DE10085149T1 - Verfahren zur Herstellung von Acarbose mit hohem Reinheitsgrad - Google Patents
Verfahren zur Herstellung von Acarbose mit hohem ReinheitsgradInfo
- Publication number
- DE10085149T1 DE10085149T1 DE10085149T DE10085149T DE10085149T1 DE 10085149 T1 DE10085149 T1 DE 10085149T1 DE 10085149 T DE10085149 T DE 10085149T DE 10085149 T DE10085149 T DE 10085149T DE 10085149 T1 DE10085149 T1 DE 10085149T1
- Authority
- DE
- Germany
- Prior art keywords
- acarbose
- purity
- production
- high degree
- degree
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1999/47093 | 1999-10-28 | ||
KR19990047093 | 1999-10-28 | ||
PCT/KR2000/001068 WO2001030796A1 (en) | 1999-10-28 | 2000-09-25 | A process for preparing acarbose with high purity |
Publications (2)
Publication Number | Publication Date |
---|---|
DE10085149T1 true DE10085149T1 (de) | 2002-12-05 |
DE10085149B4 DE10085149B4 (de) | 2008-06-19 |
Family
ID=19617338
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE10085149T Expired - Lifetime DE10085149B4 (de) | 1999-10-28 | 2000-09-25 | Verfahren zur Herstellung von Acarbose mit hohem Reinheitsgrad |
Country Status (6)
Country | Link |
---|---|
US (1) | US6649755B1 (de) |
JP (1) | JP3992497B2 (de) |
KR (1) | KR100383435B1 (de) |
AU (1) | AU7457300A (de) |
DE (1) | DE10085149B4 (de) |
WO (1) | WO2001030796A1 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100383435B1 (ko) * | 1999-10-28 | 2003-05-12 | 주식회사종근당 | 고순도 아카보스 제조방법 |
US20020111320A1 (en) * | 2000-08-07 | 2002-08-15 | Vilmos Keri | Method for purification of acarbose |
HRP20010792A2 (en) | 2001-10-26 | 2003-04-30 | Pliva D D | Acarbose purification process |
TWI280281B (en) * | 2003-12-02 | 2007-05-01 | Cpc Corp Taiwan | A novel process to recover and purify acarbose from fermentation broth |
US20100160624A1 (en) * | 2008-12-20 | 2010-06-24 | Ragus Holdings, Inc. | Process for Producing High-Purity Sucrose |
CN102030786A (zh) * | 2010-11-12 | 2011-04-27 | 丽珠集团新北江制药股份有限公司 | 一种阿卡波糖的制备方法 |
KR101675634B1 (ko) * | 2014-09-17 | 2016-11-11 | 한국항공우주연구원 | 원격 측정 장치 및 방법 |
CN106397506B (zh) * | 2016-08-31 | 2019-06-11 | 杭州中美华东制药有限公司 | 一种高品质阿卡波糖的纯化方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2064092C2 (de) | 1970-12-28 | 1983-06-01 | Bayer Ag, 5090 Leverkusen | Inhibitoren für Glykosidhydrolasen aus Actinomyceten |
DE2209832C3 (de) | 1972-03-01 | 1979-03-29 | Bayer Ag, 5090 Leverkusen | Herstellung von Saccharaseinhibitoren |
DE2209834C3 (de) | 1972-03-01 | 1978-04-20 | Bayer Ag, 5090 Leverkusen | Herstellung von Saccharase-Inhibitoren |
US4062950A (en) * | 1973-09-22 | 1977-12-13 | Bayer Aktiengesellschaft | Amino sugar derivatives |
DE2719912C3 (de) * | 1977-05-04 | 1979-12-06 | Bayer Ag, 5090 Leverkusen | Verfahren zur Isolierung von 0- |4,6-Dideoxy-4- [JJl S-O,4,6/5)-4,5,6-trihydroxy-3-hydroxymethyl-2cyclohexen-1-yl] -amino] - a -D-glucopyranosyl} -(I Pfeil nach rechts 4)-0- a D-glucopyranosyl-(l Pfeil nach rechts 4)-D-glucopyranose aus Kulturbrühen |
DE3439008A1 (de) * | 1984-10-25 | 1986-04-30 | Bayer Ag, 5090 Leverkusen | Polymerisate zur reinigung von acarbose |
DE3543999A1 (de) * | 1985-12-13 | 1987-06-19 | Bayer Ag | Hochreine acarbose |
KR940008059B1 (ko) * | 1992-08-28 | 1994-09-01 | 기아특수강 주식회사 | 노르말라이징에 의한 강인, 고청정 비조질 중형봉강의 제조방법 |
IT1293819B1 (it) * | 1997-08-05 | 1999-03-10 | Univ Massachusetts Lowell | Procedimento per la preparazione di acarbosio |
KR100383435B1 (ko) * | 1999-10-28 | 2003-05-12 | 주식회사종근당 | 고순도 아카보스 제조방법 |
-
2000
- 2000-09-25 KR KR10-2000-0056237A patent/KR100383435B1/ko active IP Right Grant
- 2000-09-25 JP JP2001533147A patent/JP3992497B2/ja not_active Expired - Fee Related
- 2000-09-25 DE DE10085149T patent/DE10085149B4/de not_active Expired - Lifetime
- 2000-09-25 WO PCT/KR2000/001068 patent/WO2001030796A1/en active Application Filing
- 2000-09-25 AU AU74573/00A patent/AU7457300A/en not_active Abandoned
- 2000-09-25 US US10/111,636 patent/US6649755B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO2001030796A1 (en) | 2001-05-03 |
KR20010050635A (ko) | 2001-06-15 |
JP3992497B2 (ja) | 2007-10-17 |
KR100383435B1 (ko) | 2003-05-12 |
DE10085149B4 (de) | 2008-06-19 |
AU7457300A (en) | 2001-05-08 |
JP2003512069A (ja) | 2003-04-02 |
US6649755B1 (en) | 2003-11-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8110 | Request for examination paragraph 44 | ||
8364 | No opposition during term of opposition | ||
R082 | Change of representative |
Representative=s name: GLEISS GROSSE SCHRELL UND PARTNER MBB PATENTAN, DE |
|
R081 | Change of applicant/patentee |
Owner name: CHONG KUN DANG PHARMACEUTICAL CORP., KR Free format text: FORMER OWNER: CHONG KUN DANG PHARMACEUTICAL CORP., SEOUL/SOUL, KR Effective date: 20141020 |
|
R082 | Change of representative |
Representative=s name: GLEISS GROSSE SCHRELL UND PARTNER MBB PATENTAN, DE Effective date: 20141020 |
|
R071 | Expiry of right |