JPH0967269A - Fruit body tablet of grifola frondosa s. f. gray - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a fruit body tablet of Grifola frondosa S. F. Gray capable of expecting stable effects. SOLUTION: This fruit body tablet of Grifola frondosa S. F. Gray is obtained by mixing a dried powder of the fruit body of the Grifola frondosa S. F. Gray with a β-glucan extracted from a dried material of the fruit body of the Grifola frondosa S. F. Gray. The tablet contains 85wt.% fruit body powder of the Grifola frondosa S. F. Gray, 10wt.% extract containing >=80% β-glucan and the balance of a stabilizer for the tablet. In the fruit body powder of the Grifola frondosa S. F. Gray, 5wt.% is substituted with vitamin C.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a tablet in which β-glucan, which is often contained in fruiting bodies of Maitake, is reinforced and blended.

[0002]

Conventionally, fruiting bodies of Maitake mushrooms, which are mushrooms, contain a relatively large amount of β-glucan, and this β-glucan is said to have an anticancer action.
In order to use this, the fruiting body of Maitake is dried and crushed into a powder, which is provided as a drug.

However, the content of β-glucan contained in fruiting bodies of Maitake mushrooms varies from individual to individual, and varies greatly depending on cultivation conditions and production lots. That is, the fluctuation range of the content is 8%
From 20% to 2.5 times. Therefore, even if it is generally provided as a drug, the dose is not constant, so that reliable drug efficacy cannot be expected.

[0004] By the way, in order to obtain an anti-cancer effect by β-glucan, it is said that 4 to 6 g of maitake powder must be ingested per day. However, as described above, the β-glucan contained in the fruit body of Maitake is not constant depending on the individual, and even if 4 to 6 g of Maitake powder is ingested, the required amount of β-glucan cannot always be taken. Further, even if the fruiting body of Maitake mushrooms contains an appropriate amount of β-glucan, if 5 g is ingested per day, 20 tablets must be taken as 250 mg tablets, which causes pain.

The present invention solves the above-mentioned problems associated with the current intake of Maitake fruiting bodies, and an object thereof is to provide Maitake fruiting body tablets which can be expected to have a stable effect.

[0006]

In order to achieve the above-mentioned object, the present invention employs a means of mixing dry powder of Maitake fruit body with β-glucan extracted from the dried product of Maitake fruit body. . Also, as a tablet ingredient, 85% by weight of Maitake mushroom body powder and β-glucan 80
The extract containing 10% by weight or more was 10% by weight, and the rest was a tablet stabilizer. Furthermore, 5% by weight of Maitake mushroom body powder
It was also decided to selectively use the means of substituting V for vitamin C.

[0007] Maitake mushroom fruit body is said to be effective in its components for anti-cancer, anti-obesity, blood sugar level control, blood pressure lowering, cholesterol level lowering, constipation, etc. In particular, β-glucan in the components is It is specified as the active ingredient. Therefore, it is possible to effectively function in these cases by ingesting a proper amount of fruiting body of Maitake.
By the way, since the content of β-glucan in Maitake fruit bodies varies depending on individual differences in Maitake, β-glucan extracted from Maitake fruit bodies is required in order to ensure a somewhat uniform content.
A glucan extract is added as a supplement. 8 beta glucans
The reason why the extract containing 0% or more is used is to stabilize the drug efficacy value of the tablet in a high portion.

Vitamin C has the effect of promoting the absorption of β-glucan into the body, thus reinforcing the basic effect as an agent.

Regarding toxicity including acute toxicity, there is no problem because the basic composition of the tablet of the present invention is dried maitake mushroom, which has been used for food since ancient times. In addition, since β-glucan, which is a reinforcing component, is also extracted from fruit bodies of Maitake mushrooms, there is no problem. The same applies to vitamin C.

The dosage form is preferably in the form of a tablet so that the dosage can be easily confirmed. The dose varies depending on the weight and condition of the individual who ingests it, so it cannot be specified, but the range is 2 to 4 g per day.
Take as appropriate. For example, for a 250 mg tablet, 1
Take 8 to 16 tablets daily or in several divided doses. Since there is no risk of side effects or fulminant effects on the digestive system, it can be taken on an empty stomach or a full stomach.

[0011]

EXAMPLE The dried powder of Maitake mushroom body according to the present invention was obtained by drying Maitake mushrooms with hot air and then pulverizing them to obtain a powder. Next, as a method for extracting β-glucan, a dried powder of Pleurotus cornucopiae fruiting body was subjected to pressurized hot water extraction with fresh water at 100 to 120 ° C, and the supernatant was concentrated under reduced pressure to obtain a concentrated solution. Then, further concentrate by ethanol fractionation,
A powder was obtained as a dried product. Beta glucan content ratio of 80
The means for adjusting the weight percentage was the ethanol fractionation step. In the present invention, it is not necessary to completely isolate β-glucan, and the object can be achieved by setting the content ratio to 80% by weight or more, so the rest was not identified.
Moreover, since the extracted mother body is edible Maitake mushrooms, there is no problem with toxicity.

[0012] 80% by weight of the dried powder of fruiting body of Maitake and the extracted powder of β-glucan of 10
To 5% by weight of vitamin C powder, 5% by weight of vitamin C was added, 3% by weight of sucrose fatty acid ester and 2% by weight of silicon dioxide were added as stabilizers of the tablet, and after uniformly mixing, tablets were formed with a tablet machine. completed. Since this component contains vitamin C, absorption of β-glucan into the body is promoted.

On the other hand, in the case of tablets containing no vitamin C, vitamin C obtained by omitting dry powder of Maitake mushroom fruit bodies is used.
It is sufficient to increase the amount by the weight ratio of the above, and the tablet manufacturing method is the same as the above-mentioned embodiment.

[0014]

INDUSTRIAL APPLICABILITY In the present invention, the β-glucan extract is supplementarily added to the dried powder of fruiting body of Maitake mushroom, so that the active ingredient can be stably added to the tablet. Further, since those having enhanced vitamin C promote the absorption of β-glucan into the body, the effect can be expected further.

Claims (3)

[Claims] 1. A maitake fruiting body tablet comprising a dried powder of a fruiting body of maitake and β-glucan extracted from a dried product of a fruiting body of maitake. 2. A maitake fruit body powder is used as a tablet component.
The maitake fruiting body tablet according to claim 1, wherein the extract contains 5% by weight and 80% or more of β-glucan is 10% by weight, and the balance is a tablet stabilizer. 3. The Maitake mushroom body tablet according to claim 2, wherein 5% by weight of the Maitake fruit body powder is replaced with vitamin C.