DD271012A3

DD271012A3 - RODENTICIDE PASTE FOR THE PRODUCTION OF COAGERS FOR RESTORATION

Info

Publication number: DD271012A3
Application number: DD30563087A
Authority: DD
Inventors: Joachim Lorenz; Guenther Barysch
Original assignee: Delicia Veb
Priority date: 1987-08-03
Filing date: 1987-08-03
Publication date: 1989-08-23

Abstract

Rodentizide Paste auf Basis Zinkphosphid, Natriumkarboximethylzellulose, Monoethylenglykol und Wasser zur Herstellung von Giftkoedern fuer die Bekaempfung von Schadnagern. Die erfindungsgemaesse rodentizide Paste wird als akutwirdendes Frassgift auf von Nagern im jeweiligen Biotop bevorzugte Futtermittel gestrichen oder mit der Koedernahrung zu einem Teig vermengt und in Gaenge, Laufwege oder Futterplaetze der Nagetiere ausgelegt. Die erfindungsgemaesse Formulierung aus Zinkphosphid, Natriumkarboximethylzellulose, Monoethylenglykol und Wasser verhindert im wesentlichen eine Freisetzung von Phosphorwasserstoff, der auf die Nagetiere aeusserst repellent wirkt. Durch die Unterdrueckung der Repellentwirkung sowie den suessen Geschmack des Glykols ist eine gute Annahme und daraus resultierend eine ausreichende biologische Wirksamkeit des Mittels durch alle Nagetiere gegeben. Die erfindungsgemaesse Paste zeichnet sich durch hohe Lagerstabilitaet bei geeigneter Verpackung aus. Die Verwendung von Zinkphosphid als Wirkstoff schliesst Sekundaervergiftungen aus.Rodenticidal paste based on zinc phosphide, sodium carboxymethylcellulose, monoethylene glycol and water for the production of poisonous cohorts for the control of rodents. The rodenticidal paste according to the invention is excised as an acute infective poison on feeds preferred by rodents in the respective biotope or mixed with the koeder food into a dough and laid out in courses, running ways or feed places of the rodents. The novel formulation of zinc phosphide, sodium carboxymethyl cellulose, monoethylene glycol and water substantially prevents the release of phosphine, which has an extremely repellent effect on the rodents. By suppressing the repellent effect and the sweet taste of the glycol, a good assumption and, as a result, a sufficient biological effectiveness of the agent by all rodents is given. The inventive paste is characterized by high storage stability with suitable packaging. The use of zinc phosphide as active ingredient excludes secondary poisoning.

Description

Field of application of the invention The invention relates to an improved poison paste for the production of poison baits for the control of rodents,

insbesondere von Ratten und Wühlmäusen.especially of rats and voles.

The rodenticidal paste according to the invention is used as acute-acting feeding poison on rodent-preferred feed or Foodstuffs or mixed with the bait food to a porridge or dough and in courses and on the way or Feeding places of rodents designed. The rodenticidal paste according to the invention is characterized by high attractiveness to rodents and reaches after Application high mortality rates of all mouse and rat species. Characteristic of the known state of the art The most common form of rodent control is the use of bait preparations. A special form of formulation

sind die Giftpasten, dio sich insbesondere für die Zubereitung von Ködern aus dem im jeweiligen Biotop vorkommenden attraktivsten Futtermitteln anbieten. Das Prinzip vieler Köder besteht darin daß Samen, Früchte, Gemüse, Fleisch, Fisch u.a.are the poisonous pastes, which are particularly suitable for the preparation of baits from the most attractive feeds occurring in the respective biotope. The principle of many baits is that seeds, fruits, vegetables, meat, fish, etc.

Food and feed are mixed with a suitable active ingredient. In recent years came as bait

hergestellte Präparate auf den Markt, von denen vor allem die giftüberzogenen Getreidekörner bzw. Getreideprodukte, die inPrepared preparations on the market, of which especially the poison-coated cereal grains or cereal products, in

Plastic films sealed or provided with a polymer carrier bait as well as those baits, the plastic ^ took off Contain active ingredient, are mentioned. These preparations provided a whole series of practical advantages over the previous pesticides. you

sind jedoch mit dem Mangel behaftet, daß entweder bereits bei der Herstellung der Köder die anfängliche Attraktanz derHowever, they are subject to the defect that either in the preparation of the bait, the initial attraction of the

Lebensmittelbeatandteile is significantly restricted or their storage is relatively limited, d. H. Active substance content and attractiveness of the baits are reduced depending on the storage time. Gift pastes for the production of baits are characterized by the fact that only zu.n time of application of the Active substance is added to the most attractive bait base available in the biotope for the rodent rodent. Loss of attractiveness and drug degradation by storage are therefore excluded and the feeding habits of the animals

werden berücksichtigt.will be considered.

The active components of the bait formulation are all toxic substances that kill rodents

geeignet und allgemein bekannt sind, in Frage.suitable and generally known, in question.

Anticoagulants as long-term toxins with subacute toxicity have not been proven in the control of some rodent species. The animals instinctively detect avoiding soigo venomous baits, especially when receiving the bait in sublethal doses Discomfort arises. The use of these preparations can also be used in rodents to develop resistance

gegenüber den blutgerinnungshemmenden Substanzen führen.lead to the anticoagulant substances.

The use of zinc phosphide as edible poison in bait formulations for rodent control has long been known. This active ingredient has as an acute toxin very good rodenticidal properties, which in particular in the extremely difficult to

bekämpfenden Großen Wühlmaus zum Tragen kommen. Ködermittel auf Basis Zinkphosphid besitzen jedoch einen entscheidenden Nachteil. Die Annahme der Köder durch die Nagetiere ist z.T. stark reduziert bzw. wird total gemieden. DieFighting Big Vole come to fruition. However, baits based on zinc phosphide have a significant disadvantage. The acceptance of the baits by the rodents is z.T. greatly reduced or totally avoided. The

The cause lies in the instability or in the hydrolysis behavior of the active ingredient compared with the formulation components and Moisture influences justified. The released in these reactions phosphine already acts in low Concentrations on the rodents repellent. It is known, once by additions of certain chemicals to the formulation constituents and hydrophobing of the Wifkstoffteilchen (BRD OS DE 3337666 A1, International Cl.A 01 N 59/26) and on the other by surface sealing of the bait

mit einem wasserabweisenden bzw. wasserfesten Stoff (BRD OS 2158880, Int. Cl. A 01 N17/14) der Reaktivität von Zinkphosphid zu begegnen.with a water-repellent or water-resistant substance (BRD OS 2158880, Int.Cl. A 01 N17 / 14) to counteract the reactivity of zinc phosphide.

It is also known that with hardened gelatin it is attempted to protect the active substance from access by water

erwirken (DE 1143671 (451-17/08)).obtained (DE 1143671 (451-17 / 08)).

Both with finished baits z. B. based on grain and GetreideprozessungsprocHikten as well as in bait pastes, the Fungistatikum for preserving the preparation, but is also with liquid-tight envelope or

plastbeschichteten Zinkphosphid und Zumischen bestimmterchemischer Substanzen, die bevorzugt mit den Reaktionspartnern der Aktivsubstanz, wie Getreideinhaltsstoffen, Attraktantien, Fungistatika oder deren hydrolisierten Reaktionsprodukten, inplastified zinc phosphide and admixing certain chemical substances, preferably with the reaction partners of the active substance, such as cereal ingredients, attractants, Fungistatika or their hydrolyzed reaction products, in

To connect, released Phosphorwaaserstoff. The polymers coated with preparations are additionally associated with the disadvantage that the attractiveness of the bait

entscheidend verschlechtert wird, selbst wenn die Schutzschicht Lock- und Attraktivsto'fp f.nthält.is decisively worsened, even if the protective layer attracts and attracts attention.

In general, aqueous formulations containing zinc phosphide as the active ingredient are extremely difficult to handle

problematisch. Zinkphosphid besitzt amphoteren Charaktar. Sowohl bereits im schwach saueren als auch schwach alkalischenproblematic. Zinc phosphide has amphoteric character. Both in the slightly acidic and weakly alkaline

Miliei decomposes the active substance to form hydrogen phosphide. The use of appropriate and from the literature

bekannter Puffersubstanzen zur gezielten Regulierung bzw. Einstellung des pH-Wertes versagen bei Zinkphosphid ebenso wie eine Umhüllung der einzelnen Zinkphosphid-Partikelchen mit entsprechenden organischen Polymeren zum Schutz derknown buffer substances for targeted regulation or adjustment of the pH fail with zinc phosphide as well as a coating of the individual zinc phosphide particles with corresponding organic polymers for protecting the

Active substance before a reaction with water (diffusion of water through the polymer layer!). The more complete is a surface seal by hydrophobing the active ingredient, the stronger becomes the

biologische Wirksamkeit des rodentiziden Mittel J herabgesetzt. Der Wirkstoff passiert den Verdauungstrakt der Tiere, ohne mit der Magensäure reagieren zu können.biological efficacy of the rodenticidal agent J reduced. The active ingredient passes through the digestive tract of the animals without being able to react with the stomach acid.

The solution cited in DE 880817 (4513/06), due to the hydrolysis behavior of zinc phosphide, includes a hydrous Formulation. The paste base used are high molecular weight hydrocarbons. This will be an extremely high Hydrophobization of the active substance achieved, which inevitably significantly reduces the rodenticidal efficacy of MiUaIs

wird. Zusätzlich verlieren Köder, die mit solch einer rezeptierten Paste hergestellt werden, infolge des starken Eigengeruches dieser Kohlenwasserstoffe erheblich an Attraktivität für die Schadnager.becomes. In addition, baits made with such a formulated paste, due to the strong inherent odor of these hydrocarbons, significantly lose their appeal to rodents.

It is known a hydrous paste based on zinc phosphide, the VEO Deiicia, Delitzsch under 'Jet name Delicia- Rattekal paste was briefly on the market and containing as Fungistatikum 4-Hydroxibenzoesäuremethylestss. Decomposition of the Active ingredient in storage caused the cessation of production of this preparation. The storage instability of the product

führte bei undichter Verpackung zu einer spürbaren Verschlechterung der Konsistenz bis hin zum Austrocknen der Paste bzw. bei dichter Verpackung zum Platzen der Tuben.In the case of leaky packaging, the consistency was noticeably worsened, and the paste dried out or, in the case of tight packaging, the tube bursting.

In addition, when using the Delicia Rattekal paste, especially in the Kurzschwunzmauseatten a reduction of Attractiveness to observe (see below mortality rates, Item 6, Embodiment 1), indicating repellent effect

durch freigesetzten Phosphorwasserstcff zurückzuführen ist.is due to liberated Phosphorwasserstcff.

Object of the invention Object of the invention s ^; and hydrous rodenticides based on zinc phosphide, in particular for the control of Rats and voles are safe regardless of season and local conditions and are effective by the practitioner

leicht und gefahrlos gehandhabt werden können.can be handled easily and safely.

The use of zinc phosphide in the paste according to the invention is intended to secondary poisoning and harmful interference in Prevent biotope as the active substance both in the organism of the poisoned animals as in the soil to non-toxic Breaks down connections. The technical-economic progress of the invention should be expressed in the storage stability of the paste in gas-tight Find metal tubes with storage periods of at least 3 years. Explanation of the essence of the invention The invention is based on the object, rodenticidal agents with sufficient biological activity and high attractiveness

zu entwickeln, die auch bei reichlichem natürlichen Nahrungsmittelangebot von den Nagetieren bevorzugt aufgenommen werden.which are also favored by rodents, even with abundant natural food supply.

According to the invention the object is achieved by a mixture of carboxymethyl cellulose, monoethylene glycol, zinc phosphide and Water, which is characterized in that it contains 12 to 20% by weight of monoethylene glycol, 4 to 8% by weight of zinc phosphide, 4

bis 10Ma.-%an NatriumkarboximethyL'elluloseunddenRestzu 100Ma.-% an Leitungswasser enthält.to 10% by mass of sodium carboxymethyl cellulose and the remainder to 100% by mass of tap water.

It has surprisingly been found that monoethylene glycol is based on zinc phosphide-containing pastes

quellbarer Zelluloseverbindungen die angeführten Nachteile der bekannten technischen Lösungen weitestgehend ausschließt.swellable cellulose compounds largely excludes the mentioned disadvantages of the known technical solutions.

The presence of monoethylene glycol as a formulation component causes a significant reduction in release

von Phosphorwasserstoff, so daß Lagerzeiten der rodentiziden Paste konfektioniert in dicht schließenden Metalltuben mitof hydrogen phosphide, so that storage times of rodentiziden paste confectioned in tight-fitting metal tubes with

Storage periods of at least 3 years without affecting the utility properties of the product or packaging

ermöglicht werden. Infolge Unterdrückung der Repellentwirkurig von Phosphorwasserstoff ist eine äußerst gute Annahme der mit dieser Paste präparierten Köder durch alle Schadnagerarten gegeben. Außerdem verhindert Monoethylenglykol durch seine hygroskopischen Eigenschaften ein völliges Austrocknen des Mittels, d.h., die pastösa Konsistenz bleibt auch nach Applikation längere Zeit erhalten. Der süße Geschmack dieses Polyols verändert zusätzlich positiv die Attraktivität der Ködermitte! gegenüber den Schadnagern. Darüber hinaus konserviert der mehrwertige Alkohol die applika'.ionsgerechte Mischimg, so daß Zusätze an weiteren Konservierungsmitteln und Fungistatika entfallen können.be enabled. As a result of the suppression of the Repellentwirkurig of hydrogen phosphide is given a very good acceptance of the bait prepared with this paste by all Schadnagerarten. In addition, monoethylene glycol, by its hygroscopic properties, prevents complete drying out of the agent, i.e., the pasty consistency remains intact even after application. The sweet taste of this polyol additionally positively changes the attractiveness of the bait center! opposite the rodents. In addition, the polyhydric alcohol preserves the applika'.ionsgerechte Mischimg so that additives to other preservatives and fungistatics can be omitted.

It therefore represents a significant advantage with a high economic effect to provide t> <n poison, its odor and Taste has been thought to affect the rodents receiving a lethal dose of the active ingredient. On

weiterer Vorteil ist, daß das Einsetzen der Reaktion auf das Gift so lange verzögert wird, bis das Nagetier eine tödliche Menge verzehrt und den Bereich, in dem das Mittel ausgelegt ist, verlassen hat.Another advantage is that the onset of the reaction to the poison is delayed until the rodent has consumed a lethal amount and has left the area in which the agent is designed.

The death of the animals occurs within a few hours until 24 hours at the latest. after ingestion of the poison by development of Phosphoric acid under the influence of gastric acid. As the active ingredient in the body of the poisoned rodent is decomposed,

sind diese als Beutetiere für Greifvögel und mäusefressende Säugetiere ungefährlich.these are non-hazardous as prey for birds of prey and mouse-eating mammals.

The bait base used for the paste according to the invention may be any edible product, wio . B. Fruit, vegetables, cereals, meat or fish, preferably one chooses that for the rodent rod in the respective biotope

vorkommende attraktivste Futtermittel.occurring most attractive feeds.

Monoethylene glycol is known and accumulates in the hydrolysis' on ethylene oxide. However, there are other seductions too Production known to the person skilled in the art. Zinc phosphide is generally made by direct association of the elements at about 700 degrees Celsius. A well-known process for the preparation of cellulose compounds is the conversion of soda cellulose with Etherifying agents. Exemplary embodiments The following are examples that illustrate the invention. Example 1:

8 Gewichtsanteile Natriumkarboximethylzbllulose werden mit 7 Gewichtsanteilen Zinkphosphid vermischt und anschließend unter Rühren mit 15 Gewichtsanteilen Monoethylenglykol unJ ⁷O Gewichtsanteilen Leitungswasser versetzt. Nach einer8 parts by weight Natriumkarboximethylzbllulose be mixed with 7 parts by weight of zinc phosphide and then added with stirring with 15 parts by weight of monoethylene glycol and ⁷ parts by weight of tap water. After a

Life of about 12 hours and repeated stirring, the ready-to-use paste thus obtained is an edible Carrier applied or mixed with this or made up for storage in tubes. K prepared with this paste according to the invention (cut surfaces of halved apples coated with about 5 g of preparation)

unter Testbedingungen die Wirksamkeit an verschiedenen Nagetierarten gegenüber einer Paste geprüft, die in gleicher Weise hergestellt, anstelle des Glykols 1 Gewichtsantei! 4-Hydroxibenzoesäuremethylester als Fungistatikum enthielt (Delicia-Rattekal-Paste).Under test conditions, the efficacy tested on various rodent species over a paste prepared in the same way, instead of the glycol 1 Gewichtsantei! 4-Hydroxibenzoesäuremethylester as Fungistatikum contained (Delicia Rat Kal paste).

The following table shows a comparison of the activities of both pastes as a ratio of dead animals Expiry of 24 hours to the number of animals used in the experiment. In addition to the poisoned baits, the animals got las

übliche Futterangebot und zusätzlich zur Deckung ihres Flüssigkeitsbedarfes unbegiftete halbierte Äpfe.usual feed supply and in addition to cover their liquid need ungifted halved apes.

Tierart *Animal species * Durchschnittlicheaverage erfindungs-Inventions Mortalitätmortality Körpermasse proBody mass per gem. Pastegem. paste Paste mitPaste with Tieringtiering Fungistatikumfungistat Albino-RatteAlbino rat 20/2020/20 (Stamm Wistar)(Tribe Wistar) 320320 17/2017/20 Wanderrattebrown rat 9/109.10 Rattusnorvegicus)Rattusnorvegicus) 120120 4/104.10 Hausmaus-AlbinoHouse Mouse Albino 20/2020/20 (Musmusculusj(Musmusculusj 2525 10/1010/10 19/2019/20 Hausmaus—wildfarbenHouse mouse agouti 2222 8/108.10 Feldmausfield mouse 10/1010/10 (Microtusarvalis)(Microtusarvalis) 3232 2/102.10 Wühlmausvole (Arvicola(Arvicola 4/44.4 terrestris)terrestris) 110110 0/40/4

Example 2: According to another embodiment of the invention, in the same procedure as in Example 1, 7 parts by weight Zinc phosphide, 6 parts by weight of sodium carboxymethylcellulose, 18 parts by weight of monoethylene glycol and

69 Gewichtsanteile Leitungswasser formuliert. Die rodentizide Aktivität der so hergestellten Paste entspricht denFormulated 69 parts by weight of tap water. The rodenticidal activity of the paste thus prepared corresponds to the

Mortality rates as given in Example 1. The rodenti ide paste can be used to bait especially shrimp and field mice

z. B. mit frischen Möhren, Sellerie, Futterrüben u. a. in der Weise erfolgen, daß das Präparat in die ausgehölte Frucht gefülltz. B. with fresh carrots, celery, fodder u. a. done in such a way that the preparation filled in the oily fruit

For the bait of all species of long-tailed mosses has a poison slurry from a mixture of the paste according to the invention with Oatmeal, semolina, wheat, rye or other minced foodstuffs in a proportion of 1 part paste and 6 parts Bait matrix proven.

Claims

1. Rodenticidal paste based on zinc phosphide, source substance and water for the production of baits for rodent control, characterized in that to prevent hydrolysis, the formulation of 4 to 8 wt .-% zinc phosphide, 4 to 10Ma .-% Natriumkarboximethylzellulose, 12 to 20 Ma % Of monoethylene glycol and the balance to 100% by mass of tap water.

2. A process for the production of baits for the control of rodents, characterized in that the paste according to claim 1 applied to or in a preferred FuiL'-rmittel or mixed with the preferred bait food to a porridge or dough.