CZ27862U1 - Nutritive cosmetic composition - Google Patents

Description

The technical solution concerns a nutritional cosmetic preparation based on dried Jerusalem artichoke tubers and burnt out brewing yeast.

BACKGROUND OF THE INVENTION

Nutritional cosmetics for internal use used to restore hair and nails using substances that activate metabolism and thus promote hair and nail growth are widely available on the market and are recommended for use even if the damage is due to physical or chemical trauma.

These are complex preparations usually containing the following groups of bioactive substances:

- amino acids (cysteine, methionine),

- minerals (potassium, silicon, calcium and magnesium) and trace elements (iron, zinc, copper and phosphorus), and

- vitamins (B vitamins, pantothenic acid, paraaminobenzoic acid).

Nutritional cosmetics very often use natural substances or extracts from natural substances, such as nettle, horsetail, millet, wheat, yeast.

However, some natural substances and their extracts may cause allergies. There remains a need to find suitable sources of bioactive substances for nutritional cosmetic use that would also be suitable for consumers who, for whatever reason, cannot use the preparations available so far.

The essence of the technical solution

Disadvantages of the prior art are solved by a new, biologically suitable source of bioactive substances, which are sparingly dried Jerusalem artichoke tubers or grape marc obtained after the juice has been squeezed or water-grated tubers are extracted.

The subject of the technical solution is a nutritional cosmetic product, especially suitable for restoring and improving the condition of hair and nails, which contains dried material from Jerusalem artichoke tubers and dried brewer's yeast.

Jerusalem artichokes have a high content of oligofructans and inulin, which form soluble fiber in the preparations, increasing the bioavailability of calcium and magnesium in particular. The silicon content of Jerusalem artichoke tubers is also surprisingly higher than the silicon content of traditionally used extracts of nettle or horsetail. Also important for nutritional cosmetics is the significant content of simy amino acids in the protein component of Jerusalem artichoke tubers. The combination of spray-dried and burnt-out brewer's yeast with Jerusalem artichokes brings a significant proportion of B-group vitamins in their natural form to nutritional cosmetics.

Dried tompinambur tuber material means dried and ground or crushed Jerusalem artichoke tubers, so-called Jerusalem artichoke flour, or grape marc resulting from the juice squeezing or elimination of water-grated tubers.

The dried brewer's yeast is preferably burned. This may be, for example, spray-dried, burnt out brewing yeast.

The weight ratio of Jerusalem artichoke material and brewer's yeast in the formulation is preferably 1:10 to 10: 1, more preferably 1: 5 to 5: 1, most preferably 1: 3 to 3: 1.

In a preferred embodiment, the nutritional composition is in the form of tablets or two-piece capsules with walls containing materials derived from plant sources such as hypromellose (HPMC), pullulan and the like. The tablets preferably have a core weight of 350 to 950 mg. preferably a nominal cavity volume of 0.7 to 0.9 ml, preferably the capsules have an acid-resistant finish.

HPMC capsules have a low moisture content compared to gelatin capsules and can also be dried because the water does not function as a plasticizer. Hypromellosis also does not cross the gelatin capsule wall and hence accelerated stability tests (6 months at 40 ° C and 75% relative humidity). humidity) there are no changes in the release of the contents. HPMC capsules are mainly seen as a vegetable substitute for gelatin of animal origin. A substantially lower water content of the capsule (4 wt.% To 6 wt.%) Compared to 13 wt.% Also plays a role in the filling and sealing of liquid cartridges in HPMC capsules. % to 16 wt. % water in gelatin capsule. Tzv. Capsugel's DRcaps ™ are innovative gellanin-containing HPMC capsules that protect dietary supplements from stomach acidity and also mask unpleasant flavors and odors, and begin to disintegrate approximately 45 minutes later than typical capsules, with immediate release in about 5 minutes. Studies show that complete release occurs in the intestine.

Pullulan-based capsules have a similar moisture content to gelatin capsules. The capsules made of pullulan (60 to 99% by weight) generally contain polyol-based plasticizers (glycerol, propylene glycol, sorbitol, and maltitol). The most widespread type of pullulan capsules available on the European market are Capsugel NPcaps® capsules containing, in addition to pullulan, also carrageenan, and potassium chloride. The advantage of these capsules is their low oxygen permeability wall, which is only 1/8 of the gelatin capsule wall permeability.

Jerusalem artichoke tubers do not contain gluten, so their use is suitable for celiacs. They contain pectin substances which allow compression into tablets without the need for additional excipients to ensure tablet cohesion.

Jerusalem artichoke tubers and brewer's yeast naturally contain much of the necessary bioactive substances for nutritional cosmetics. However, other bioactive substances may be added to the preparation or, by adding bioactive substances, their content may be increased compared to the natural content in Jerusalem artichoke and yeast. For example, methionine, cysteine, cystine, taurine, pantothenic acid or a salt thereof, nicotinamide, biotin, and fillers such as magnesium stearate or talc may be added.

Examples of technical solutions

Example 1

Tablet composition for 1000 pcs:

Jerusalem artichoke, dried marc 250,00 g

Dried brewer's yeast 100,00 g

L-methionine 50.00 g

Calcium pantothenate 50.00 g

Carrier F-Melt type C 97,80 g

Magnesium stearate_2,20 g

Total amount 550,00 g

Tablets were prepared by mixing the ingredients and compressing the mixture in a tablet machine. Active ingredients in 1 tablet weighing 550 mg:

Calcium pantothenate 50.0 mg / tbl

L-methionine 50.0 mg / tbl

Niacin 43.0 pg / tbl

-2EN 27862 Ul

Thiamin

Riboflavin

7.0 pg / tbl 7.0 pg / tbl

Mineral substances from Jerusalem artichoke from brewer's yeast Σ Potassium 45.9 mg / tbl + 1.8 mg / tbl 4Ί, Ί mg / tbl Silicon 6,6 mg / tbl ... 6,6 mg / tbl Calcium 1.7 mg / tbl + 0.3 mg / tbl 2.0 mg / tbl Magnesium 1.6 mg / tbl ... 1.6 mg / tbl Phosphorus 0.8 pg / tbl + 1.1 mg / tbl 1,1 mg / tbl Iron 14.7 pg / tbl + 7.0 pg / tbl 21.7 pg / tbl Zinc 3.0 pg / tbl + 5.0 pg / tbl 8,0 pg / tbl Copper - + 0.5 pg / tbl 0.5 pg / tbl

Example 2 Tablet composition for 1000 pcs: Jerusalem artichoke, dried (flour) 100,00 g Dried brewer's yeast 100,00 g L-methionine 125,00 g L-Cysteine 25,00 g Calcium pantothenate 50,00 g Nicotinamide 4,00 g D-biotin 0,03 g Magnesium stearate 2,20 g The total amount of 406.23 g Example 3 Filling composition for 1000 pcs of two-part capsules: Jerusalem artichoke, dried marc (flour) 100,00 g Dried brewer's yeast 100,00 g L-methionine 125,00 g L-Cysteine 25,00 g Calcium pantothenate 50,00 g Nicotinamide 4,00 g D-biotin 0,03 g Magnesium stearate 2,20 g Total amount of capsule filling 406.23 g

The ingredients were mixed and filled into HPMC capsules.

-3GB 27862 U1

Example 4: Preparation and specification of Jerusalem artichoke flour

Flour was obtained by mechanical processing of dried grape marc after squeezing the juice from the tubers of Jerusalem artichoke (Helianthus tuberosus (L.)).

The reported values come from the Běloslupka varieties. Karina. Lola and Fertile.

Exam Specifications 1. Description White-gray powder, characteristic, herbal aroma, pleasant sweetish taste, free of fungal odor and foreign flavors 2. Loss on drying Not more than 7% 3. Ash content Not more than 5% 4. Particle size Leave at least 95% of the weight of the weighed screen through a 0,125 mm sieve 5. Dietary fiber content 5.1 ± 0.9% 6. Protein content 10.0-11.1% in dry matter 7.0Inulin content 34.4 - 36.4% in dry matter 8.0Gluten content absent 9. Heavy metal content: CD Pb <1.00 mg / kg <0.10 mg / kg

Hg As <0.05 mg / kg <0.10 mg / kg 10.Microbial pollution Total number of microorganisms Not more than 10 ⁵ cfu / g Bacilus cereus Not more than 10 ⁴ cfu / g Fungi Not more than 10 ³ cfu / g Yeast Not more than 10 ² cfu / g Potentially toxicogenic fungi Not more than 10 ² cfu / g Coliform bacteria Not more than 10 ² cfu / g Escherichia coli Absence in 1 g Salmonella Absence in 10 g Staphylococcus aureus Absence in 1 g Listeria monocytogenes Not more than 100 cfu / g

-4GB 27862 U1

Average nutritional values:

Energy value in 100 g dry matter 530.4 - 647.6 kJ Carbohydrates 42.45 - 48.19% in dry matter of which sugars (sucrose, glucose glucose) 136-201 kJ inulin 34.45 - 36.36% in dry matter 217 - 229 kJ sucrose 4.23 - 5.27% in dry matter glucose <0.27% in dry matter fruktoza 3.50 - 6.29% in dry matter Organic nitrogen (org.N x 6.38 = proteins) 10.0-11.1% (dry weight) 170-188 kJ Fats (as ether extract) 0.5 ± 0.3% 7.4 - 29.6 kJ Mineral substances: Loss on drying Ash Potassium Magnesium Phosphorus Silicon Calcium 4.6-5.2% (v / v) 4.1-4.4% (v / v) 1.75- 1.87 g / 100 g dry matter 590 - 645 mg / 100 g dry matter 0.28-0.31% (v / v) 1.71- 3.69 g / 100 g dry matter 1.52 - 1.83 g / 100 g dry matter

PROTECTION REQUIREMENTS

Claims (4)

PROTECTION REQUIREMENTS 1. Nutraceutical product, especially suitable for restoring and improving the condition of hair and nails, 5, characterized in that it comprises dried Jerusalem artichoke tuber material and dried brewer's yeast. Nutraceutical composition according to claim 1, characterized in that the weight ratio of Jerusalem artichoke material and brewer's yeast in the composition is 1:10 to 10: 1, more preferably 1: 5 to 5: 1, most preferably 1: 3 to 3: 1. Nutraceutical composition according to any one of the preceding claims, characterized in that it is in the form of tablets or in the form of two-piece capsules, preferably capsules with walls containing hypromellose or pullulan. Nutritional cosmetic composition according to any one of the preceding claims, characterized in that it contains further bioactive substances selected from the group comprising methionine, cysteine, 15 cystine, taurine, pantothenic acid or a salt thereof, nicotinamide, biotin.