DE102006044415A1 - Titanium implant for use as e.g. artificial hip joint socket, has surface staying in contact with organic material of organism for duration of implantation, where surface has small roughness - Google Patents

Titanium implant for use as e.g. artificial hip joint socket, has surface staying in contact with organic material of organism for duration of implantation, where surface has small roughness Download PDF

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Publication number
DE102006044415A1
DE102006044415A1 DE102006044415A DE102006044415A DE102006044415A1 DE 102006044415 A1 DE102006044415 A1 DE 102006044415A1 DE 102006044415 A DE102006044415 A DE 102006044415A DE 102006044415 A DE102006044415 A DE 102006044415A DE 102006044415 A1 DE102006044415 A1 DE 102006044415A1
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Prior art keywords
organic material
implantation
organism
duration
contact
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DE102006044415A
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German (de)
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DE102006044415B4 (en
Inventor
Bernhard Gottwald
Thomas Krock
Hans-Joachim Dr. Fischer
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Aap Implantate AG
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Aap Implantate AG
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A61L27/06—Titanium or titanium alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84—Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86—Pins or screws or threaded wires; nuts therefor
    • A61B17/866—Material or manufacture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
    • A61F2002/009—Special surfaces of prostheses, e.g. for improving ingrowth for hindering or preventing attachment of biological tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/30672—Features concerning an interaction with the environment or a particular use of the prosthesis temporary
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2002/30932—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth for retarding or preventing ingrowth of bone tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00011—Metals or alloys
    • A61F2310/00023—Titanium or titanium-based alloys, e.g. Ti-Ni alloys

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The implant has a surface staying in contact with an organic material of an organism for duration of implantation, where the surface has a small roughness. The surface roughness parameter is less than or equal to 0.05 micrometer or 0.7micrometer. The implant is made of titanium.

Description

Die Erfindung bezieht sich auf ein titanhaltiges Implantat, insbesondere zur temporären Implantation, mit einer Oberfläche, weiche für die Dauer der Implantation im Kontakt mit organischem Material eines Organismus steht.The The invention relates to a titanium-containing implant, in particular to the temporary Implantation, with a surface, soft for the duration of implantation in contact with organic material of a Organism stands.

Titanhaltige Implantate können beispielsweise aus Reintitan oder Titanlegierungen bestehen. Derartige Implantate finden Verwendung sowohl als Dauerimplantate, beispielsweise als künstliche Hüftgelenkpfannen, als auch als temporäre Implantate, beispielsweise als Osteosyntheseplatten. Titan als Werkstoff zeichnet sich durch seine gute Biokompatibilität aus. Für Dauerimplantate ist es vorteilhaft, wenn das Implantat und das umgebende organische Material, beispielsweise Bindegewebe oder Knochensubstanz, eine besonders feste Verbindung miteinander eingehen. Ohne diese feste Verbindung kann das Gewebe an Dauerimplantaten einer ständigen mechanischen Irritation ausgesetzt sein und sich in Folge dessen entzünden. Zur Erhöhung der Affinität zwischen dem eingesetzten Implantat und dem das Implantat umgebenen Organismus ist es üblich, die Oberfläche des Implantats zu behandeln. Aus dem Stand der Technik sind hierfür beispielsweise beschichtende oder die Oberfläche aufrauende Methoden bekannt. Zum Aufrauen der Oberfläche werden beispielsweise Sandstrahl- oder Säureätzverfahren eingesetzt. Als Beschichtungen sind beispielsweise Kollagenbeschichtungen bekannt.titanium-containing Implants can For example, consist of pure titanium or titanium alloys. such Implants find use both as permanent implants, for example as artificial Acetabular cups, as well as temporary Implants, for example as osteosynthesis plates. Titanium as a material is characterized by its good biocompatibility. For permanent implants, it is advantageous if the implant and the surrounding organic material, for example Connective tissue or bone substance, a particularly strong compound enter into each other. Without this solid connection, the tissue can permanent implants of a permanent be exposed to mechanical irritation and as a result ignite. To increase the affinity between the inserted implant and the implant Organism, it is common, the surface of the implant. For example, from the state of the art coating are coating or the surface roughening methods known. To roughen the surface For example, sandblasting or acid etching method used. When Coatings are known, for example, collagen coatings.

Methoden zur Erniedrigung der Affinität zwischen dem implantierten Implantat und dem das Implantat umgebenden Organismus sind aus dem Stand der Technik nicht bekannt.methods for lowering the affinity between the implanted implant and the implant surrounding it Organisms are not known from the prior art.

Der Erfindung liegt die Aufgabe zugrunde, ein titanhaltiges Implantat, insbesondere zur temporären Implantation, anzugeben, das ein Anwachsen von umgebendem organischem Material verhindert.Of the Invention is based on the object, a titanium-containing implant, especially for temporary Implantation to indicate that an increase of environmental organic Material prevented.

Die Aufgabe wird erfindungsgemäß bei einer Vorrichtung der eingangs genannten Art dadurch gelöst, dass die Oberfläche eine so geringe Rauigkeit aufweist, dass ein Anwachsen des umgebenden organischen Materials unterbunden wird.The Object is according to the invention in a device of the type mentioned solved in that the surface of a has such low roughness that an increase in the surrounding organic material is prevented.

Die Glattheit der Oberfläche allein reicht aus, um die Aufgabe zu lösen. Das erfindungsgemäße Implantat ist an seiner Oberfläche nicht chemisch verändert oder beschichtet, so dass Untersuchungen zur Verträglichkeit entfallen können. Die Glattheit der Oberfläche kann von dem Verwendungszweck des Implantats abhängig gemacht werden. So kann beispielsweise die vorgesehene Implantatierungsdauer und das vorgesehene umgebende organische Material berücksichtigt werden. Im Allgemeinen ist aber eine Rauigkeit vorgesehen, die Rauigkeitsparameter von Ra ≤ 0.05 μm und Rt ≤ 0.7 μm aufweist. Dabei entspricht der Ra-Wert dem arithmetischen Mittel der Abweichung von der Mittellinie des Profils. Dieser Wert wird auch als mittlere Rauigkeit bezeichnet. Der Rt-Wert ist ein Maß für die Rauigkeitstiefe. Diese Rauigkeitswerte sind signifikant kleiner als Rauigkeitswerte gängiger Titanimplantate. Der Stand der Technik weist Werte von Ra = 0,1–0,2 μm und Rt = 1,5–2 μm auf. Eine derartig geringe Rauigkeit des erfindungsgemäßen Implantats lässt sich beispielsweise durch Keramofinish oder elektrolytisch galvanische Methoden erreichen.The smoothness of the surface alone is enough to solve the task. The implant according to the invention is not chemically modified or coated on its surface, so that compatibility studies can be dispensed with. The smoothness of the surface may be dependent on the intended use of the implant. For example, the planned implantation duration and the intended surrounding organic material can be taken into account. In general, however, a roughness is provided which has roughness parameters of R a ≦ 0.05 μm and R t ≦ 0.7 μm. The R a value corresponds to the arithmetic mean of the deviation from the center line of the profile. This value is also called average roughness. The R t value is a measure of the roughness depth. These roughness values are significantly smaller than roughness values of common titanium implants. The prior art has values of R a = 0.1-0.2 μm and R t = 1.5-2 μm. Such a low roughness of the implant according to the invention can be achieved, for example, by ceramic finishing or electrolytic galvanic methods.

Im Folgenden wird die Erfindung anhand eines Ausführungsbeispiels schematisch in einer Zeichnung gezeigt.in the The invention will be described schematically with reference to an embodiment shown in a drawing.

Dabei zeigt diethere show the

1 ein Diagramm einer Profilanalyse der Oberfläche eines Titanimplantats gemäß dem Stand der Technik, und die 1 a diagram of a profile analysis of the surface of a titanium implant according to the prior art, and the

2 ein Diagramm einer Profilanalyse der Oberfläche eines erfindungsgemäßen Titanimplantats. 2 a diagram of a profile analysis of the surface of a titanium implant according to the invention.

Claims (2)

Titanhaltiges Implantat, insbesondere zur temporären Implantation, mit einer Oberfläche, welche für die Dauer der Implantation im Kontakt mit organischem Material eines Organismus steht, dadurch gekennzeichnet, dass die Oberfläche eine so geringe Rauigkeit aufweist, dass ein Anwachsen des umgebenden organischen Materials unterbunden wird.Titanium-containing implant, in particular for temporary implantation, having a surface which is in contact with organic material of an organism for the duration of the implantation, characterized in that the surface has such low roughness that growth of the surrounding organic material is prevented. Titanhaltiges Implantat nach Anspruch 1, dadurch gekennzeichnet, dass die Rauigkeit der Oberfläche einen Ra-Parameter von Ra≤ 0.05 μm und einen Rt-Parameter von Rt ≤ 0.7 μm aufweist.Titanium-containing implant according to claim 1, characterized in that the roughness of the surface has an R a -parameter of R a ≤ 0.05 μm and an R t -parameter of R t ≤ 0.7 μm.
DE102006044415A 2006-09-18 2006-09-18 Titanium-containing implant for temporary implantation Expired - Fee Related DE102006044415B4 (en)

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DE102006044415A DE102006044415B4 (en) 2006-09-18 2006-09-18 Titanium-containing implant for temporary implantation

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Application Number Priority Date Filing Date Title
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DE102006044415A1 true DE102006044415A1 (en) 2008-03-27
DE102006044415B4 DE102006044415B4 (en) 2013-03-21

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITPD20100070A1 (en) * 2010-03-09 2011-09-10 Sintea Plustek S R L PROSTHESIS WITH DIFFERENTIATED BIOLOGICAL RESPONSE
WO2012006334A1 (en) * 2010-07-09 2012-01-12 Synthes Usa, Llc Self-detaching layer for easy implant removal

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2044211T3 (en) * 1989-03-23 1994-01-01 Straumann Inst Ag METALLIC IMPLANT.
SE523288C2 (en) * 2002-07-19 2004-04-06 Astra Tech Ab An implant and a method of treating an implant surface
SE523236C2 (en) * 2002-07-19 2004-04-06 Astra Tech Ab An implant and a method of treating an implant surface
WO2005004941A1 (en) * 2003-07-08 2005-01-20 Poligrat Gmbh Cementable endoprostheses
DE202005002450U1 (en) * 2005-02-16 2005-07-07 Oraltronics Dental Implant Technology Gmbh Jaw implant suitable for insertion in bone is (partly) provided with homogeneous nanostructurized surface with specified surface topography and consists e.g. of titanium or alloy

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITPD20100070A1 (en) * 2010-03-09 2011-09-10 Sintea Plustek S R L PROSTHESIS WITH DIFFERENTIATED BIOLOGICAL RESPONSE
WO2011111083A3 (en) * 2010-03-09 2011-11-17 Sintea Plustek S.R.L. Prosthesis with differentiated biological response
WO2012006334A1 (en) * 2010-07-09 2012-01-12 Synthes Usa, Llc Self-detaching layer for easy implant removal
EP2982343A1 (en) * 2010-07-09 2016-02-10 Synthes GmbH Self-detaching layer for easy implant removal
US10166105B2 (en) 2010-07-09 2019-01-01 DePuy Synthes Products, Inc. Self-detaching layer for easy implant removal

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