DD202523A5 - METHOD FOR PRODUCING TUBE FLUIDS AND AMPOULE - Google Patents

Abstract

The invention is intended to ensure the requirements of the processing industry and produce tube bottles and ampoules in such a clean condition that they can be filled with pharmaceutical products without purification. According to the invention, this is achieved by sealing off the severed lengths of tube at both ends by melting with the simultaneous application of an axial force, and forming the tubes or ampoules at these tube lengths sealed on both sides.

Description

Berlin, 17.12.1982 AP A 61 B / 242 673-2 61 112/23

Method for producing tube vials and jigs Application of the invention

The invention relates to a method for producing glass tube bottles and ampoules, in which a continuous glass tube is produced, tube lengths of any size are separated from this continuous glass tube and tubular tubes or ampoules are produced from these tube lengths by means of melting techniques.

Characteristic of the known technical solutions

Ampoules and pouches are mainly made from glass tubes. The glass tubes are continuously produced by placing the glass melt on a slightly inclined tube puller on a rotating mandrel and blowing in compressed air through the pierced shaft carrying the mandrel into the interior of the glass tube being formed. The tube is drawn and slid on a runway to a surgical device promoted, where pipe lengths of about 1.50 m separated and rolled aside. From such tube lengths the ampoules and tube bottles are made «

The Pläschchenfertigung takes place mainly on Karussellmasehinen in vertical tube position, in an intermittent or continuous mode or, more rarely, on horizontal machines ·

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In the carousel machines, the mouth of the first vial is first formed at the lower end of the glass tubes, then in a height corresponding to the length of the vial, the tube is strongly constricted and melted through, at the same time soils arise at the now separated first little pouch and the remaining tube a sting burner, the bottom is opened at the residual tube, after which the above-described steps are performed again on this remaining glass tube.

The ampoule production is also predominantly on carousels with vertical tube position, wherein also the formation of the first ampoule is made at the lower end · In contrast to the vial ¹ but the amp is all manufactured with its opening to the top, d. h · _her bottom is formed at the lower end of the glass tube · First, however, the tube is appropriate in one of the length of the vial. Height softens and stripped, creating the spit of the ampoule. On this skewer shoulder and onion are formed, and at the spit end, the pipe is durchsehmolzen, wherein the bottom pipe forms a floor · on this remaining glass tube, the described steps are repeated.

The known methods, both the tube manufacturing as well as the vial and vial manufacturing ways serious disadvantages. When separating the pipe lengths, fine pieces of glass are produced, some of which can get stuck at the end of the pipe.

When storing and transporting the tube lengths to the ampoule manufacturers, the tubes can pollute even more, which

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even more disadvantageous is the fact that the Reinheitsfdrderungen for the pharmaceutical industry have been tightened constantly ·

In vial and vial manufacture, it is often unavoidable, especially when opening a bottom by means of a jet flame, that combustion gases, oil vapors and more volatile glass components are blown into and precipitate inside the glass block or glaze ear. The ampoules must therefore be cleaned before pulling

Although it has already been proposed (DE-OS 1 901 413) »to avoid the formation of glass splinters in the separation of pipe lengths in that the continuous glass tube softens at a certain point and there is squished flat, but this proposal has been found to be impractical; In any case, he has never found his way into the technology of glass tube production.

Object of the invention

The aim of the present invention is to remedy the disadvantages described in both the glass tube production and in the box and vial ready-to-use and to meet the requirements of the processing industry.

Essence of the invention

The invention has for its object to provide a process for the manufacture of glass tube bottles and ampoules, in which a continuous glass tube produced by this kontinu-

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Sized glass tube lengths of any size and made of these tube lengths by means of melting techniques tube vials or ampoules, which supplies pipe surfaces and ampoules in such a clean state that they can be filled without cleaning with pharmaceutical products

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According to the invention, this object is achieved in that the separated tube lengths are sealed at both ends by melting with the simultaneous application of a force acting in the axial direction, and that the formation of the tube vials or ampoules is made on both sides closed tube lengths.

In the case of the double-sided closing of the tube lengths, at least one closed tube end with a convex outward shape is advantageously produced.

It is useful if at the two-sided closing ( j the tube lengths generated at least a plane closed pipe end, is.

At least one closed tube end with an inwardly curved shape is preferably produced when the tube lengths are closed on both sides.

In a further embodiment, the molding of the vial or the ampoule is carried out on the tube sides sealed on both sides according to known melt-shaping techniques, wherein a closed end which forms one of the two already existing ends or one during the said shaping.

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It may be a new, closed end, softened, and an overpressure created in the ear, so that this softened tube end bursts open.

A particular advantage is the fact that this overpressure is generated by the fact that at a remote location of this softened point, a heating of the pipe wall is performed from the outside, such that in the tube of the required pressure arises.

Conveniently, this heating of the pipe wall takes place during the formation of a batch, bottom or mouth or skewer, of the tube bottle or the ampoule at the same time.

According to a further feature of the invention, the method is characterized in that for the purpose of producing tube bottles

a) the tube sealed on both sides is softened in a vertical arrangement at its lower end,

b) at a remote location from this softened point, the tube length is heated from the outside, so that this softened soil bursts, whereupon

c) at this last batch the mouth of the tube is formed »

d) in a height corresponding to the length of the tube vial, the tube length is thermally severed, at the same time at this first tube and the vial

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remaining pipe length soils are formed, of which the soil resulting from the residual pipe length immediately bursts open again due to the internal overpressure that builds up the oak, and

e) the process steps a) to d) are repeated at this remaining, side sealed tube length.

Preferably, a tube length is used which has a closed tube end with an outwardly curved shape at the bottom.

It is particularly advantageous if the method is designed so that for the purpose of producing ampoules

m) the tube length sealed on both sides is softened in a vertical arrangement at its upper end, ₍

n) in the lower region of this tube length at a distance from the lower tube end, which corresponds approximately to the length of the ampoule to be formed, Spießformbrenner against the pipe court be tet, wherein the softened, upper end of the tube bursts, _t

o) in the area softened by these skewered formers, the shape of the ampule, namely skewer, shoulder and optionally onion, is formed,

p) over the spouting end of this first ampoule, the tube length is thermally severed, wherein at the same time a bottom is formed on the remaining tube length, and

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q) the process steps n) to ρ) are repeated at the now shortened pipe length.

Advantageously, a tube length is used which has a closed tube end with convex shape at the top »

Conveniently, a closed spit end is formed during thermal cutting.

The invention is thus based on the combination of two measures:

1) the two-sided closing of the pipe lengths still on the pipe drawing plant, whereby the pipe length in question in original purity to zunOFläschchen-, or ampoule na ut oma th can be transported, and

2) the manufacture of the vial or ampoule in such a way that no impurities can enter the molded glass container or the glass tube at all stages of manufacture.

This is achieved in that the tube closed on both sides is opened in the course of the forming process by softening one of the two trays and causing it to burst due to the generation of an internal overpressure.

Although it is a known measure to effect the opening of a softened bottom of a sealed tube piece by generating an overpressure in this earpiece (see, for example, DE-PS 934 432), this is done on glass bodies,

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which were already separated to the length of one ampoule or two ampoules, and in particular to glass tubes that were open on both sides from the beginning.

embodiment

The invention is explained in more detail below by way of exemplary embodiments:

I. Production of tubes sealed on both sides

The tube lengths separated from the continuous glass tubing string (eg, by thermal shock) are softened at both ends (successively or simultaneously) by burners, and the softened ends are pulled out by means of an axial force until the tube is ... coincides and a closed pipe cross-section is obtained. The sintered glass, which may be hanging at the end of the pipe, sinters and is removed.

In contrast to the proposal according to DE-OS 1 901 413, in which by means of a radially acting force was trying to close the pipe end, it was found that only when pulled out in the longitudinal direction of the pipe length a tube sheet is obtained with the desired density and shape.

If desired, the purity of the tube lengths can be further improved by treating the tube length after separation from the tubing string in a section which is separated from the rest of the room by laminar flow to prevent accidental contamination of the tube.

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The shape of the tube bottom thus produced can be adapted to the intended use of the ear length; Preferably, one of the two closed tube ends is formed with an outwardly curved shape and the other end with a flat shape.

The shaping of the pipe end takes place in any suitable manner.

Ha production of pipe vials

The sealed tube on both sides is used vertically on a carousel machine, so that it can be held as needed by an upper and / or a lower chuck. The bottom of the tube is softened. On a remote location of the tube, a heat source is directed; Due to the overpressure inside the pipe, the softened soil bursts. Here, the mouth of the vial is shaped by conventional techniques *

In a distance of this mouth corresponding to the length of the jet, the pipe is thermally constricted and finally cut. · Two floors form; the bottom is the bottom of the first molded tube vial, which is finished in the usual way; the upper one bursts open again as a result of the overpressure building up in the pipe, whereby a more uniform opening is created than when using a jet flame according to the conventional method. This residual pipe is now treated exactly as described above for the uncut pipe length.

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61 112/23 II.b. Preparation of ampoules

The tube closed on both sides is placed vertically on an automatic turret · Its upper bottom is softened, and at the lower end, at a distance equal to the length of the ampoule, the burner is directed against the tube, so that the softened upper pressure is created by the resulting internal overpressure Soil bursting · The upper soil is preferably broken in such a way that it bursts laterally when the pipe is heated.

At the point against which the burners are directed, the ampoule shape, namely spit, shoulder and optionally the onion of the ampoule is then formed.

Above the spit end, the tube is now melted through; In this case, a closed spit end is formed on the ampoule and a bottom on the residual tube. The above-described process steps are repeated on this residual tube.

Although the residual pipe is no longer sealed on both sides in this procedure, there is no risk of contamination of the "inside of the pipe because there is constant overpressure and the opening produced above preferably lies on the side of the pipe." The decisive prerequisite for the purity of the resulting ampoules is that the tube passes in closed form on both sides of the carousel and is opened only after building up an overpressure.

In the production of ampoules having a spit at both ends, at the place where the

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Spit mold burners are directed, two skewers shaped.

The claimed method can also be applied to other vial and tube vial manufacturing processes than those exemplified in the examples, as long as the feature combination according to the invention is taken into account, namely use of a tube length closed on both sides in the virgin state, and formation of the vial or vial in such a vial Way that never contaminating vapors can get into the interior of the container or the residual tube.

Claims (12)

A method for producing glass tube vials and ampoules in which a continuous glass tube is produced, tube lengths of any size are separated from this continuous glass tube, and tube tubes or ampoules are produced from these tube lengths by means of melting techniques, characterized in that the severed tube lengths are melted at both ends be closed with simultaneous application of an axial force acting, and that the formation of the tube vials, or the ampoules is made of these sealed on both sides tube lengths. 2 6 7 8? ^ 17.12.1982 C «» L · \) I W £. AP A 61 B / 242 673-2 61 112/23 d) in a corresponding length of the Rohrfläschchena the pipe length is thermally severed, at the same time at this first Rohrflaschohen and the rest of the pipe length soils are formed, of which the resulting at the tail pipe length immediately bursts by the building up internal pressure again, and e) the process steps a) Uis d) are repeated at this remaining closed on both sides of the tube length 2 S 7 8 2 ^ 17.12.1982 AP A 61 3/242 673-2 61 112/23 the small pouch or ampoule is made, wherein a closed end, which may be one of the two existing ends or a new, closed band formed during said molding softens, and an overpressure is created in the pipe such that it softens Pipe end bursting · 2 Method according to item 1, characterized in that, when the tube lengths are closed on both sides, at least one closed tube end is produced with an outwardly curved shape. Method according to item 1, characterized in that at least one plane closed pipe end is produced when the pipe lengths are closed on both sides. 4 · Method according to item 1, characterized in that at the closed on both sides of the tube lengths at least one closed pipe end is produced with inwardly curved shape. 5 · Method according to one of the items 1 to 4, characterized in that at the closed tube lengths according to known melt-forming techniques shaping Method according to point 5 », characterized in that this overpressure is produced by the fact that. a location of this softened areas remote location, a heating of the pipe wall is made from the outside, such that in the tube of the required pressure arises, -6.JAN, 1983 * Ü6Ü224 7. "Process according to item 6, characterized in that this heating of the tube wall takes place simultaneously during the formation of a batch, bottom or mouth or spit, of the tube vial or of the ampoule. 8. The method according to any one of points 5 to 7, characterized in that for the purpose of producing Rohrfläsehchen a) the tube sealed on both sides is softened in a vertical arrangement at its lower edge, b) at a location remote from this softened end of the pipe length is mentioned from the outside, so that this softened soil bursts, whereupon e) the mouth of the ear vial is formed at this last batch, A method according to item 3, characterized in that a 'pipe length is used which has at the bottom a closed tube end with an outwardly curved shape. 10, method according to one of the items 5 to 7, characterized in that, for the purpose of producing ampoules m), the tube length sealed on both sides is softened in a vertical arrangement at its upper end, n) in the lower region of this tube length at a distance from the lower tube end, which corresponds approximately to the length of the ampoule to be formed, Spießformbrenner be directed against the tube, wherein the softened, upper end of the tube bursts, o) in the area softened by these skewered formers, the shape of the ampule, namely skewer, shoulder and optionally onion, is formed, p) above the spit end of this first ampoule the tube 2Λ2 87 / IS " 12/17/1982 AP A 61 3/242 678-2 61 112/23 length is thermally severed, at the same time a bottom is formed on the remaining length of tube, and q) the process steps n) to p) are repeated at the now shortened pipe length 11. The method according to item 10, characterized in that a tube length is used, the above has a closed tube end with outwardly curved shape. 12 · Method according to item 10 or 11, characterized in that during thermal cutting a closed spit end is formed.