CY558A - Cyano-acylated cephalosporin derivatives and process for their manufacture - Google Patents

Cyano-acylated cephalosporin derivatives and process for their manufacture

Info

Publication number
CY558A
CY558A CY55870A CY55870A CY558A CY 558 A CY558 A CY 558A CY 55870 A CY55870 A CY 55870A CY 55870 A CY55870 A CY 55870A CY 558 A CY558 A CY 558A
Authority
CY
Cyprus
Prior art keywords
cyano
manufacture
cephalosporin derivatives
acylated cephalosporin
acylated
Prior art date
Application number
CY55870A
Other languages
English (en)
Original Assignee
Ciba Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Ltd filed Critical Ciba Ltd
Publication of CY558A publication Critical patent/CY558A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/28Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an aliphatic carboxylic acid, which is substituted by hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CY55870A 1965-01-18 1970-08-19 Cyano-acylated cephalosporin derivatives and process for their manufacture CY558A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH67565A CH480365A (de) 1965-01-18 1965-01-18 Verfahren zur Herstellung neuer Derivate der 7-Aminocephalosporansäure
CH450365 1965-04-01
CH647365 1965-05-10
CH1449365A CH507292A (de) 1965-01-18 1965-10-20 Verfahren zur Herstellung von Derivaten der 7-Amino-cephalosporansäure

Publications (1)

Publication Number Publication Date
CY558A true CY558A (en) 1970-08-19

Family

ID=27427960

Family Applications (1)

Application Number Title Priority Date Filing Date
CY55870A CY558A (en) 1965-01-18 1970-08-19 Cyano-acylated cephalosporin derivatives and process for their manufacture

Country Status (14)

Country Link
US (1) US3483197A (US08066781-20111129-C00013.png)
AT (1) AT266317B (US08066781-20111129-C00013.png)
BE (1) BE675221A (US08066781-20111129-C00013.png)
BR (1) BR6676490D0 (US08066781-20111129-C00013.png)
CH (3) CH480365A (US08066781-20111129-C00013.png)
CY (1) CY558A (US08066781-20111129-C00013.png)
DE (1) DE1670324B2 (US08066781-20111129-C00013.png)
DK (1) DK126256B (US08066781-20111129-C00013.png)
ES (1) ES321847A1 (US08066781-20111129-C00013.png)
FR (5) FR1463651A (US08066781-20111129-C00013.png)
GB (1) GB1109525A (US08066781-20111129-C00013.png)
IT (1) IT1049252B (US08066781-20111129-C00013.png)
NL (1) NL148611B (US08066781-20111129-C00013.png)
SE (1) SE359840B (US08066781-20111129-C00013.png)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759570A (fr) * 1969-11-28 1971-05-27 Ciba Geigy Derives de l'acide 7-cyanacetylamino-cephalosporanique et procede pour leur preparation
CS165353B2 (US08066781-20111129-C00013.png) * 1969-12-18 1975-12-22
GB1350772A (en) * 1971-01-27 1974-04-24 Merck & Co Inc Antibiotics and processes for their production
US3855212A (en) 1972-08-04 1974-12-17 Squibb & Sons Inc Cyanomethylth ioacetylcephalosporins
US3932396A (en) * 1972-08-04 1976-01-13 E. R. Squibb & Sons, Inc. Cyanomethylthioacetylcephalosporins
US3932397A (en) * 1972-08-04 1976-01-13 E. R. Squibb & Sons, Inc. Cyanomethylthioacetylcephalosporins
US3915964A (en) * 1973-06-18 1975-10-28 American Home Prod 6 and 7-(2-cyano-2-cyclohexylacetamido)penicillanic and cephalosporanic acids
US4061853A (en) * 1975-12-09 1977-12-06 Ciba-Geigy Corporation Virtually solvent-free crystal form of the sodium salt of Cephacetril
MD226C2 (ro) * 1976-03-25 1995-11-30 Roussel Uclaf, Societe Anonyme Procedeu de obtinere a derivatilor acidului 7-(2-(2-aminotiazolil-4)-2-alcoxiiminoacetamido)-3-cefem-4-carbonic
US4089453A (en) * 1976-04-30 1978-05-16 Reynolds Metals Company Soldered tube end
US4198504A (en) * 1978-11-02 1980-04-15 Bristol-Myers Company [3-(Pyridinium)-7-(naphthyiridinyl carbonylamino)acetamido]cephalosporanic acid derivatives
EP0113245B1 (en) * 1982-12-29 1989-03-15 Kureha Kagaku Kogyo Kabushiki Kaisha Cephalosporin derivatives
CN102898439B (zh) * 2011-07-27 2015-03-25 广东立国制药有限公司 一种去乙酰头孢呋辛内酯的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3222362A (en) * 1961-08-23 1965-12-07 Lilly Co Eli Arylaminoalkyl cephalosporins

Also Published As

Publication number Publication date
FR5318M (US08066781-20111129-C00013.png) 1967-08-21
NL6600586A (US08066781-20111129-C00013.png) 1966-07-19
CH507292A (de) 1971-05-15
FR5300M (US08066781-20111129-C00013.png) 1967-08-16
IT1049252B (it) 1981-01-20
AT266317B (de) 1968-11-11
BR6676490D0 (pt) 1973-09-06
ES321847A1 (es) 1967-01-01
CH480365A (de) 1969-10-31
FR5298M (US08066781-20111129-C00013.png) 1967-08-16
US3483197A (en) 1969-12-09
FR5299M (US08066781-20111129-C00013.png) 1967-08-16
DE1670324B2 (de) 1977-03-10
CH542236A (de) 1973-11-15
BE675221A (US08066781-20111129-C00013.png) 1966-07-18
DK126256B (da) 1973-06-25
FR1463651A (fr) 1966-12-23
SE359840B (US08066781-20111129-C00013.png) 1973-09-10
DE1670324A1 (de) 1970-10-29
GB1109525A (en) 1968-04-10
NL148611B (nl) 1976-02-16

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