor
Jörn Dr. Kuchenbecker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otto Von Guericke Universitaet Magdeburg
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Otto Von Guericke Universitaet Magdeburg
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Publication date
Application filed by Otto Von Guericke Universitaet Magdeburg filed Critical Otto Von Guericke Universitaet Magdeburg
Priority to DE2003126018 priority Critical patent/DE10326018A1/en
Publication of DE10326018A1 publication Critical patent/DE10326018A1/en
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1602—Corrective lenses for use in addition to the natural lenses of the eyes or for pseudo-phakic eyes
    • A61F2/1605—Anterior chamber lenses for use in addition to the natural lenses of the eyes, e.g. iris fixated, iris floating
    • A61F2/1608—Iris fixated, e.g. by clamping iris tissue, by suturing to the iris
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/15—Implant having one or more holes, e.g. for nutrient transport, for facilitating handling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Prostheses (AREA)

Abstract

The artificial iris diaphragm (2), as an implant in the eye, colors in UV light and preferably blue, green or brown. The diaphragm body contains a film with a color photo sensitizer with a decreasing concentration towards the center. The diaphragm body has a center opening (2), positioning hole (4) and an iridectomy (5).

Description

Die Erfindung betrifft ein künstliches, in ein Auge implantierbares Iris-Diaphragma.The Invention relates to an artificial, Iris diaphragm implantable in one eye.

Derartige Iris-Diaphragmata sind aus DE 39 26 536 bekannt. Weitere implantierbare Iris-Implantate sind in der DE 198 50 807 , DE 100 10 683 , FR 2 696 340 , RU 2106832 oder US 6,280,469 beschrieben.Such iris diaphragms are out DE 39 26 536 known. Other implantable iris implants are in the DE 198 50 807 . DE 100 10 683 . FR 2 696 340 . RU 2106832 or US 6,280,469 described.

Nachteil dieser Implantate ist, dass sie entweder aus durchsichtigem Material, wie z.B. PMMA oder undurchsichtigem Material, wie z.B. eingefärbtes PMMA, beschaffen sind. Bei durchsichtigem Material ist die Blendung aufgrund eines vermehrten Lichteinfalls erhöht. Farbig eingefärbtes Material hat den Nachteil, dass sich vor allem die äußere Netzhaut nicht oder nur ungenügend untersuchen lässt, was z.B. bei Augen nach einer Verletzung ein deutlicher Nachteil ist.disadvantage of these implants is that they're either made of clear material, such as. PMMA or opaque material such as colored PMMA, are procured. With transparent material, the glare is due increased incidence of light. Colored material has the disadvantage that especially the outer retina is not or only insufficient lets examine what e.g. in eyes after an injury is a clear disadvantage.

Aufgabe der Erfindung ist es, bei Patienten, die ein künstliches Iris-Diaphragma implantiert bekommen, eine vermehrte Blendung zu verhindern und andererseits eine ausreichende augenärztliche Untersuchung zu ermöglichen.task the invention is in patients who have an artificial iris diaphragm implanted get to prevent increased glare and on the other hand an adequate ophthalmological examination to enable.

Gelöst wird diese Aufgabe durch ein phototropes künstliches Iris-Diaphragma, das sich bei UV-Lichteinfall farbig einfärbt.Is solved this task through a phototropic artificial iris diaphragm, that turns colored when exposed to UV light.

In besonderen Ausführungsformen der Erfindung können die photosensiblen Substanzen (Pyrane neben Spirooxazinen und/oder Fulgiden) vorzugsweise der Grundsubstanz aus PMMA oder oder einem faltbaren Material wie Acryl vor der Polymerisation beigemengt, auf dem Diaphragmakörper aufgebracht oder als Folie in das Diaphragma eingelassen werden. Die Folie könnte den Photosensibilisator in zum Zentrum abnehmender Konzentration enthalten, was zur Folge hätte, dass sich das Zentrum erst bei hoher Intensität der UV-Strahlung einfärbt, während sich die Peripherie schon bei geringer Intensität der UV-Strahlung einfärbt. Dies würde der Funktion der normalen Pupille am nähesten kommen. Das phototrope künstliche Iris-Diaphragma besteht vorzugsweise aus PMMA oder einem faltbarem Material, wie Weichacryl und färbt sich bei UV-Lichteinfall vorzugsweise blau, grün oder braun ein.In special embodiments of the invention the photosensitive substances (pyrans in addition to spirooxazines and / or Fulgiden) preferably the basic substance made of PMMA or or foldable material such as acrylic added before the polymerization, on the diaphragm body applied or embedded as a film in the diaphragm. The slide could the photosensitizer in decreasing concentration towards the center contain what would result that the center only colors itself with high intensity of UV radiation, while the periphery is already at low intensity of UV radiation Inking. This would come closest to the function of the normal pupil. The phototrope artificial Iris diaphragm is preferably made of PMMA or a foldable Material, such as soft acrylic and colors preferably blue, green or brown when exposed to UV light.

Die Erfindung wird im folgenden anhand von in der Zeichnung dargestellten Ausführungsbeispielen näher erläutert. Es zeigt:The Invention is illustrated below with reference to the drawing embodiments explained in more detail. It shows:

1 in Draufsicht ein erstes Ausführungsbeispiel; 1 in plan view a first embodiment;

2 in Seitenansicht das in 1 dargestellte erste Ausführungsbeispiel; 2 in side view the in 1 illustrated first embodiment;

3 in Draufsicht ein zweites Ausführungsbeispiel; 3 in plan view a second embodiment;

4 in Seitenansicht das in 3 dargestellte zweite Ausführungsbeispiel. 4 in side view the in 3 illustrated second embodiment.

Der Diaphragmakörper 1 mit Blendenöffnung 2 oder plus-brechenden Linsenkörper 3 und Iridektomie 3 färbt sich durch den Photosensibilisator bei UV-Lichteinfall vorzugsweise blau, grün oder braun ein.The diaphragm body 1 with aperture 2 or plus-refractive lens body 3 and iridectomy 3 preferably turns blue, green or brown due to the photosensitizer when exposed to UV light.

Der Photosensibilisator kann vorzugsweise auf eine Folie 6 aufgebracht werden, die in den Diaphragmakörper 1 eingelassen ist und den Photosensibilisator in zum Zentrum abnehmender Konzentration enthält.The photosensitizer can preferably be on a film 6 applied in the diaphragm body 1 is embedded and contains the photosensitizer in decreasing concentration towards the center.

Der Diaphragmakörper 1 ist mit einer oder mehren vorzugsweise kreisrunden Öffnungen 4 mit einer Größe von vorzugsweise 0,4 mm für eine bessere intraoperative Positionierung oder zusätzliche Fixation an der Lederhaut mittels Naht versehen.The diaphragm body 1 is with one or more preferably circular openings 4 with a size of preferably 0.4 mm for better intraoperative positioning or additional fixation to the dermis by means of a seam.

Der Diaphragmakörper 1 ist aus PMMA oder einem faltbarem Material wie Silikon, Hydrogel oder Acryl.The diaphragm body 1 is made of PMMA or a foldable material such as silicone, hydrogel or acrylic.

11
Diaphragmakörperdiaphragm body
22
Blendenöffnungaperture
33
Linsenkörperlens body
44
Positionierungslochpositioning hole
55
Iridektomieiridectomy
66
Folie mit Photosensibilisatorfoil with photosensitizer

Claims (5)

Künstliches, in ein Auge implantierbares phototropes Iris-Diaphragma, das sich bei UV-Lichteinfall farbig, vorzugsweise blau, grün oder braun einfärbt.artificial, phototropic iris diaphragm implantable in one eye colored when exposed to UV light, preferably blue, green or colored brown. Künstliches Iris-Diaphragma nach Anspruch 1, dadurch gekennzeichnet, dass der Diaphragmakörper einen farbigen Photosensibilisator enthält.artificial Iris diaphragm according to claim 1, characterized in that the diaphragm body contains a colored photosensitizer. Künstliches Iris-Diaphragma nach Anspruch 1 oder 2, dadurch gekennzeichnet, dass in den Diaphragmakörper eine Folie mit einem farbigen Photosensibilisator eingelassen ist.artificial Iris diaphragm according to claim 1 or 2, characterized in that in the diaphragm body a film with a colored photosensitizer is embedded. Künstliches Iris-Diaphragma nach Anspruch 3, dadurch gekennzeichnet, dass die Folie den Photosensibilisator in zum Zentrum des Diaphragmas abnehmender Konzentration enthält.Artificial iris diaphragm according to claim 3, characterized in that the film is the photo contains sensitizer in decreasing concentration towards the center of the diaphragm. Künstliches Iris-Diaphragma nach Anspruch 1, 2, 3 oder 4, dadurch gekennzeichnet, dass der Diaphragmakörper aus faltbarem Acryl besteht.artificial Iris diaphragm according to claim 1, 2, 3 or 4, characterized in that that the diaphragm body made of foldable acrylic.
DE2003126018 2003-06-05 2003-06-05 Artificial iris diaphragm, as an implant in the eye, has a photo sensitizer to give color in UV light with a lower concentration in the center to match the behavior of a human pupil Ceased DE10326018A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE2003126018 DE10326018A1 (en) 2003-06-05 2003-06-05 Artificial iris diaphragm, as an implant in the eye, has a photo sensitizer to give color in UV light with a lower concentration in the center to match the behavior of a human pupil

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DE2003126018 DE10326018A1 (en) 2003-06-05 2003-06-05 Artificial iris diaphragm, as an implant in the eye, has a photo sensitizer to give color in UV light with a lower concentration in the center to match the behavior of a human pupil

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2662054A1 (en) * 2012-05-07 2013-11-13 SNU R&DB Foundation Self-regulated artificial iris and method of fabricating the same

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3397023A (en) * 1964-12-16 1968-08-13 Polaroid Corp Light apertures
DE19850807A1 (en) * 1998-10-29 2000-05-04 Potsdamer Augenklinik Im Albre Artificial iris to simulate the human eye behavior as an implant or contact lens includes number of colored layers of biocompatible film incorporating elements for iris functions
DE10010683A1 (en) * 2000-03-04 2001-09-06 Morcher Gmbh Intraoccular lens with a transparent central region and a radially adjoining iris diaphragm for correction/cover of an aniridia is produced as a single unit

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3397023A (en) * 1964-12-16 1968-08-13 Polaroid Corp Light apertures
DE19850807A1 (en) * 1998-10-29 2000-05-04 Potsdamer Augenklinik Im Albre Artificial iris to simulate the human eye behavior as an implant or contact lens includes number of colored layers of biocompatible film incorporating elements for iris functions
DE10010683A1 (en) * 2000-03-04 2001-09-06 Morcher Gmbh Intraoccular lens with a transparent central region and a radially adjoining iris diaphragm for correction/cover of an aniridia is produced as a single unit

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2662054A1 (en) * 2012-05-07 2013-11-13 SNU R&DB Foundation Self-regulated artificial iris and method of fabricating the same

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