CZ441499A3 - Body odors absorbing preparations containing cyclodextrin, perfume composition and powder carrier and method of their application - Google Patents

Abstract

The present invention relates to a perfumed powder formulation absorbing body odors and moisture and its use. This composition, intended for application to the skin, consists of 0.1 % to 25 wt. % uncomplexed cyclodextrin, 5 to 60 wt. % high moisture absorbent, 0.05-15 wt. % of the perfume composition with the encapsulated perfume or 0.01 to 5 wt. % free perfume composition perfume from a powdered carrier.

Description

Body Odor Absorbent Preparations, Containing Cyclodextrin, Perfume Composition, and Powdered Carrier, and Method of Use

Subject of the technique

The present invention relates to a composition for absorbing odor and moisture, and to a method for its use. In particular, the present invention relates to such a powdered perfumed composition which is suitable for use on the skin surface of the entire body and is capable of absorbing a wide range of body odors and sweat forming on the skin.

BACKGROUND OF THE INVENTION

Body odor is most commonly caused by fatty acids present on the skin and odors of microbial origin. There are many microorganisms on human skin, which are fed by various substances secreted by the skin (sweat and sebum), skin cell debris, skin decomposition products and degradation products of these organisms themselves, unpleasant body odors are mainly odors of organic substances with different structures and functional groups such as amines, acids, alcohols, aldehydes, ketones, phenol derivatives, polycyclic compounds, indoles, aromatic compounds, polyaromatic compounds, and the like. They may also be caused by compounds containing functional groups with sulfur atoms such as thiol, mercaptan, sulfide and / or disulfide groups.

Numerous attempts have been made to alleviate or absorb body odors. The possibility of ridding the microbes causing the body odor of the humid environment they need to multiply and grow has been explored. These attempts consisted, inter alia, in the use of powders and / or sweating suppressants. The powders and powder-based formulations described in the prior art have limited absorption properties. Sweating-reducing agents are not always suitable as body odor-reducing agents, as they may interfere with thermal regulation processes when applied to the entire body by suppressing perspiration by astringent salts. In addition, such salts may be irritating to a large number of users, particularly when used in sensitive areas such as the pelvic region.

Other deodorants for the suppression of odors derived from skin secretions, which are described in the chemical and cosmetic literature, are emulsion sticks or suspension sticks, aerosols, rolling applicators, tampons, hand-held sprayers and possibly soaps. These known deodorants reduce odors in various ways. For example, U.S. Patent No. 5,525,331 to Betts, issued June 11, 1996, describes compositions that inhibit the growth of microorganisms in body secretions. Deodorants may also contain antibacterial agents that help destroy or reduce the amount of bacteria present on the skin and thereby minimize the odor produced by bacterial decomposition of skin secretions.

Zeolites are known odor absorbers. These odor-absorbing solids, however, like the known activated carbon-based odor-absorbing substances, lose their functional properties when wetted. Therefore, these bodily odor absorbers are not suitable when moistened with body fluids or to act in aqueous solution because they lose their desirable ability to absorb odors. Zeolites may additionally give a harsh feel when applied to the skin in too large an amount.

In addition to the previously mentioned attempts to reduce or absorb body odors, numerous attempts have been made to mask body odors with other odors or perfumes. However, perfumes are often unable to fully hide body odors and may be irritating to the user if they are used alone to suppress odor.

SUMMARY OF THE INVENTION

Accordingly, there is a need for an improved perfumed odor and moisture absorbent composition and methods of use, wherein the composition is substantially free of irritating astringent astringents and is safe and effective for use throughout the body. In addition, it is particularly desirable that the composition applied to the skin is capable of absorbing a wide range of body odors and excess moisture which is not fully suppressed by the aforementioned compositions.

It has been found that such suppression of body odors and possibly absorption of liquids can be safely achieved throughout the body by using a skin-applied composition which contains non-complexed cyclodextrins as the odor absorbing substance, furthermore highly effective moisture absorbing components, perfume and a powdered carrier. Surprisingly, it has been found that perfume can be added without reducing the ability of uncomplexed cyclodextrins to absorb odors. A particular advantage of the present invention is the ability to provide comfortable and non-irritating protection against odor and possibly against liquids in areas where the skin is covered and which can be very sensitive, such as pelvis, outer sheath, lower abdomen and buttocks, breasts, and folds. skin. In addition, it has been found that these effects can be achieved by using the formulation on a powdered carrier, which may optionally have other properties such as the ability to protect and / or moisturize the skin.

Unless otherwise indicated, all percentages, ratios, and proportions referred to in the specification, examples and claims are by weight, weight ratios, and parts by weight.

BRIEF DESCRIPTION OF THE INVENTION

The present invention provides a odor and moisture absorbent powdered perfume composition containing 0.1 to 25% by weight uncomplexed cyclodextrin, may contain 5 to 60% by weight highly effective moisture absorbers, further comprising a perfume composition selected from the group consisting of 0.05 to 15% % by weight of the odor absorbing composition, from the encapsulated perfume and from 0.01% to 5% by weight of the composition; % of the odor absorbing composition of the free perfume and mixtures thereof and from a powdered carrier. The compositions of the present invention may also contain an odor control agent selected from the group consisting of zeolites, activated carbon, sodium bicarbonate, bacterostatics, and perspiration suppressants. The present invention also relates to methods of using the above compositions.

DETAILED DESCRIPTION OF THE INVENTION

The present invention relates to a perfumed powdered composition suitable for reducing the intensity of body odor and absorbing moisture from a covered area of the skin. The present invention also relates to an article of manufacture comprising the compositions of the present invention applied to a flexible delivery device. The composition of the present invention comprises solids, preferably having a particle size of from 1 µm to 100 µm, more preferably 1 to 60 µm, and most preferably 1 to 20 µm.

As used herein, particle size refers to the largest dimension of primary particles.

The term covered skin as used herein refers to areas of the human or mammalian body covered by underwear, such as the pelvic area, the lower abdomen and buttocks area, the breast and folds of the skin, or the area susceptible to inflammation, where skin contact. As used herein, excess moisture means an undesirable and / or unhealthy concentration of bodily fluids found on the skin. The phrase body fluid as used herein means sweat, sebum, liquid substances formed by the passage of water through the skin, vaginal excretion, urine, and mixtures thereof. The term body odor as used herein means odors produced by the natural activity of a human or mammalian body. Such odors are, inter alia, odors produced by microorganisms of the skin (i.e., bacterial decomposition of skin secretions), urine, or vaginal excretion, and mixtures thereof. The term skin as used herein means human or mammalian skin. The phrase whole body means all the outer surface of human or mammalian skin. The term vaginal odor refers specifically to those bodily odors that originate from the pelvic region of the pelvis, especially the vagina, lower abdomen and buttocks.

A detailed description of the basic and auxiliary components used in the processes of the present invention is provided below.

Cyclodextrin

The term cyclodextrin as used herein means known cyclodextrins, such as unsubstituted cyclodextrins containing six to twelve glucose units, particularly α-cyclodextrin, β-cyclodextrin, γ-cyclodextrin and / or

derivatives thereof and / or mixtures thereof. The term uncomplexed cyclodextrin as used herein means that the cavities of the cyclodextrin used in the composition of the present invention are substantially unfilled prior to application to the skin, such that the cyclodextrin can absorb various odor molecules upon application to the skin.

Preferred cyclodextrins for use in the methods of the invention are α-cyclodextrin, β-cyclodextrin, γcyclodextrin and / or derivatives thereof. More preferably, these preferred cyclodextrins are β-cyclodextrin, hydroxypropyl acyclodextrin, hydroxypropyl β-cyclodextrin, methyl derivative acyclodextrin, or methyl derivative β-cyclodextrin. Most preferably, the cyclodextrin is β-cyclodextrin.

Mixtures of cyclodextrins are also preferred. These compositions absorb body odors to a greater extent by forming complexes with a large variety of molecules of different molecular weights that are characterized by a strong odor. The cyclodextrin concentrations used are 0.1 to 25% by weight, preferably 1 to 20% by weight, more preferably 2 to 15% by weight, most preferably 3 to 10% by weight.

The formation of a complex between cyclodextrin and molecules with a strong odor is accelerated by the presence of body fluids. This is advantageous for the user since cyclodextrins found on dry skin do not enter other environmental odors into their cavities, making them less effective in absorbing body odors. After solubilization of cyclodextrins with body fluids, the cavities become accessible to form inclusion complexes with body odor molecules. Thus, the accessibility of solubilized uncomplexed cyclodextrin is essential for the efficacy of the formulation to reduce the intensity of body odors.

Small particle size cyclodextrins are characterized by improved surface accessibility for odor absorption and are therefore preferred. In this document, the particle size is the largest

primary particle size. By small particle cyclodextrins is meant cyclodextrins having a particle size of less than 12 µm, preferably less than 10 µm, and more preferably less than 5 µm. More complete information regarding cyclodextrins, cyclodextrin derivatives, and particle size of cyclodextrins suitable for use in the methods of the invention can be found in U.S. Patent No. 5,429,628, Trinh et al., Issued June 4, 1995, herein incorporated by reference as link.

Highly effective moisture absorbers

Highly effective moisture absorbents may be included in the compositions of the present invention to aid in the reduction of excess moisture on the covered skin and to increase the fluidity (non-caking susceptibility of moisture-induced sintering) of the compositions of the present invention. The term highly effective moisture absorbent as used herein refers to silicon dioxide, silicates or carbonates, wherein these silicates and carbonates are formed by the reaction of carbonate or silicates with alkali (IA group metals), alkaline earth metals (group IIA metals) or transition metals. Preferred highly effective moisture absorbents are calcium silicate, amorphous silica, calcium carbonate, magnesium carbonate, or zinc carbonate, and mixtures thereof, some specific examples of silicates and carbonates suitable for use in the methods of the present invention are more fully described in Van. Nostrand Reinhols Encyclopedia Chemistry, 4th Edition, pp. 155, 169, 556, and 849 (1984), which is incorporated herein by reference.

Preferred are synthetic grades of highly effective moisture absorbents, particularly as regards silica and silicates, due to the security risks associated with the use of crystalline silica. These synthetic types are obtained 99 99> ♦ ♦ 9

They are controlled by industrially conducted controlled chemical reactions, not by the extraction of these substances and their subsequent refining. Synthetic carbonates suitable for use in the methods of the invention may be obtained from various manufacturers such as Mallinckrodt or Whittaker, Clark and Daniels. Examples of synthetic calcium silicate suitable for use in the processes of this invention are Hubersorb® 250 or Hubersorb® 600, manufactured by I.M. Huber.

Highly effective moisture absorbers comprise 5 to 60 wt%; more preferably 10 to 50 wt.% and most preferably 20 to 40 wt.% of the total weight of the composition.

Perfume

Perfume is an essential component of the present invention and is present therein at a concentration that is non-irritating to the skin and / or respiratory tract of the general user, but which is recognizable by human smell either before and / or after application to the skin. Perfumed preparations must be safe for use on the skin. The perfumes of the present invention comprise perfume ingredients. These perfumes may be either in the form of free perfume or in the form of encapsulated perfume or in the form of mixtures thereof. The perfume typically constitutes 0.01 to 20% by weight of the total weight of the odor absorbing composition.

Encapsulated perfume

0.05 to 15% by weight, preferably 0.1% to 10% by weight, more preferably 0.2% to 8% by weight, and even more preferably 0.5% to 5% by weight of the odor absorbing composition are encapsulated perfumes . Encapsulation of the perfume helps prevent premature loss of perfume into the atmosphere, while avoiding excessive intensity of fragrance which could be unpleasant for the user.

• 00 0 00 00 in »·« ··· 0 · 0 ·

# 0000

000 0 0 0 0 0 0 · ·· · 000 ·

0000 000 0 * · 00 0 · ♦ ·

The term encapsulated perfume as used herein refers to perfumed compositions which are contained or preferably encapsulated in a carrier. Examples of encapsulation processes suitable for the preparation of the encapsulated perfume of the present invention are the formation of cyclodextrin / perfume inclusion complexes, coacervate encapsulation, cell matrix encapsulation, preparation of perfume-filled porous particles, and combinations thereof. The encapsulated perfume is preferably released by a moisture-based activation mechanism, which releases the perfume from its encapsulated form after moistening the encapsulated perfume, for example by sweat or other body fluids. Since the perfume is released only after moistening, the skin irritation caused by the perfume is minimized.

Cyclodextrin / perfume inclusion complexes are preferred not only because of their preferred activation of moisture release but also for their efficacy and ease of processing. The perfume content of the cyclodextrin complex is considerably low, for example 10% to 18% by weight in the β-cyclodextrin / perfume complex. Cyclodextrin / perfume inclusion complexes useful in the present invention, particle size, and methods for their preparation are described in detail in U.S. Patent No. 5,429,628 to Trinh et al., Issued June 4, 1995, which is incorporated herein by reference. . The smallest effective amount of the cyclodextrin / perfume inclusion complex must be added to the odor absorbing compositions of the present invention to achieve the desired perfume concentration release. The effective amount is usually an amount corresponding to a concentration range of 0.01 to 10% by weight, preferably 0.1% to 3% by weight, more preferably 0.2% to 2% by weight, based on the total weight of the odor absorbing composition.

Coacervate encapsulation of perfumes is a commonly known encapsulation method in which a drop of one or more perfume components is enclosed in a solid-forming material.

4 4 4 4

4 4 4 4

444 44 44 walls. When encapsulating perfume in a cell matrix, one solid particle contains many small drops with one or more perfume components that are tightly enclosed in the cells. The water-soluble (moisture activated) cell matrix perfume microcapsules suitable for use in the present invention and their preparation are described in detail in the US patent

No. 5,429,628, Trinh et al., issued Jun. 4, 1995, which is incorporated herein by reference. The water soluble cell matrix perfume microcapsules suitable for use in the methods of the invention preferably have a size of 0.5 to 60 µm, more preferably 1 to 50 µm, most preferably 2 to 40 µm.

Coacervate encapsulation of perfume and encapsulation of perfume in the cell matrix are preferred because the perfume content thereof may be 60-80%. Effective concentrations of perfume coacervate microcapsules and / or cellular matrix perfume microcapsules are generally in the range of 0.002 to 6 wt%, preferably 0.007 to 1 wt%, more preferably 0.01 to 0.5 wt%, based on the total weight of the composition odor absorbing.

The perfume-free porous particles are ingested if a slow continuous perfume release is desired. Perfume-containing porous particles are particles in which the perfume is embedded in the matrix without further packaging and the release is controlled by diffusion. Porous particles containing perfume composed of a starch matrix may be prepared according to the US patent

No. 5,267,531, Appel et al., issued Dec. 7, 1993, which is incorporated herein by reference. An example of suitable porous particles, which are starch granules, is disclosed in Whistler et al., Food Technology, June 1994, pp. 104-105, which is incorporated herein by reference. These porous perfume-filled particles can be coated with suitable materials to improve perfume retention. Preferred sizes of these porous particles are in the range of 10 to 60 µm, more preferably 15 to 40 µm.

• ft · · · • · ♦ · · · · · · · · · ft ft ft ft ft ft ft ft ft ft ft ft ft · ···· ··· ·· ··· · ♦ ··

Preferably, the encapsulated perfume, irrespective of its form, consists of perfumes selected predominantly from two groups, namely, a) of volatile perfumes having a boiling point under normal pressure of less than 260 ° C, more preferably less than 250 ° C, and groups (b) consisting of perfumes with a significantly low odor threshold and mixtures of perfumes of the two groups. The boiling points of many perfumes are listed, for example, in Perfume and Flavor Chemicals (Aroma Chemicals) by Steffen Arctander, published by the author in 1969 and incorporated herein by reference. Typically, at least 50% by weight, preferably at least 60% by weight, more preferably at least 70% by weight, and most preferably at least 80% by weight of the encapsulated perfume comprises perfumes of groups a) and b) above.

Examples of substances which are particularly suitable as volatile perfume components include, but are not limited to, allocimene, allyl caproate, allyl cyclohexane acetate, allyl cyclohexanepropionate, allyl heptanoate, amyl acetate, amylpropionate, anethole, anisic acid aldehyde, acetyl, benzyl aldehyde, benzaldehyde, benzaldehyde, benzaldehyde , benzyl formate, benzyl isovalerate, benzyl propionate, β-γ-hexenol, butyl benzoate, butyl caproate, 4-tert-butylcyclohexylformate, camphene, camphor resin, carvacrol,

1-carveol, d-carvone, 1-carvone, cinnamylformate, cis-jasmone, cis-3-hexenyl acetate, cis-3-hexenylbutyrate, cis-3-hexenylcaproate, cis-3-hexenyl tetiglate, cis-3-hexenylvalerate, citral ( neral), citronellol, citronellyl acetate, citronellylformate, citronellyl isobutyrate, citronellylnitrile, citronellyloxyacetaldehyde, citronellylpropionate, cumidinal alcohol, aluminic acid aldehyde, Cyclal C, cyclohexylethyl acetate, β-damascone,

2-decenal, decylaldehyde, dihydromyrcenol, dihydromyrcenylacetate, dimethylbenzylcarbinol, dimethylbenzylcarbinyl acetate, dimethylbenzylcarbinylpropionate, dimethylphenylethylcarbinyl acetate, 3,7-dimethyloctanal, dimethyloctanol, diphenyloxide, ethyl acetate, ethyl acetoacetate, dimethyl acetate

• 9 9 • 9 9 • 9 ♦ · 9 9 • 9 9 9 9 • • 9 9 9 9 9 9 • • • • • 9 9 9 • • • · · 99 99 9 9 9 99

ethylbutyrate, ethylhexyl ketone, ethylphenylacetate, eucalyptol, fenchylacetate, fenchylalcohol, floracetate (tricyclodecenylacetate), frutene (tricyclodecenylpropionate), γ-methylionone, γ-nonalactone, geraniol, geranyl acetate, geranylacetobate, geranylacetobate, heptylacetate, heptylisobutyrate, heptylpropionate, hexenol, hexenylacetate, hexenylisobutyrate, hexylacetate, hexylformate, hexylisobutyrate, hexylisovalerate, hexylneopentanoate, hexyltiglate, hydratropic alcohol, hydroxycitronellal, α-ionone, β-γ-isonate, , isobutyl benzoate, isobutyl caproate, isononyl acetate, isononyl alcohol, isomenthol, isomenthone, isononylacetate, isopulegol, isopulegylacetate, isoquinoline, lauric aldehyde (dodecanal), lavandulylacetate, ligustral, d-limonene acetate, lininallyl oxide, lininallyl oxide, lininallyl oxide, lininallyl oxide, , linalylpropionate, menthon, menthyl acetate, methylacetophenone, methylamyl ketone, methyl anthranilate, methyl benzoate, methyl benzyl acetate, methylchavicol, methylleugenol, methylheptenone, methylheptin carbonate, methyl heptyl ketone, methylhexyl ketone, α-iso-methyl jon, nonyl acetaldehyde, methyl octyl acetaldehyde, methyloctyl ketone, methylphenylcarbinyl acetate, methyl salicylate, myrcene, myrcenylacetate, neral, nerol, neryl acetate, nonalactone, nonylbutyrate, nonyl alcohol, nonyl acetate, nonylaldehyde, octanol, octyl acetate, octyl acetate, octylaldehyde, d-limonene, p-cresol, p-cresyl-methyl ether, p-cymene, p-isopropyl-p-methyl-acetophenone, phenethylanthranilate, phenoxyethanol, phenylacetaldehyde, phenylethyl acetate, phenethyl alcohol, phenethyldimethylcarbinol, α-pinene, β- pinene, α-terpinene, prenylacetate, propylbutyrate, pulegon, safrole, α-terpinene, γ-βerpinene,

4-terpinenol, terpineol, terpinolene, terpinyl acetate, terpinyl propionate, tetrahydrolinalool, tetrahydromyrcenol, thymol, δ-undecalactone, γ-undecalactone, undecanal, undecenal, undecyl alcohol, Veratrol, Verdox, Vertenex and vitidine.

φ φ φ φ φ · · φ φ

ΦΦ φ * * * * * * * * * φ

Examples of other suitable volatiles that can be used in the perfumes of this invention are amylbenzoate, β-caryophylene, cinnamyl alcohol, diphenylmethane, dodecalactone, ethylmethylphenylglycidate, eugenol, fenchylacetate, γ-n-methyl ionone, heliotropin, indole, isobutyl quinoline (isobutyl quinoline) ), methyl N-methyl anthranilate, p-methoxyacetophenone, phenethylbutytate, phenylheptanol, phenylhexanol, and phenoxyethylpropionate.

A preferred encapsulated perfume comprises at least 5, preferably at least 6, more preferably at least 7, and even more preferably at least 8 different volatile components. The most common perfume components, which are derived from natural materials, contain a large number of substances. Each such material, when used as part of the encapsulated perfume of the present invention, is counted as a single component for the purposes of defining the present invention.

The use of small amounts of perfume ingredients having low fragrance perception thresholds can improve the fragrance of the perfume, although these ingredients are not as volatile as the aforementioned perfume ingredients belonging to group (a). The phrase fragrance perception threshold is the lowest vapor concentration of this material that can be detected by smell. Fragrance Perception Threshold and Some Fragrance Perception Thresholds are discussed, for example, in Standardized Human Olfactory Thresholds by M. Devos et al., Published by IRL Press at Oxford University Press in 1990; and Compilation Odor and Taste Threshold Values Data, edited by F. A. Fazzalari, ASTM Data Series DS 48A, American Society for Testing and Materials, 1978, both of which are incorporated herein by reference. Perfume ingredients which do not belong to group (a) above but which have a considerably low odor threshold and are suitable for use in the methods of the invention are selected from the group consisting of: ambrox, bacdanol, benzylsalicylate, fruit bat, cetalox, cis-3-hexenylsalicylate, cymal, ebanol, ethylanthranilate, ethylmethylphenylglycidate, ethylvanillin, dihydro-iso-jasmonate, flflf 99 99 99

999 9 9 9 9 9 99 fl flfl flflfl · fl fl fl flfl · fl · ···· 9 flflfl flfl fl · «flflfl flflfl flfl flflfl flfl flfl γ-dodekalacton, floracetát, florhydral, frutén heliotropine, of -ionone, β-ηοηοη, isoeugenol, α-isomethylionone, lilial, lyral, methyldihydrojasmonate, methyl-p-naphthylketone, β-naphtholmethylether, p-hydroxyphenylbutanone, undekalactone, vanillin. and mixtures thereof. These materials are preferably present in low concentrations in addition to the volatile components of group a), and typically comprise less than 20% by weight, preferably less than 15% by weight, more preferably less than 10% by weight, of the perfume.

There are also volatile components of group (a) which have a considerably low odor perception threshold and are suitable for use in the methods of the invention. Examples of such components are allylamyl glycolate, anethole, benzylacetone, butylantranilate, cinnamyl alcohol, cyclal C, cyclogalbanate, 4-decenal, ethyl-2-methylbutyrate, eugenol, damascenone, α-damascone, fructone, herbavert, indole, iso-cycllocitral, methylone, linaloolate , methylheptin carbonate, methyl isobutenyltetrahydropyran, methyl-nonyl ketone, nerol, p-anisic acid aldehyde, phenylacetaldehyde, and undecylene acid aldehyde.

Free perfume

The perfume may also be in the form of free perfume. The term free perfume as used herein means perfume that is not encapsulated. If desired, the free perfume may be diluted in a solvent to aid in its incorporation into the compositions of the present invention. Suitable solvents include those used herein in cosmetic skin care compositions and those disclosed in Cosmetic Bench Reference, 1994, p. 54, which is incorporated herein by reference. The free perfume may contain conventional components in concentrations of 0.01 to 5% by weight, preferably 0.05% to 3% by weight, more preferably 0.05% to 2% by weight, and most preferably 0.1% to 1% by weight. % based on the total weight of the odor absorbing composition.

• Β

ΒΒΒΒ Β «« - - - - - - - -

Β ΒΒΒΒ Β Β Β Β Β Β

ΒΒΒΒ Β ΒΒΒ ΒΒΒΒ

· ΒΒΒ ΒΒ · ·· ΒΒ ΒΒ

Powder carrier

In order to be easily applied and spread over the skin, the cyclodextrins and the highly effective moisture absorbents suitable for use in the present invention need to be dispersed in a pharmaceutically acceptable powdered carrier. As used herein, the term pharmaceutically acceptable means a pulverulent substance that is suitable for topical use on the skin without being toxic, irritating, causing allergic reactions and the like. This powdered carrier also prevents the solubilized cyclodextrin from being washed out of the skin. Examples of powdery carriers suitable for use in the methods of the present invention are powdery substances whose use for such purposes is known and which are harmless to human skin. Such powders include, but are not limited to, corn starch, talc, rice starch, oat starch, tapioca starch, microcrystalline cellulose (e.g., Avicel ®), octenyl succinate starch derivative (manufactured by National Starch & Chemical Co. under the names Dry Flo ® Pure, Dry Flo ®). XT, and / or Dry Flo® PC), kaolin, and mixtures thereof. The use of corn starch is preferred.

The powdered carrier suitable for use in the methods of the invention comprises 10 to 95% by weight, preferably 15 to 80% by weight, more preferably 25 to 50% by weight, of the total weight of the composition.

Odor-reducing aid

The compositions of the present invention may contain zeolites, carbon odor reducing agents, sodium bicarbonate, bacterostatics, and / or perspiration reducing agents as an odor reducing agent.

4 4 4 44 44

444 4,444 4,444 444 444 444 444 44 4

4,444,444

4444 444 44 444 44 44

The term zeolite, as used herein, refers to non-fibrous zeolites. The zeolites may be present in the compositions of the present invention in concentrations of 0.1% to 25% by weight, preferably 1 to 15% by weight, based on the total weight of the composition. A detailed description of zeolites suitable for use in the methods of the present invention is set forth in U.S. Patent No. 5,429,628 to Trinh et al., Issued June 4, 1995, which is incorporated herein by reference.

The carbonaceous odor intensity reducing agents described in U.S. Patent No. 5,429,628 may be used in the present invention at concentrations ranging from 0.1% by weight to the total weight of the formulation.

Alkali metal carbonates and / or alkali metal bicarbonates such as sodium bicarbonate, potassium bicarbonate, potassium carbonate, cesium carbonate, sodium carbonate, and mixtures thereof may be added to the powder formulations of this invention to improve the ability of these formulations to reduce the acid odor. An example of the use of sodium bicarbonate as an armpit deodorant is given in U.S. Pat. No. 4,382,079, Marschner, issued May 3, 1983, which is incorporated herein by reference. Preferred salts are sodium carbonate monohydrate, potassium carbonate, sodium bicarbonate, potassium bicarbonate, and mixtures thereof. The alkali metal carbonates and bicarbonates are usually present in concentrations of 0.1 to 30% by weight, preferably 0.2 to 20% by weight, more preferably 0.3 to 10% by weight, based on the total weight of the powdered composition.

The antimicrobial agents used in the methods of the invention are selected from the group consisting of bacteriostats, fungicides and mixtures thereof. Antimicrobial agents destroy and / or suppress bacteria and / or fungi present on the skin. Preferred antimicrobial agents are zinc phenolsulfonate, zinc oxide, triclosan, Zelec® AM manufactured by DuPont, zinc ricinoleate, zinc undecylenate, and their diameters. · Φ φ φ φ směsi směsi směsi směsi směsi směsi směsi směsi směsi směsi směsi směsi směsi směsi směsi More preferred are zinc phenolsulfonate, zinc oxide and triclosan. Triklosan is manufactured by Ciba-Geigy as Irgasan DP-300. Examples of antimicrobial agents suitable for use in the methods of this invention are set forth in Cosmetic Bench Reference, 1994 edition, p. 10, which is incorporated herein by reference. The antimicrobial compositions are used in the compositions of the present invention in concentrations of 0.01 to 25% by weight, preferably 0.1% to 10% by weight, based on the total weight of the composition of the invention.

When used in the armpit, one of its components may be a sweating agent. Examples of known sweating suppressants are provided in the Cosmetic Bench Reference, 1994 edition, p. 13, which is incorporated herein by reference. When used in the compositions of the present invention, the concentration of the perspiration reducing agent is in the range of 0.1 to 25% by weight, based on the total weight of the composition.

Skin protectants and moisturizers

The compositions of the invention may also contain skin protecting and moisturizing agents. As used herein, the term skin protectant and moisturizer refers to skin protectants, emollients and moisturizers.

Skin protection agents suitable for use in the methods of the present invention are disclosed in the Cosmetic Bench Reference, 1994 edition, p. 53; and Monograph on Skin Protectant Drug Products for Over-the-Counter Human Use, 21 CFR 347. Preferred skin protecting agents are corn starch, kaolin, mineral oil, sodium bicarbonate, polydimethylsiloxanes, zinc oxide, ground oatmeal and mixtures thereof. If skin-protecting agents are used, their concentration is in the range of 0.1 to 80% by weight, preferably at least about 9% by weight to about 9% by weight.

9 ··· 999 9 · 999

9 9 9

9 9 9

9 9 9

9 9 9

99% to 0.1% to 30% by weight, most preferably 0.1% to 10% by weight, based on the total weight of the formulation.

Softening and skin moisturizing agents suitable for use in the methods of this invention are disclosed in the Cosmetic Bench Reference, 1994 edition, pp. 27-32 and 46-48, which are incorporated herein by reference. Preferred skin softening and skin moisturizing agents are tocopherol, tocopheryl acetate, aloe, vegetable oils, mineral oil, white petrolatum, jojoba oil, and mixtures thereof. More preferably, these are encapsulated, spray dried or lyophilized. The use of encapsulated skin softening agents or these after spray-drying or freeze-drying allows to protect them by storing them in a pulverulent carrier until released by friction (such as rubbing underwear or clothing) or by contact with moisture on the skin. . Examples of preferred species of this type suitable for use in the methods of the invention are freeze-dried aloe Terra-Dry ™, freeze-dried or spray-dried aloe Terra-Pure ™ and freeze-dried aloe Terra-Spray ™, manufactured by Terry Laboratories. When skin softening or moisturizing agents are used, their concentrations are in the range of 0.1 to 50% by weight, preferably 0.1 to 25% by weight, most preferably 0.1 to 10% by weight, based on the total weight preparation.

Sliding substances

The compositions of the invention may also contain glidants. As used herein, a glidant means substances having a special structure which impart improved lubricity to the powdered substances and / or cause reduced friction of the skin at the overlapping areas of the skin.

0 · 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 00 0 0 00 »»

Glidants of the present invention are polyethylene; nylon; polytetrafluoroethylene; silica in the form of microspheres, ellipsoids, rollers and the like; mica, silicone (e.g., polydimethylsiloxane), stearic acid salts (e.g., zinc stearate), and mixtures thereof. Preferred glidants are silica in the form of microspheres, ellipsoids, rollers, and the like. Elipsoids suitable for use in the present invention are manufactured by DuPont under the trade name ZELEC®Sil. Silica microspheres are manufactured by KOBO under the designation MSS-500, MSS 500/3, MSS-500 / H, MSS-500 / 3H, MSS-500 / N, and MSS-500 / 3N. Advantageously, it is possible in the present invention to use pyrogenic silica that besides improving the lubricity of the material and supplies práškovitému increased fluidity fumed silica manufactured by Cabot Corporation (Cab-O-Sil® ¹ and Degussa (Aerosil). When glidants are used in the composition according to the invention, their concentration ranges from 0.1% to

% by weight, preferably 1 to 10% by weight, based on the total weight of the composition.

Binders

The compositions of the invention may also contain dry or wet binders which increase the adhesion of the powder and the active ingredient to the skin. Binders suitable for use in the methods of this invention are disclosed in the Cosmetic Bench Reference, 1994 edition, pp. 13-14, which is incorporated herein by reference. Preferred binder are calcium stearate, zinc stearate, isopropyl myristate, magnesium myristate, silicone and mixtures thereof. More preferred are zinc stearate, polydimethylsiloxane and mixtures thereof. If the binders are part of the preparation, their concentrations range from 0.1% to 0.1%

* · in • 9 ♦ »· • · ·· • • • · • • • • - • • • • • « • • • • • • • • • • • • ··· » · * · ·· ·· ··

% by weight, preferably 1 to 15% by weight, based on the total weight of the composition.

Antipruritics

Antipruritics may be included in the compositions of the invention. Examples of antipruritics suitable for use in the methods of the invention are the lactic acid magnesium salt, hydrocortisone, hydrocortisone acetate, and ground oatmeal. Antipruritics are described in Handbook of Non Prescription Drues, 10th Edition, p. 529, 1993, which is incorporated herein by reference. When the antipruritics are part of the preparation, their concentrations are in the range of 0.1% to 40% by weight, based on the total weight of the preparation.

Dyes

Colorants may be added to the formulations of the present invention to improve appearance. Colorants suitable for use in the body odor intensity compositions of the present invention are disclosed in the Cosmetic Bench Reference, 1994 edition, pp. 21-22, which is incorporated herein by reference.

Method of manufacture of the preparation

The compositions of the present invention are manufactured by a process comprising the following steps: preparing a mixture by admixing cyclodexin tin, high performance moisture absorbents and other ingredients in a pulverulent carrier using an industrially manufactured mixer such as a V-mixer, double-cone mixer or belt mixer until the mixture is homogeneous and reducing the particle size of the mixture using industrially manufactured equipment such as a hammer mill, impact mill, ball mill or a device in which disintegration occurs by the action of liquids until the desired particle size distribution is achieved .

Either encapsulated or free perfume may be added to the formulation in various ways. One suitable method of adding encapsulated perfume is by preparing the cyclodextrin complexes as described in U.S. Patent No. 5,429,628 to Trinh et al., Issued June 4, 1995, incorporated herein by reference, and mixing the perfume complexes. cylcodextrin with the above mixture, which is either the final or sequential preparation step. If desired, free perfume can be added by spraying a cyclodextrin, carrier, or any powdered component with the free perfume. Preferably, prior to spraying, the free perfume is mixed with one or more of the liquid ingredients of the present invention, such as skin protecting and moisturizing agents.

Since the compositions of the present invention can be applied directly to the skin or hair, various applicators are suitable for application to the whole body to achieve maximum odor control. Thus, for example, these preparations can be advantageously applied from bottles, containers, dispensers, hand-held dispensers or by means of wiping application which are brought into contact with the skin, thereby converting the preparation to the skin. Conventional bottles and containers are suitable for the application of these formulations. These bottles and containers are preferably provided with lids with small apertures for convenient application of the formulation.

The composition of the present invention may also be applied in the form of a liquid dispersion by spray applicator or from a bottle, such that upon application to the skin, the solvent immediately evaporates to form a powder coating. Examples of such suspension dosage forms are aerosols, liquid suspensions of powdery substances, or silicone suspensions.

In such aerosol formulations, the powdered substances of the present invention are usually contained in an amount corresponding to 0.1% to 15% by weight of the total weight of the formulation. The preparation of aerosols containing powders is described in more detail in U.S. Patent No. 4,078,051, Pomot et al., Issued March 7, 1978, which is incorporated herein by reference. However, this method is not suitable for use on sensitive areas of the body such as the lower abdomen and buttocks or other covered areas of the skin, as skin irritation caused by propellants commonly used in aerosol packages may occur.

Preferred is a hand-held nebulizer that delivers the formulation as a powder without the use of a propellant and in which the formulation is not in the form of a solution. Sprayers suitable for use in the methods of the present invention are described in more detail in U.S. Patent No. 2,450,205 to Rose, issued September 28, 1948, and U.S. Patent No. 2,840,277 to Bach, issued June 24, 1958, which are incorporated herein by reference. incorporated herein by reference.

Any known means for application by wiping may be used. These wiping means comprise a flexible application material. The term flexible application material as used herein refers to various types of paper, fabrics, nonwovens, foils, foams, spongy materials, rollers, pads, tissue, cellulose wipes and the like. Preferred materials for wiping compositions are porous materials such as nonwovens, foams, or spongy materials that can retain the formulation in their pores. Examples of cellulosic nonwoven materials are disclosed in U.S. Patent 4,191,609, Trokhan, issued March 4, 1980, which is incorporated herein by reference.

Combination of materials suitable for application by wiping with the compositions of the present invention is a known technique. Examples of common techniques used for this purpose are coating, dipping, dipping, sprinkling, or spraying, a material suitable for application by wiping with the compositions of the present invention. The composition of the invention is added to the material of the composition to be wiped in an amount sufficient to achieve the desired reduction in odor intensity and / or other desirable skin effect.

Any known disposable or reclosable packages are suitable for packaging the compositions of the present invention.

Methods of use

The present invention also provides a method of reducing the intensity of body odor by applying an effective amount of the disclosed compositions to the skin. It is a further object of the present invention to provide a method for reducing vaginal odor intensity by administering an effective amount of the disclosed compositions to the pelvis, outer sheath and / or lower abdomen and buttocks. However, the compositions of the present invention should not be applied to the inside of the vagina, nor to external genitalia. By an effective amount of the composition of the present invention is meant an amount sufficient to cause body odor to be absorbed to the extent that it is less recognizable by human smell. Determining the effective amount of the number of applications is left to the discretion of the user, but usually the effective amount for one application is 1 to 3 ml of the odor absorbing composition at 1 to 3 applications per day, the number of days for which the composition is used is unlimited user needs.

The compositions of the invention are applied topically directly to the skin or hair. The composition may be applied by filling it into the delivery composition and applying an effective amount of the composition by spraying, sprinkling, shaking or rubbing the composition onto the appropriate skin area, usually the entire body. Preferably, the delivery means is a container suitable for sprinkling, a spray device, or a wipe application means with a flexible delivery material.

• ·

The user may also apply the composition of the present invention to the wiping composition with the selected flexible application material. For this purpose, the user selects a flexible application material such as a cloth or wad of cotton, transfers the formulation from a bottle or other suitable container to the selected flexible application material, and applies the formulation to the appropriate body area. The user can also apply the product by hand. The user may use a greater or lesser amount of the formulation at his discretion and depending on the degree of odor reduction desired.

«·

DETAILED DESCRIPTION OF THE INVENTION

The following are perfume compositions and examples of suitable odor absorbing compositions as well as methods of using the compositions of the present invention. The perfume compositions A to G are intended for use in encapsulated form. Perfume compositions E to G may also be used as free perfumes

Perfume compositions

perfume composition AND perfume composition B component % by weight weight% component Ambrox dl 10% in DPG 1.5 benzyl acetate 2.4 benzyl acetate 1.9 cinnamalkohol 0.1 benzylsalicylate 3.1 cis-3-hexenyl acetate 0, 3 β-γ-hexenol 0.4 cis-jasmone 0, 4 cis-3-hexenyl acetate 0, 5 citronellol 4.1 cis-3-hexenylsalicylate 2, 5 citronellylacetate 1.3 acid nitrile dimethyl octanol 1, 6 citronellové 1.5 ethyllinalool 7.3 citronellol 9.2 floracetate 4.9 Cyclal C 0.9 frutén 3, 3 cyclogalbanate 0.5 geraniol 4, 9 dihydromyrcenol 0.9 Helional 4.1 Ebanol 0.1 hexylcinnamaldehyde 16, 0 eucalyptol 0, 6 hydroxycitronellal 1.6 eugenol 0.5 γ-methyl-ionone 5.7 Floracetate 8, 3 iso Super 4.1 frutén 4.0 Lyral 3, 3 geranylkyanid 0, 3 methyldihydroj asmonate 16.2 hexylcinnamaldehyde 10.5 methylphenylcarbinyl acetate 0.3 hydroxycitronellal 2, 3 P, T.Bucinal 8.9 isobornylacetate 0.2 phenylethyl alcohol 4.9 isocyklogeraniol 0, 6 phenylhexanol 0, 8 linalool 1.9 terpineol 3, 3 linalyl acetate 4.2 undecylic acid aldehyde 0, 2 methylcedrylon 0, 2 methyldihydroj asmonate 0.9 methylisobutenyltetra- hydropyran 0.3 methylphenylcarbinyl acetate 0.9 orange terpenes 17, 6

• · · · · · · · · · · · · · · ·

perfume composition A continued

component % by weight P.T.Bucinal 17, 8 phenylethyl alcohol 4.6 phenylacetate 1,2

perfume composition C perfume composition D component % by weight component % by weight 4-tert-butyl cyclohexyl - 4-tert-Butyl-cyclohexyl- acetate 10, 0 acetate 12, 3 Bacdanol 0, 5 Ambrox DL 10% in DPG 1.6 Cetalox 0.1 anisic acid aldehyde 4,5 citral 1.0 Bacdanol 0, 6 citronellol 5, 0 cis-j asmon 0.1 damascenon 0, 3 citronellol 6, 2 dihydromyrcenol 1.0 ethylcinnamate 1.3 dimethylbenzylcarbinyl ethylvanillin 1.7 acetate 1.5 eugenol 0.4 ethyl vanillin 0, 5 geraniol 12.3 geraniol 2, 0 geranyl acetate 1,2 geranylkyanid 0, 5 heliotropin 12, 3 heliotropin 5.1 hexylcinnamaldehyde 12, 3 hexylcinnamaldehyde 15, 4 methylionone 3, 5 γ-methyl-ionone 3, 2 isobornylacetate 1.7 iso Super 3, 5 isoeugenol 0, 3 Linalyl acetate 8, 1 lauric aldehyde 1,2 methylanthranilate 1.5 menthyl acetate 0.7 methyldihydroj asmonate 20, 0 methyl anthranilate 1.5 methyl-isobutenyl-tetra- methyl cinnamate 1,2 hydropyran 0.1 methylphenylcarbinyl orange terpenes 10, 0 acetate 2.7 p-methoxyacetophenone 0.4 phenyl ethyl alcohol 12.3 vanillin 10, 3 undecalactone 0.6

undecylic acid aldehyde 0.6 vanillin 6.9 «» 0 0 0 0 0 · 0 0 ♦

0 0 0 »

0 0 0 0 0 0 0 * 00

000 0 · ··

perfume composition E component % by weight citronellol 10 benzylsalicylate 15 Dec benzyl acetate 10 benzophenone 3 cedrol 2 dihydromyrcenol 10 Floracetate 5 phenylethyl alcohol 15 Dec linalyl acetate 4 linalool 6 methyl dihydro j asmonate 3 Lilial 10 phenylethyl acetate 2 c-terpineol 5

perfume composition F component % by weight benzylsalicylate 20 May benzyl acetate 15 Dec benzophenone 5 phenylethyl alcohol 10 linalool 15 Dec methyldihydroj asmonate 10 Lilial 15 Dec phenylethyl acetate 5

perfume composition G component % by weight citronellol 5 benzylsalicylate 5 benzyl acetate 5 dihydromyrcenol 5 Floracetate 5 phenylethyl alcohol 20 May linalyl acetate 5 linalool 5 Methyldihydroj asmonát 5 Lilial 20 May phenylethyl acetate 1 vanillin 6 α-terpineol 8 anisic acid aldehyde 2 Cymal 3

Examples 1 and 2

Example 1 Example 2 component % by weight component % by weight corn starch corn starch Starch) 35, 55 Starch) ............... . . .12,20 silica (micro- 10, 00 talc 10, 00 spheres) 10, 00 silica (micro- magnesium carbonate 8, 00 sphere 10, 00 synthetic silicate pyrogenic silica 5, 00 Calcium 20, 00 zinc phenolsulfonate 3, 00 pyrogenic silica 5, 00 Triclosan 0, 30 zinc phenolsulfonate 3, 00 cyclodextrin 6, 00 Triclosan 0.20 aloe vera, lyophilized 0, 50 Nylon-12 3, 00 magnesium carbonate 8, 00 zinc stearate 3, 00 Nylon-12 5, 00 β-cyclodextrin 3, 00 calcium silicate 20, 00 aloe vera, lyophilized 0.10 zinc stearate 3, 00 tocopheryl acetate (micro- tocopheryl acetate 2, 00 encapsulated) 2, 00 mineral oil 2, 00 dipropylene glycol 2, 00 polydimethylsiloxane 5, 00 free perfume ** 0, 15 encapsulated perfume * 8, 00 polydimethylsiloxane 5, 00 zeolite may also be used furthermore, <can also be used anti- a pruritic such as the 1-lactic acid salt * any encapsulated perfume composition A to G any perfume composition E to G

Examples 3 and 4

Example 3 Example 4 weight% component wt rice starch 25, 00 octenylsuccinate derivative mica 2, 00 starch 12, 40 silica, silica (ellipsoids) (ellipsoids) 14.50 (ellipsoids) 8, 00 pyrogenic silica 5, 00 pyrogenic silica 8, 00 Triclosan 0.10 zinc phenolsulfonate 7, 00 aluminum chloride hydrate 5, 00 Triclosan 0, 60 Cyclodextrin 6, 00 Cyclodextrin 10, 00 aloe vera, lyophilized 1.00 aloe vera gel / oil 1, 00

Example 3 - Continued Example 4 - Continued component % by weight component % by weight calcium carbonate 10, 00 Magnesium carbonate 7, 00 polyethylene powder 3, 00 calcium carbonate 3, 00 calcium silicate 10, 00 polyethylene powder 7, 00 zinc stearate 7, 00 calcium silicate 15, 00 polydimethylsiloxane 10, 00 zinc stearate 5, 00 encapsulated perfume * ' 1, 00 mineral oil 5, 00 free perfume ** 0, 40 polydimethylsiloxane 6, 00 encapsulated perfume * 4, 00 free perfume ** 1, 00 furthermore, i dye * any encapsulated perfume composition A to G any perfume composition E to G

Examples 5 and 6

Example 5 Example 6 component wt. % component % by weight tapioca starch 10, 00 corn starch talc 4.90 Starch) 10, 00 silica ground oatmeal 8.35 (microspheres) 20, 00 silica pyrogenic silica 2, 00 (microspheres) 5, 00 zinc oxide 4.00 silica, Triclosan 1.00 (ellipsoids) 10, 00 cyclodextrin 4, 00 pyrogenic silica 5, 00 aloe vera gel / oil 2, 00 zinc oxide 2, 00 magnesium carbonate 5, 00 Triclosan 0, 40 calcium carbonate 4, 00 cyclodextrin 5, 00 Nylon-12 10, 00 Aloe Vera Gel / Oil 2, 00 calcium silicate 15, 00 magnesium carbonate 4.00 zinc sterate 6, 00 calcium carbonate 5, 00 isopropyl myristate 4, 00 Nylon-12 4.00 polydimethylsiloxane 5, 00 Polyethylene powder 4, 00 encapsulated perfume * 3, 00 calcium silicate 10, 00 free perfume ** 0.10 zinc stearate tocopheryl acetate (microencapsulated) polydimethylsiloxane free perfume ** 10, 00 5, 00 10, 00 0.25

* any encapsulated perfume composition A to G ** any perfume composition E to G

ΦΦΦΦ φ φ · φ φ φ ΦΦ ΦΦ ΦΦ ΦΦ ΦΦ φ φ φ φ φ φ φ φ φ φ φ φ φ φ φ φ φ

Examples 7 and 8

Example 7 Example 8 component % by weight component % by weight cornstarch 6, 80 cornstarch kaolin 4, 00 Topical Starch 43.10 silica silica (microspheres) 5, 00 microspheres) 30, 00 silica zinc phenolsulfonate 3, 00 (ellipsoids) 5, 00 Triclosan 0.30 pyrogenic silica 5, 00 Nylon-12 10, 00 zinc phenolsulfonate 2, 00 β-cyclodextrin 3, 00 Triclosan 0, 20 tocopheryl acetate cyclodextrin 8.00 microencapsulated 5, 00 aloe vera gel / oil 3.00 dipropylene glycol 0, 30 magnesium carbonate 10, 00 free perfume ** 0, 30 Nylon-12 2.00 polydimethylsiloxane 5, 00 powdered polyethylene 5, 00 calcium silicate 25, 00 zinc stearate 7, 00 tocopheryl acetate microencapsulated 3, 00 isopropyl myristate 2, 00 polydimethylsiloxane 5, 00 encapsulated perfume ⁰ 2, 00 * any encapsulated parfémová compositions A to G

** any perfume composition E to G

Example 9

Example 9 component % by weight corn starch (Topical Starch) 47.50 silica (microspheres) 40, 00 Triclosan 0, 30 zinc stearate 3, 00 β-cyclodextrin 3, 00 dipropyleneglycol 0, 60 free perfume ** 0, 60 polydimethylsiloxane 5, 00

** any perfume composition E to G 999 9 9 9 9 9 9

9 9 9 9 9 99

9 9 · 9 9 9 • 99 · 9

Examples 10 and 11

Example 10 Example 11 component % by weight component % by weight cornstarch cornstarch Topical Starch 60, 80 Topical Starch 50, 00 silica talc 10, 00 (microspheres) 2, 00 silica pyrogenic silica 2.00 (microspheres) 3, 00 zinc phenolsulfonate 3, 00 pyrogenic silica 1, 00 Triclosan 0.20 zinc fenlsulfonate 3, 00 Cyclodextrin 3, 00 Triclosan 0, 30 aloe vera, lyophilized 1.00 Cyclodextrin 13, 00 Nylon-12 5, 00 aloe vera, lyophilized 0, 50 zinc stearate 7, 00 Nylon-12 5, 00 tocopheryl acetate zinc stearate 3, 00 microencapsulated 2, 00 tocopheryl acetate polydimethylsiloxane 10, 00 mi kroenkapsulovaný 2, 00 encapsulated perfume * 4.00 mineral oil 2, 00 polydimethylsiloxane 5, 00 free perfume ** 0.20 encapsulated perfume * 2, 00 further, it can also be used further, it can also be used dye zeolite. * any encapsulated perfume composition A to G any perfume composition E to G

Examples 12 and 13

Example 12 Example 13 weight% component weight% component rice starch 51,00 octenylsuccinate derivative mica 2.00 Starch (Dry Flo® Pure) 0.20 silica (ellipsoids) 2, 00 silica (ellipsoids) 4, 00 pyrogenic silica 1, 00 zinc phenolsulfonate 7.00 Triclosan 0.50 Triclosan 0, 60 aluminum chloride hydrate 5, 00 cyclodextrin 10, 00 cyclodextrin 6, 00 aloe vera gel / oil 1.00 aloe vera, lyophilized 1.00 zeolite 10, 00 powdered polyethylene 5, 00 talc 13, 60 zinc stearate 5.00 powdered polyethylene 7.00 Tocopheryl acetate oil (Vit. zinc stearate 5, 00 E. Acetate) 3, 00 mineral oil 5, 00 polydimethylsiloxane 10, 00 polydimethylsiloxane 6, 00

4 43 * ··

4 4 4 4 · · · 4 4 ·

4,444 4 4 4 4

444 4,444 44 4

4 · 4444

4444 444 44 444 44 44

Example 12 - Continued weight% component Example 13 - Continued component % by weight Nylon N-12 5.00 Free Perfume ** 0.50 Encapsulated Perfume * 3.00 free perfume ** 0, 60 a zeolite may also be used * any encapsulated perfume composition A to any perfume composition E to G G

Examples 14 and 15

Example 14 Example 15 weight% component component % by weight tapioca starch 46, 50 cornstarch talc 4, 90 Topical Starch 29, 00 silica ground oatmeal 16, 35 (microspheres) 2.50 silica pyrogenic silica 2, 00 (microspheres) 2.50 zinc oxide 4, 00 silica (ellipsoids) 1, 50 Triclosan 1.00 kaolin 8, 00 cyclodextrin 4.00 zinc oxide 2.00 Aloe Vera Gel / Oil 2, 00 Triclosan 0, 40 Nylon-12 10, 00 cyclodextrin 5, 00 zinc stearate 6, 00 aloe vera gel / oil 2.00 isopropyl myristate 4, 00 Nylon-12 4, 00 polydimethylsiloxane 5, 00 powdered polyethylene 4.00 free perfume ** '· 0.10 zinc stearate 10, 00 encapsulated perfume * 8, 00 tocopheryl acetate microencapsulated polydimethylsiloxane free perfume ** 5, 00 10, 00 0.25

* any encapsulated perfume composition A to G “any perfume composition E to G” 9999 999 99 999 9 · 99

Example 16 Example 16

component % by weight corn starch (Topical Starch) 49, 00 kaolin 14.50 silica (microspheres) 2, 50 silica (ellipsoids) 1.50 pyrogenic silica 0, 50 zinc phenolsulfonate 2, 00 Triclosan 0.20 cyclodextrin 8, 00 aloe vera gel / oil 3, 00 Nylon-12 2, 00 powdered polyethylene 5, 00 tocopheryl acetate microencapsulated 3, 00 isopropyl myristate 2, 00 polydimethylsiloxane 5, 00 free perfume ** 0, 80 encapsulated perfume * 1, 00 * any encapsulated perfume composition

any perfume composition E to G

The compositions of the above examples are prepared as follows: First, the cyclodextrin, the solids, and the powdered carrier are mixed using an industrial mixer such as a V-mixer, a double-cone mixer or a belt mixer until the mixture is homogeneous, and then the particle size of this mixture is reduced by the use of crushing / grinding devices such as a hammer crusher, impact mill, ball mill, or device in which the disintegration is effected by the energy of the flowing liquid. An additional mixture is prepared from this mixture by the addition of liquid skin softening agents, skin moisturizers, and / or skin protection agents, wherein a more uniform particle size distribution is preferably achieved using spray atomization with stirring. The mixture thus obtained can then, if necessary, be subjected to further grinding / crushing and optionally pneumatic size sorting. If it is a constituent of preparations, it shall indicate34 fl ♦

··· ·

• ·

9 ·

9 9

In the previous examples of free perfume, the liquid phase added to the original solids mixture may comprise a perfume composition. If the ingredients of the compositions of the foregoing examples of the invention are encapsulated perfume, the encapsulated perfume may be one of the solid components that are mixed in the first step, or may preferably be added after the liquid substances have been added to the mixture.

Preparations for application to the skin: The formulations of the present invention, such as those mentioned in the preceding examples, may be transferred to the wiping agent or filled into a spray device or container. The compositions may be applied to the skin directly, or by a flexible delivery device selected by the user so that the composition can be conveniently applied to the skin. The wiping composition is prepared by coating, sprinkling, or spraying the composition onto a dry flexible delivery device, which is carried out until the desired degree of coating or layer thickness of the composition on the flexible delivery device is achieved. For spray application, the formulation is filled into a container of the selected spray applicator. The vial is closed and the spray applicator is stored until use. To prepare an aerosol spray requiring pressure, the formulation is transferred to a suitable container. The vial is pressurized by adding the propellant and sealed.

Example 17

In a woman suffering from stress incontinence, the urine released in this disease caused a vaginal odor which had to be eliminated or reduced. Wiping the outer sheath and pelvis area • 4 ·· 4 4 · 44

4 4 4 4 43 4

4 4 4 4 4 5

4 44 44 4

4,444,444

4444 444 44 444 44 44 after release of urine with a swab containing the preparation of Example 10, this woman achieved a reduction in vaginal odor.

Example 18

In an obese woman with large breasts, sweating and skin irritation under the breasts occurred during physical exercises. This woman applied the preparation of Examples 3 or 9 before and after physical exercises by applying it to the areas of the skin under the breasts by hand spray applicators before and after exercising. The woman also applied these preparations to the skin in the areas of the folds of the abdomen skin, as well as to other such covered areas of the skin susceptible to inflammation. The use of powder formulations in this manner has resulted in reduced body odor and reduced perspiration on the skin.

Example 19

A man who hated the use of cosmetic deodorants, sweating suppressants and colognes due to severe allergies developed uncontrolled and unpleasant body odor. The doctor recommended that he use a mild, slightly perfumed, odor-absorbing preparation, according to Example 1 or 15, after taking a shower. Each morning after taking a shower, the man applied one of these preparations to the entire body by spraying without causing an allergic reaction. This relieved the man of the trouble of a fierce and uncontrollable body odor.

If repeated daily dosing was required, the man carried swabs with the formulation of Example 1 or 10.

Claims (13)

1. An odor absorbing preparation comprising: a) 0.1% to 25% by weight of uncomplexed cyclodextrin, b) a perfume composition selected from the group consisting of encapsulated perfume which is present in the composition at a concentration of 0.05% to 15% by weight, and a free perfume which is present at the concentration of 0.01 to 5% by weight. and mixtures thereof; and c) a powder carrier, wherein said encapsulated perfume comprises one or more volatile perfume components having a boiling point below 260 ° C and whose components have a considerably low odor threshold. The composition of claim 1, further comprising 5 to 60 wt% of a high performance moisture absorbent. The composition of claim 2, wherein said highly effective moisture absorbents are selected from the group consisting of silicates, silica, and carbonates. Composition according to any one of the preceding claims, characterized in that the cyclodextrin is selected from the group consisting of β-cyclodextrin, β-cyclodextrin derivatives, α-cyclodextrin, α-cyclodextrin derivatives, γ-cyclodextrin, γ-cyclodextrin derivatives and mixtures thereof . A composition according to any preceding claim, wherein the particle size is 1 µm to 100 µm. A formulation according to any one of the preceding claims, wherein the particle size of the cyclodextrin is 1 µm to 12 µm. ΒΒΒΒ • Β Β ΒΒ ΒΒΒ ΒΒ Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β Β ΒΒ ΒΒ Composition according to any one of the preceding claims, characterized in that it may contain other ingredients selected from the group consisting of zeolites, activated carbon, sodium bicarbonate, bacteriostats, antiperspirants, skin protectants, skin softening agents, skin moisturizers and glidants . A preformed wiping composition, characterized in that a composition according to any one of the preceding claims is applied to the composition comprising a flexible application material. A composition according to any one of the preceding claims, characterized in that it is applied in the form of a powder by means of a hand-held sprayer. Use of the compositions of any of the preceding claims as odor and moisture absorbent compositions that are safe for use on the skin to reduce the intensity of body and / or vaginal odor. Use according to claim 10, wherein the preparation is applied in the region of the pelvis, outer sheath, and / or lower abdomen and buttocks. Use according to claim 10 or 11, wherein the composition is applied to the skin using a hand-held sprayer. 13. A method of making a composition for absorbing odor and moisture comprising: (a) preparing the first mixture by mixing the powdered carrier, the high performance moisture absorbent and the cyclodextrin in an industrial mixer until the mixed mixture is homogeneous; b) reducing the particle size of the mixture by applying an industrial process suitable for reducing the particle size to said first mixture until a desired particle size distribution is achieved; • · c) preparing the perfumed powdered composition by sprinkling the reduced particle size composition with free perfume and mixing.