DE102007012944A1 - Compound additive for food, cosmetics, pharmaceuticals or medical products is produced by fermentation of skimmed milk - Google Patents
Compound additive for food, cosmetics, pharmaceuticals or medical products is produced by fermentation of skimmed milk Download PDFInfo
- Publication number
- DE102007012944A1 DE102007012944A1 DE102007012944A DE102007012944A DE102007012944A1 DE 102007012944 A1 DE102007012944 A1 DE 102007012944A1 DE 102007012944 A DE102007012944 A DE 102007012944A DE 102007012944 A DE102007012944 A DE 102007012944A DE 102007012944 A1 DE102007012944 A1 DE 102007012944A1
- Authority
- DE
- Germany
- Prior art keywords
- protein
- milk
- produced
- acid
- protease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 235000020183 skimmed milk Nutrition 0.000 title claims abstract description 9
- 235000013305 food Nutrition 0.000 title claims abstract description 5
- 150000001875 compounds Chemical class 0.000 title claims abstract 4
- 239000002537 cosmetic Substances 0.000 title claims abstract 3
- 238000000855 fermentation Methods 0.000 title abstract description 3
- 230000004151 fermentation Effects 0.000 title abstract description 3
- 239000000654 additive Substances 0.000 title abstract 2
- 230000000996 additive effect Effects 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 229940127554 medical product Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 claims abstract description 13
- 235000018102 proteins Nutrition 0.000 claims abstract description 13
- 102000004169 proteins and genes Human genes 0.000 claims abstract description 13
- 108090000623 proteins and genes Proteins 0.000 claims abstract description 13
- 239000012466 permeate Substances 0.000 claims abstract description 12
- 108010046377 Whey Proteins Proteins 0.000 claims abstract description 11
- 239000005862 Whey Substances 0.000 claims abstract description 9
- 102000007544 Whey Proteins Human genes 0.000 claims abstract description 9
- 150000001413 amino acids Chemical class 0.000 claims abstract description 8
- 108091005804 Peptidases Proteins 0.000 claims abstract description 7
- 239000004365 Protease Substances 0.000 claims abstract description 7
- 239000000843 powder Substances 0.000 claims abstract description 7
- 239000002253 acid Substances 0.000 claims abstract description 6
- 235000013336 milk Nutrition 0.000 claims abstract description 4
- 239000008267 milk Substances 0.000 claims abstract description 4
- 210000004080 milk Anatomy 0.000 claims abstract description 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims abstract 12
- 235000014655 lactic acid Nutrition 0.000 claims abstract 6
- 239000004310 lactic acid Substances 0.000 claims abstract 6
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims abstract 5
- 102000015636 Oligopeptides Human genes 0.000 claims abstract 4
- 108010038807 Oligopeptides Proteins 0.000 claims abstract 4
- 241000894006 Bacteria Species 0.000 claims abstract 3
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Chemical compound OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 8
- 239000000047 product Substances 0.000 claims description 8
- 239000000126 substance Substances 0.000 claims description 3
- 102000035195 Peptidases Human genes 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims 4
- 102000014171 Milk Proteins Human genes 0.000 claims 2
- 108010011756 Milk Proteins Proteins 0.000 claims 2
- 239000002609 medium Substances 0.000 claims 2
- 244000005700 microbiome Species 0.000 claims 2
- 235000021239 milk protein Nutrition 0.000 claims 2
- 239000007858 starting material Substances 0.000 claims 2
- 241000588921 Enterobacteriaceae Species 0.000 claims 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 claims 1
- 244000046052 Phaseolus vulgaris Species 0.000 claims 1
- 235000010582 Pisum sativum Nutrition 0.000 claims 1
- 240000004713 Pisum sativum Species 0.000 claims 1
- 238000009825 accumulation Methods 0.000 claims 1
- 150000007513 acids Chemical class 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 238000004140 cleaning Methods 0.000 claims 1
- 235000014103 egg white Nutrition 0.000 claims 1
- 210000000969 egg white Anatomy 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 235000015097 nutrients Nutrition 0.000 claims 1
- 239000012460 protein solution Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 abstract description 3
- 239000004615 ingredient Substances 0.000 abstract description 2
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 description 2
- 239000008101 lactose Substances 0.000 description 2
- 235000021119 whey protein Nutrition 0.000 description 2
- BUHVIAUBTBOHAG-FOYDDCNASA-N (2r,3r,4s,5r)-2-[6-[[2-(3,5-dimethoxyphenyl)-2-(2-methylphenyl)ethyl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol Chemical compound COC1=CC(OC)=CC(C(CNC=2C=3N=CN(C=3N=CN=2)[C@H]2[C@@H]([C@H](O)[C@@H](CO)O2)O)C=2C(=CC=CC=2)C)=C1 BUHVIAUBTBOHAG-FOYDDCNASA-N 0.000 description 1
- -1 Amino acid compound Chemical class 0.000 description 1
- 230000001464 adherent effect Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/12—Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
- A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
- A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
- A23J3/341—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
- A23J3/343—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
- A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
- A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
- A23J3/346—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of vegetable proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
- A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
- A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
- A23J3/348—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of proteins obtained from waste materials
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/20—Milk; Whey; Colostrum
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Animal Husbandry (AREA)
- Physiology (AREA)
- Microbiology (AREA)
- Sustainable Development (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Claimed is a process for the production of a compound consisting of aminoacids and oligopeptides by the fermentation of protein in aqueous solution of skimmed milk, and/or milk permeates, or skimmed milk powder dissolved in water, permeate powder, and/or whey powder. In the process lactic acid bacteria and/or protease and/or acid, are added to the solution to lower the pH to 5 or less. This splits and breaks down any protein present. Further claimed is the use of this compound in liquid or dry form as an ingredient in liquid or dry form as an additive in food, cosmetics, pharmaceuticals or medical products.
Description
Stand der TechnikState of the art
Bekannt
sind die Patente
Nachteilig an diesen Verfahren ist der der Molke anhaftende Geruch, der sich auch auf die Folgeprodukte auswirken kann.adversely in this process is the whey adherent odor which is also affect the derived products.
Andererseits gibt es Magermilch und Permeat, beides Produkte, dem Bestandteile wie Fett und/oder Eiweiß entzogen wurde in verschiedenen Verfahren. Die Magermilch enthält neben Eiweiß noch den kompletten Milchzucker und viele bis alle wasserlöslichen Elemente (Vitamine, Mineralstoffe) der Milch. Das Permeat enthält meist nur noch die reinen Molkeproteine und Milchzucker, kein Kasein und kein Fett, hat den Vorzug, fast geruchlos zu sein.on the other hand There are skim milk and permeate, both ingredients how fat and / or protein was extracted in various procedures. The skimmed milk contains in addition to protein nor the complete Lactose and many to all water-soluble elements (Vitamins, minerals) of the milk. The permeate contains usually only the pure whey proteins and lactose, no casein and no fat, has the advantage of being almost odorless.
Es gibt auch UF-Permeat, ein durch Ultrafiltration total reduziertes Produkt, dem fast alle Fettanteile, Eiweißanteile, der Milchzucker und die Molkeproteine entzogen sind. Magermilch und Permeat werden in verschiedenen Formen in den Nahrungsmittelkreislauf gebracht. Als Getränk, als Pulver, als Beimischung etc.It also gives UF permeate, a totally reduced by ultrafiltration Product containing almost all fat, protein, protein Milk sugar and the whey proteins are withdrawn. Skimmed milk and Permeate come in various forms in the food cycle brought. As a drink, as a powder, as an admixture etc.
Das
hier angemeldete Verfahren veredelt Magermilch und Permeate aller
Art, auch UF-Permeate oder Nano-Permeate, auch mit Eiweißquellen
angereicherte Formen sowie aufgelöste Trockenformen von
Magermilch, Molke und Permeaten durch Fermentation und Umsetzung
mit bestimmten Bakterienstämmen. Ziel ist es wie in Patent
Dabei werden in Fermentern die genannten Stoffe vorgelegt, die Eiweißquellen und/oder Säurequellen und/oder Bakterienstämme und/oder Proteasen zugefügt und das ganze bei Temperaturkontrolle gären gelassen, wobei hin und wieder gerührt wird. Das so erzeugte Aminosäurencompound ist auf Grund seines pH-Wertes von meist unter 4 bis 3 sehr gut unter Luftabschluß haltbar.there In fermenters, the substances mentioned are presented, the sources of protein and / or acid sources and / or bacterial strains and / or proteases added and fermented at temperature control left, with occasional stirring. The so produced Amino acid compound is due to its pH of mostly under 4 to 3 very good under exclusion of air.
ZITATE ENTHALTEN IN DER BESCHREIBUNGQUOTES INCLUDE IN THE DESCRIPTION
Diese Liste der vom Anmelder aufgeführten Dokumente wurde automatisiert erzeugt und ist ausschließlich zur besseren Information des Lesers aufgenommen. Die Liste ist nicht Bestandteil der deutschen Patent- bzw. Gebrauchsmusteranmeldung. Das DPMA übernimmt keinerlei Haftung für etwaige Fehler oder Auslassungen.This list The documents listed by the applicant have been automated generated and is solely for better information recorded by the reader. The list is not part of the German Patent or utility model application. The DPMA takes over no liability for any errors or omissions.
Zitierte PatentliteraturCited patent literature
- - DE 2819940 [0001] - DE 2819940 [0001]
- - DE 3924559 [0001] - DE 3924559 [0001]
- - EP 0850044 [0001, 0005] - EP 0850044 [0001, 0005]
Claims (12)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007012944A DE102007012944A1 (en) | 2007-03-14 | 2007-03-14 | Compound additive for food, cosmetics, pharmaceuticals or medical products is produced by fermentation of skimmed milk |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007012944A DE102007012944A1 (en) | 2007-03-14 | 2007-03-14 | Compound additive for food, cosmetics, pharmaceuticals or medical products is produced by fermentation of skimmed milk |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE102007012944A1 true DE102007012944A1 (en) | 2008-09-18 |
Family
ID=39688267
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE102007012944A Withdrawn DE102007012944A1 (en) | 2007-03-14 | 2007-03-14 | Compound additive for food, cosmetics, pharmaceuticals or medical products is produced by fermentation of skimmed milk |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE102007012944A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102960536A (en) * | 2012-11-02 | 2013-03-13 | 南昌大学 | Dynamic high-pressure microfluidization-enzymolysis method for preparing hypoallergenic beta-lactoglobulin |
| CN104543330A (en) * | 2014-12-09 | 2015-04-29 | 浙江海洋学院 | Method for preparing high F ratio oligopeptide by fermenting ground sleeve-fish by using bacillus natto |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2819940B1 (en) | 1978-05-06 | 1979-06-13 | Henry Dipl-Ing Zimzik | Process for the production of detergent substances based on whey using lactic acid sticks |
| DE3924559A1 (en) | 1989-07-25 | 1991-05-16 | Nikolaus W Prof Dr Med Klehr | Use of whey in cleaning and care compsn. - for feminine hygiene, using careful control of pH |
| EP0850044A1 (en) | 1995-09-15 | 1998-07-01 | Advance AG | Process for obtaining amino acids from proteins and use of the amino-acid-containing products obtained |
-
2007
- 2007-03-14 DE DE102007012944A patent/DE102007012944A1/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2819940B1 (en) | 1978-05-06 | 1979-06-13 | Henry Dipl-Ing Zimzik | Process for the production of detergent substances based on whey using lactic acid sticks |
| DE3924559A1 (en) | 1989-07-25 | 1991-05-16 | Nikolaus W Prof Dr Med Klehr | Use of whey in cleaning and care compsn. - for feminine hygiene, using careful control of pH |
| EP0850044A1 (en) | 1995-09-15 | 1998-07-01 | Advance AG | Process for obtaining amino acids from proteins and use of the amino-acid-containing products obtained |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102960536A (en) * | 2012-11-02 | 2013-03-13 | 南昌大学 | Dynamic high-pressure microfluidization-enzymolysis method for preparing hypoallergenic beta-lactoglobulin |
| CN104543330A (en) * | 2014-12-09 | 2015-04-29 | 浙江海洋学院 | Method for preparing high F ratio oligopeptide by fermenting ground sleeve-fish by using bacillus natto |
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| Date | Code | Title | Description |
|---|---|---|---|
| 8139 | Disposal/non-payment of the annual fee |