DD209733A1 - SKIN WASH PASTE - Google Patents

Abstract

The invention relates to a skin-washing paste, in particular for cleaning heavily soiled, discolored areas of skin with a protective effect against the penetration of phenolic substances caused by toxic Noxen in the skin. According to the invention, it contains 1-15% by weight of a comminuted, porous adsorber polymer comminuted in a mill having an inner surface area above 100 cubic meters / g and a particle size below 50 micrometers, furthermore 50-89% by weight of liquid glycol, 10-30% by weight .-% solid polyethylene glycol, up to 1 wt .-% fragrances and optionally washing-active substances and emulsifiers. The adsorber polymers used are those based on divinylbenzene, styrene, alkylstyrene or mixtures thereof.

Description

VEB CHEMICAL COMPANY BITTERFELD Bitterfeld, U. 9. 1982

2126.

Skin washing paste e Field of application of the invention

The invention relates to a skin-washing paste, in particular for the cleaning of heavily soiled, discolored areas of skin, with a protective effect against the penetration of phenolic substances caused by toxic loxes in the skin.

Characteristics of the known technical solutions

Are known washing pastes based on sand with certain particle sizes, which are cleaned by friction soiled skin. Furthermore, detergents containing surfactants such as surfactants, emulsifiers and other detergent-active substances are used. These include, for example, toilet soap containing alkali salts of higher fatty acids. Further, as anionic detergents are alkyl sulfates, alkyl sulfonates and arylalkyl sulfonates which are produced synthetically. Cationic active ingredients in detergents can be, for example, more or less complicated amino compounds. Finally, as a washing-active

- 2 - 2126

Substances non-ionic surfactants are mentioned, the z. B. derived from ethylene oxide.

In the application of these body cleansing agents, however, there are certain disadvantages. When using washing pastes based on abrasives and abrasives, there is a strong mechanical stress on the skin, which can sometimes lead to epithelial defects to pronounced dermatosis. With the use of detergents and soaps dirt particles can be removed well, but discolored areas of the skin are difficult or impossible to clean.

The cleaning of discolored areas of skin can also be done by means of organic solvents, but these often have harmful properties. The result is a toxic load on the body, since the natural acid mantle of the skin is destroyed by these organic solvents and resorptions of the solvents used by the skin can not be excluded ·

Object of the invention

The aim of the invention is to develop a skin washing paste which is particularly suitable for the cleaning of heavily soiled, discolored areas of the skin and at the same time protects against the penetration of toxic substances caused by phenolic substances into the skin.

Explanation of the essence of the invention

This object is achieved according to the invention in that the skin-washing paste contains 1-15% by weight of a porous adsorber polymer which has been comminuted in a mill and has an inner surface

2 over 100 m / g and a particle size below 50 / um, further 50 89 wt. 56 liquid glycol, 10 to 30 wt .-% of solid polyethylene glycol, up to 1 wt - . % Fragrances and optionally wash-active substances and emulsifiers.

- 3 - 2126

Adsorber polymers used are those based on divinylbenzene, styrene, alkylstyrene or mixtures thereof, optionally with up to 20% by weight of acrylic and / or methacrylic acid derivatives, but preferably of polymer-technical grade vinylbenzene.

Optionally, the polymers may also contain sulfonic acids, carboxylic acid, amino or ammonium groups.

The liquid glycols used are propylene glycol and / or polyethylene glycol having an average molecular weight of 600 and, as solid polyethylene glycol, having an average molecular weight of 5,000.

The skin-washing paste according to the invention is well-suited for easily removing, for example, aniline, fancy and onacol dyes, furthermore printing ink and carbon black and dyes from the cosmetic sector (make-up) from the skin, without this being damaged in any way.

Particularly advantageous is the fact that the skin washing paste at the same time against the Sindringen caused by phenolic substances toxic Noxen in the skin - such as in the chemical laboratory - protects.

The adsorber polymers are prepared in a known manner by suspension polymerization, wherein an addition of a precipitant and / or swelling agent to the polymerizable phase takes place.

In the preparation of the skin wash paste from the adsorbent polymer, it has been found that with respect to the required adsorptivity of the polymer, activation with glycols is superior to aqueous dispersions of such formulations.

- 4 - 2126

embodiment

The exemplary embodiments are intended to illustrate both the production of the skin-washing paste according to the invention and its cleaning or protective action *

example 1

Preparation of Adsorber Polymer:

The adsorber is prepared by polymerization of technical divinylbenzene (52 wt .-% divinylbenzene, 34 wt .-% ethylstyrene) in the presence of 35 wt .-% Parex gasoline, based on the total oil phase in a known manner in suspension polymerization · After evaporation of the gasoline and drying of the polymer, the grinding takes place in a pin mill. Subsequently, the adsorber is classified by means of an air classifier.

Characteristics of the adsorber:

2 Inner surface: 350 m / g Adsorber (determined with a

Hydrometer to Ströhlein) Grain size: 95 % 50 / Um

Preparation of the washing paste:

280 g of adsorber are ground with 306 g of polyethylene glycol 600 in an enamel bowl with a pestle. Thereafter, the portionwise addition of a further 1 700 g of polyethylene glycol 600 erfog. After homogenization of the mixture by stirring with an electric hand mixer, 500 g of polyethylene glycol 5,000, which were previously melted by heating to 50 ⁰ C in a separate vessel, added with constant stirring. The mixture is then stirred until it cools. Subsequently, 14 g of lavender oil were added to the paste with stirring.

- 5 - 2126

Example 2

Preparation of Adsorber Polymer

The adsorbent is prepared by polymerization of technical divinyl Henzen (52 wt .-% divinylbenzene, 34 wt .-% ethyl styrene) and addition of 5 wt "" = $ acrylonitrile in the presence of 55 wt »- Toluolj% based on the total oil phase, in Suspension polymerized After dampening of the toluene and drying the adsorber is stirred for 15 hours at 50 ⁰ C with an excess of 96 # iger sulfuric acid. The excess of sulfuric acid is filtered off and the adsorbent with dist. Washed out water. This is followed by treatment with sodium chloride. The adsorber is dried, comminuted in a pin mill and then classified using an air classifier.

Characteristics of the adsorber:

Inner surface: 420 m / g adsorber

Total capacity for acidic groups: 0.9 m vol / g

Grain size: 93 % 50 / Um

Preparation of washing paste: _v

280 g adsorber are analogously as described in Example 1, first rubbed in 300 g of polyethylene glycol 600 and then mixed with another 1 900 g. The amount of the subsequently added polyethylene glycol 5,000 is 306 g. Further preparation of the paste is carried out in the same way as described in Example 1.

- 6 - 2126

Example 3:

Preparation of the washing paste;

14Og adsorber - prepared analogously to Example 1 - are first mixed with 140 g Präwozell WOI 100 (alkoxylated alkylphenol) and then ground with 300 g of polyethylene glycol 600. Subsequently, 280 g of propylene glycol and 1 126 g of polyethylene glycol 5,000 are added in portions. The further workup is then carried out analogously to Example 1.

Example 4?

Cleaning of discolored areas of the skin

Kind of color cleaning effect the washing pastes according to substances or example Impairment 1 2 3 aniline-based very well Well Well Fantagenbasis very well Well Well carbon black-based very well Well Well Dyes off the cosmetics very well Well Well

(Lipsticks, eyebrow pencils, make-up)

Ormig dyes are good, good, good

In this case, the dyes were well removed after exposure periods of 1-2 minutes.

- 7 - 2126

Example 5:

Cleaning of soiled skin cleaning effect the Washing pastes according to Type of Ver example pollution 1 2 3 Well Well Well Fat and goo Well Well Well Hedolite preparation (dinitro-o-cresol) Well Well very well printing ink

After a period of 2-3 minutes, the skin was thoroughly cleansed.

Example 6;

Toxicological testing of skin washing pastes according to the invention

Test washing paste according to example

2 3

LDc ₀ po rat 5,000 mg / kg 5,000 mg / kg

LD ₅₀ dermal rat 7,000 mg / kg 7,000 mg / kg

Skin irritant - no irritation no irritation rabbit

Eye irritation test - no irritation no irritation rabbit

Skin irritation human no irritation no irritation (patch test)

- 8 - 2126

Example 7:

Prevention of penetration of noxa through the skin into the skin

x) Body of the test animal

Noxa protective effect of the washing pastes without washing example pastever-1 2 3 use

p »nitrophenol no laughing 10-20 % no proof 90 %

looking

1,3-dinitro- no laugh- no no proof 95 % proof

x) Noxa was detected by whole body analysis in % experimental animals: rat and rabbit

The skin of the animals was depilated and treated with the washing paste and then applied 10 mg / animal, After 1 hour exposure time was carried out after washing the treated skin killing the animals and a whole body analysis.

Claims (1)

- 9 - 2126 Brfindun ^ sans-prucli Skin-washing paste, in particular for cleaning heavily soiled, discolored areas of skin, having a protective effect against the penetration of toxic substances into the skin caused by phenolic substances, characterized in that they contain 1 to 15% by weight of a cross-linked, porous adsorber polymer comminuted in a mill Surface over 100 m / g and a particle size below 50 / um, further 50 - 89 wt. 5 & liquid glycol, 10 - 30 wt.-Sß solid polyethylene glycol, up to 1 wt .- ^ fragrances and optionally wash-active substances and emulsifiers , Skin washing paste according to item 1, characterized in that the adsorbent polymers used are those based on divinylbenzene, styrene, allcylstyrene or mixtures thereof, optionally with up to 20% by weight of acrylic and / or methacrylic acid derivatives, but preferably polymers of technical grade divinylbenzene which may optionally also contain sulfonic acid, carboxylic acid, amino or ammonium groups. Skin washing paste according to item 1 and 2, characterized in that as liquid glycols propylene glycol and / or Polyethylehglykol having an average molecular weight of 600 and as a solid polyethylene glycol such having an average molecular weight of 5,000 is used.