DD129642A5 - Verfahren zur aufspaltung von dl-alanin,3-fluor-dl-alanin und 2-deutero-3-fluor-dl-alanin - Google Patents

Verfahren zur aufspaltung von dl-alanin,3-fluor-dl-alanin und 2-deutero-3-fluor-dl-alanin

Info

Publication number
DD129642A5
DD129642A5 DD7700197629A DD19762977A DD129642A5 DD 129642 A5 DD129642 A5 DD 129642A5 DD 7700197629 A DD7700197629 A DD 7700197629A DD 19762977 A DD19762977 A DD 19762977A DD 129642 A5 DD129642 A5 DD 129642A5
Authority
DD
German Democratic Republic
Prior art keywords
allanine
fluor
deutero
distributing
Prior art date
Application number
DD7700197629A
Other languages
German (de)
English (en)
Inventor
John M Chemerda
George Gal
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DD129642A5 publication Critical patent/DD129642A5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/34—Preparation of optical isomers by separation of optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fire-Extinguishing Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
DD7700197629A 1976-03-05 1977-03-02 Verfahren zur aufspaltung von dl-alanin,3-fluor-dl-alanin und 2-deutero-3-fluor-dl-alanin DD129642A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/664,328 US4048224A (en) 1976-03-05 1976-03-05 Process for resolving alanine, 3-fluoro and 2-deutero-3-fluoro-DL-alanine

Publications (1)

Publication Number Publication Date
DD129642A5 true DD129642A5 (de) 1978-02-01

Family

ID=24665546

Family Applications (1)

Application Number Title Priority Date Filing Date
DD7700197629A DD129642A5 (de) 1976-03-05 1977-03-02 Verfahren zur aufspaltung von dl-alanin,3-fluor-dl-alanin und 2-deutero-3-fluor-dl-alanin

Country Status (16)

Country Link
US (1) US4048224A (da)
JP (1) JPS52106814A (da)
AT (1) AT348501B (da)
CS (1) CS195327B2 (da)
DD (1) DD129642A5 (da)
DK (1) DK67477A (da)
ES (1) ES456379A1 (da)
FI (1) FI770493A (da)
HU (1) HU172989B (da)
NL (1) NL7701643A (da)
NO (1) NO770524L (da)
PL (1) PL105883B1 (da)
PT (1) PT66225B (da)
SE (1) SE7701710L (da)
SU (1) SU786887A3 (da)
YU (1) YU49477A (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2749203C2 (de) * 1977-11-03 1981-12-17 Riedel-De Haen Ag, 3016 Seelze Verfahren zur Racematspaltung von DL-alpha-Aminocarbonsäuren und diastereomere Salze
FR2430413A1 (fr) * 1978-07-07 1980-02-01 Anvar Procede de preparation d'alpha-aminoacides optiquement actifs, et leurs derives
US4264590A (en) * 1979-05-23 1981-04-28 Abbott Laboratories Antibacterial peptide
US4582931A (en) * 1984-12-24 1986-04-15 Merck & Co., Inc. Preparation of 2-Deutero-D-serine
KR200234713Y1 (ko) 1998-12-31 2001-11-22 구자홍 전동압축기의프레임지지장치

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3028395A (en) * 1955-03-28 1962-04-03 Parke Davis & Co Process for the resolution of optically active acids
US3381031A (en) * 1962-04-18 1968-04-30 Univ Australian Resolution of racemic amino acids

Also Published As

Publication number Publication date
FI770493A (da) 1977-09-06
YU49477A (en) 1982-06-30
PL105883B1 (pl) 1979-11-30
SU786887A3 (ru) 1980-12-07
JPS52106814A (en) 1977-09-07
HU172989B (hu) 1979-01-28
NO770524L (no) 1977-09-06
CS195327B2 (en) 1980-01-31
ES456379A1 (es) 1978-04-16
ATA138277A (de) 1978-07-15
SE7701710L (sv) 1977-09-06
US4048224A (en) 1977-09-13
DK67477A (da) 1977-09-06
AT348501B (de) 1979-02-26
PT66225A (en) 1977-03-01
PT66225B (en) 1979-01-17
NL7701643A (nl) 1977-09-07

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