DE102012208376C5 - Satz und Verfahren zur Herstellung eines Radiopharmakons - Google Patents

Satz und Verfahren zur Herstellung eines Radiopharmakons Download PDF

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Publication number
DE102012208376C5
DE102012208376C5 DE102012208376.6A DE102012208376A DE102012208376C5 DE 102012208376 C5 DE102012208376 C5 DE 102012208376C5 DE 102012208376 A DE102012208376 A DE 102012208376A DE 102012208376 C5 DE102012208376 C5 DE 102012208376C5
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DE
Germany
Prior art keywords
sentence
cation exchange
solution
hydrochloric acid
hcl
Prior art date
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Active
Application number
DE102012208376.6A
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German (de)
English (en)
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DE102012208376B4 (de
DE102012208376A1 (de
Inventor
Dirk Müller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zentralklinik Bad Berka GmbH
Original Assignee
Zentralklinik Bad Berka GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48430785&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE102012208376(C5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zentralklinik Bad Berka GmbH filed Critical Zentralklinik Bad Berka GmbH
Priority to DE102012208376.6A priority Critical patent/DE102012208376C5/de
Priority to PCT/EP2013/059889 priority patent/WO2013171185A1/fr
Priority to AU2013261855A priority patent/AU2013261855B2/en
Priority to US14/402,032 priority patent/US20150098894A1/en
Priority to BR112014028601A priority patent/BR112014028601A2/pt
Priority to CA2873708A priority patent/CA2873708A1/fr
Priority to EP13722434.1A priority patent/EP2849805B1/fr
Publication of DE102012208376A1 publication Critical patent/DE102012208376A1/de
Priority to IN10399DEN2014 priority patent/IN2014DN10399A/en
Publication of DE102012208376B4 publication Critical patent/DE102012208376B4/de
Priority to AU2016222376A priority patent/AU2016222376B2/en
Publication of DE102012208376C5 publication Critical patent/DE102012208376C5/de
Application granted granted Critical
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE102012208376.6A 2012-05-18 2012-05-18 Satz und Verfahren zur Herstellung eines Radiopharmakons Active DE102012208376C5 (de)

Priority Applications (9)

Application Number Priority Date Filing Date Title
DE102012208376.6A DE102012208376C5 (de) 2012-05-18 2012-05-18 Satz und Verfahren zur Herstellung eines Radiopharmakons
CA2873708A CA2873708A1 (fr) 2012-05-18 2013-05-14 Kit et procede de production d'un compose radiopharmaceutique
EP13722434.1A EP2849805B1 (fr) 2012-05-18 2013-05-14 Kit et procédé de production d'un composé radiopharmaceutique
AU2013261855A AU2013261855B2 (en) 2012-05-18 2013-05-14 Set and method for the production of a radiopharmaceutical
US14/402,032 US20150098894A1 (en) 2012-05-18 2013-05-14 Set and method for the production of a radiopharmaceutical
BR112014028601A BR112014028601A2 (pt) 2012-05-18 2013-05-14 kit e método para a preparação de um radiofármaco
PCT/EP2013/059889 WO2013171185A1 (fr) 2012-05-18 2013-05-14 Kit et procédé de production d'un composé radiopharmaceutique
IN10399DEN2014 IN2014DN10399A (fr) 2012-05-18 2014-12-05
AU2016222376A AU2016222376B2 (en) 2012-05-18 2016-08-31 Set and method for the production of a radiopharmaceutical

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102012208376.6A DE102012208376C5 (de) 2012-05-18 2012-05-18 Satz und Verfahren zur Herstellung eines Radiopharmakons

Publications (3)

Publication Number Publication Date
DE102012208376A1 DE102012208376A1 (de) 2013-11-21
DE102012208376B4 DE102012208376B4 (de) 2015-07-23
DE102012208376C5 true DE102012208376C5 (de) 2018-02-01

Family

ID=48430785

Family Applications (1)

Application Number Title Priority Date Filing Date
DE102012208376.6A Active DE102012208376C5 (de) 2012-05-18 2012-05-18 Satz und Verfahren zur Herstellung eines Radiopharmakons

Country Status (8)

Country Link
US (1) US20150098894A1 (fr)
EP (1) EP2849805B1 (fr)
AU (2) AU2013261855B2 (fr)
BR (1) BR112014028601A2 (fr)
CA (1) CA2873708A1 (fr)
DE (1) DE102012208376C5 (fr)
IN (1) IN2014DN10399A (fr)
WO (1) WO2013171185A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170037727A (ko) 2015-09-25 2017-04-05 한국원자력연구원 뼈암 진단용 방사성 표지 키트 및 이의 제조방법

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004057225A1 (de) * 2004-11-26 2006-06-08 Johannes-Gutenberg-Universität Mainz Verfahren und Vorrichtung zur Isolierung eines chemisch und radiochemisch gereinigten 68Ga-Radionuklids und zum Markieren eines Markierungsvorläufers mit dem 68Ga-Radionuklid
WO2011106846A1 (fr) * 2010-03-03 2011-09-09 Australian Nuclear Science And Technology Organisation Purification de gallium-68

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009102378A2 (fr) * 2007-12-03 2009-08-20 Ge Healthcare Limited Purification d'un éluat de générateur 68ge/68ga du fe(iii), destinée à améliorer la radioactivité spécifique de radiopharmaceutiques à base de 68ga

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004057225A1 (de) * 2004-11-26 2006-06-08 Johannes-Gutenberg-Universität Mainz Verfahren und Vorrichtung zur Isolierung eines chemisch und radiochemisch gereinigten 68Ga-Radionuklids und zum Markieren eines Markierungsvorläufers mit dem 68Ga-Radionuklid
WO2011106846A1 (fr) * 2010-03-03 2011-09-09 Australian Nuclear Science And Technology Organisation Purification de gallium-68

Also Published As

Publication number Publication date
CA2873708A1 (fr) 2013-11-21
DE102012208376B4 (de) 2015-07-23
AU2013261855B2 (en) 2016-06-02
AU2013261855A1 (en) 2014-11-20
AU2016222376A1 (en) 2016-09-22
AU2013261855A2 (en) 2014-12-18
BR112014028601A2 (pt) 2017-07-25
AU2016222376B2 (en) 2017-10-05
DE102012208376A1 (de) 2013-11-21
WO2013171185A1 (fr) 2013-11-21
EP2849805A1 (fr) 2015-03-25
IN2014DN10399A (fr) 2015-08-14
EP2849805B1 (fr) 2018-05-09
US20150098894A1 (en) 2015-04-09

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Legal Events

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R012 Request for examination validly filed
R016 Response to examination communication
R016 Response to examination communication
R018 Grant decision by examination section/examining division
R026 Opposition filed against patent
R034 Decision of examining division/federal patent court maintaining patent in limited form now final
R206 Amended patent specification