DD129642A5 - Verfahren zur aufspaltung von dl-alanin,3-fluor-dl-alanin und 2-deutero-3-fluor-dl-alanin - Google Patents

Verfahren zur aufspaltung von dl-alanin,3-fluor-dl-alanin und 2-deutero-3-fluor-dl-alanin

Info

Publication number
DD129642A5
DD129642A5 DD7700197629A DD19762977A DD129642A5 DD 129642 A5 DD129642 A5 DD 129642A5 DD 7700197629 A DD7700197629 A DD 7700197629A DD 19762977 A DD19762977 A DD 19762977A DD 129642 A5 DD129642 A5 DD 129642A5
Authority
DD
German Democratic Republic
Prior art keywords
allanine
fluor
deutero
distributing
Prior art date
Application number
DD7700197629A
Other languages
German (de)
English (en)
Inventor
John M Chemerda
George Gal
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DD129642A5 publication Critical patent/DD129642A5/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30Preparation of optical isomers
    • C07C227/34Preparation of optical isomers by separation of optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/487Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Fire-Extinguishing Compositions (AREA)
DD7700197629A 1976-03-05 1977-03-02 Verfahren zur aufspaltung von dl-alanin,3-fluor-dl-alanin und 2-deutero-3-fluor-dl-alanin DD129642A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/664,328 US4048224A (en) 1976-03-05 1976-03-05 Process for resolving alanine, 3-fluoro and 2-deutero-3-fluoro-DL-alanine

Publications (1)

Publication Number Publication Date
DD129642A5 true DD129642A5 (de) 1978-02-01

Family

ID=24665546

Family Applications (1)

Application Number Title Priority Date Filing Date
DD7700197629A DD129642A5 (de) 1976-03-05 1977-03-02 Verfahren zur aufspaltung von dl-alanin,3-fluor-dl-alanin und 2-deutero-3-fluor-dl-alanin

Country Status (16)

Country Link
US (1) US4048224A (pt)
JP (1) JPS52106814A (pt)
AT (1) AT348501B (pt)
CS (1) CS195327B2 (pt)
DD (1) DD129642A5 (pt)
DK (1) DK67477A (pt)
ES (1) ES456379A1 (pt)
FI (1) FI770493A (pt)
HU (1) HU172989B (pt)
NL (1) NL7701643A (pt)
NO (1) NO770524L (pt)
PL (1) PL105883B1 (pt)
PT (1) PT66225B (pt)
SE (1) SE7701710L (pt)
SU (1) SU786887A3 (pt)
YU (1) YU49477A (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2749203C2 (de) * 1977-11-03 1981-12-17 Riedel-De Haen Ag, 3016 Seelze Verfahren zur Racematspaltung von DL-alpha-Aminocarbonsäuren und diastereomere Salze
FR2430413A1 (fr) * 1978-07-07 1980-02-01 Anvar Procede de preparation d'alpha-aminoacides optiquement actifs, et leurs derives
US4264590A (en) * 1979-05-23 1981-04-28 Abbott Laboratories Antibacterial peptide
US4582931A (en) * 1984-12-24 1986-04-15 Merck & Co., Inc. Preparation of 2-Deutero-D-serine
KR200234713Y1 (ko) 1998-12-31 2001-11-22 구자홍 전동압축기의프레임지지장치

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3028395A (en) * 1955-03-28 1962-04-03 Parke Davis & Co Process for the resolution of optically active acids
US3381031A (en) * 1962-04-18 1968-04-30 Univ Australian Resolution of racemic amino acids

Also Published As

Publication number Publication date
NL7701643A (nl) 1977-09-07
SE7701710L (sv) 1977-09-06
US4048224A (en) 1977-09-13
SU786887A3 (ru) 1980-12-07
FI770493A (pt) 1977-09-06
PL105883B1 (pl) 1979-11-30
PT66225B (en) 1979-01-17
DK67477A (da) 1977-09-06
AT348501B (de) 1979-02-26
CS195327B2 (en) 1980-01-31
PT66225A (en) 1977-03-01
YU49477A (en) 1982-06-30
HU172989B (hu) 1979-01-28
NO770524L (no) 1977-09-06
JPS52106814A (en) 1977-09-07
ES456379A1 (es) 1978-04-16
ATA138277A (de) 1978-07-15

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