CY667A - Cephalosporanic acid derivatives and a process for the preparation thereof - Google Patents

Cephalosporanic acid derivatives and a process for the preparation thereof

Info

Publication number
CY667A
CY667A CY66772A CY66772A CY667A CY 667 A CY667 A CY 667A CY 66772 A CY66772 A CY 66772A CY 66772 A CY66772 A CY 66772A CY 667 A CY667 A CY 667A
Authority
CY
Cyprus
Prior art keywords
preparation
acid derivatives
cephalosporanic acid
cephalosporanic
derivatives
Prior art date
Application number
CY66772A
Other languages
English (en)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of CY667A publication Critical patent/CY667A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/32—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an araliphatic carboxylic acid, which is substituted on the aliphatic radical by hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/58—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with a nitrogen atom, which is a member of a hetero ring, attached in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CY66772A 1965-11-24 1972-12-13 Cephalosporanic acid derivatives and a process for the preparation thereof CY667A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US509627A US3303193A (en) 1965-11-24 1965-11-24 Derivatives of cephalosporanic acid

Publications (1)

Publication Number Publication Date
CY667A true CY667A (en) 1972-12-13

Family

ID=24027438

Family Applications (1)

Application Number Title Priority Date Filing Date
CY66772A CY667A (en) 1965-11-24 1972-12-13 Cephalosporanic acid derivatives and a process for the preparation thereof

Country Status (13)

Country Link
US (1) US3303193A (ja)
BE (1) BE689995A (ja)
BR (1) BR6684800D0 (ja)
CH (1) CH477476A (ja)
CY (1) CY667A (ja)
DE (1) DE1670163C3 (ja)
DK (1) DK112944B (ja)
ES (1) ES333664A1 (ja)
FR (2) FR1516019A (ja)
GB (1) GB1162247A (ja)
MY (1) MY7300189A (ja)
NL (2) NL6616444A (ja)
SE (1) SE348203B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4061862A (en) * 1975-10-06 1977-12-06 Bristol-Myers Company Derivatives of 7-(cyclized)phenylglycyl-3-triazolo-thio methyl cephalosporin
US4064345A (en) * 1975-12-12 1977-12-20 Bristol-Myers Company Cephalosporins derivatives 7-cyclized α-amino-3-heterothio
US4002748A (en) * 1976-01-19 1977-01-11 Eli Lilly And Company Method of preparing sterile essentially amorphous cefazolin for reconstitution for parenteral administration
JPS54112892A (en) * 1978-02-23 1979-09-04 Shionogi & Co Ltd Substituted imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid
US4288590A (en) * 1980-02-14 1981-09-08 Bristol-Myers Company 7-[Dα-(4-Hydroxy-1,5-naphthyridine-3-carboxamido)-α-arylacetamido]-3-(N,N-dimethyl-aminomethylpyridinium) methyl-3-cephem-4-carboxylates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2985648A (en) * 1958-10-06 1961-05-23 Doyle Frank Peter Alpha-aminobenzylpenicillins
GB985747A (en) * 1961-09-11 1965-03-10 Lilly Co Eli Cephalosporin compounds
US3198804A (en) * 1963-01-25 1965-08-03 Bristol Myers Co alpha-aminomethylpenicillin derivatives

Also Published As

Publication number Publication date
NL125838C (ja)
GB1162247A (en) 1969-08-20
FR6118M (ja) 1968-06-17
US3303193A (en) 1967-02-07
BE689995A (ja) 1967-05-22
DE1670163A1 (de) 1970-08-13
MY7300189A (en) 1973-12-31
SE348203B (ja) 1972-08-28
ES333664A1 (es) 1967-12-01
DK112944B (da) 1969-02-03
DE1670163B2 (de) 1973-04-26
BR6684800D0 (pt) 1973-12-18
CH477476A (de) 1969-08-31
FR1516019A (fr) 1968-03-08
NL6616444A (ja) 1967-05-25
DE1670163C3 (de) 1973-11-29

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