CY535A - Pyrazinamidoguanidines - Google Patents

Pyrazinamidoguanidines

Info

Publication number
CY535A
CY535A CY53570A CY53570A CY535A CY 535 A CY535 A CY 535A CY 53570 A CY53570 A CY 53570A CY 53570 A CY53570 A CY 53570A CY 535 A CY535 A CY 535A
Authority
CY
Cyprus
Prior art keywords
pyrazinamidoguanidines
Prior art date
Application number
CY53570A
Other languages
English (en)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CY535A publication Critical patent/CY535A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CY53570A 1962-10-30 1970-04-10 Pyrazinamidoguanidines CY535A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23421362A 1962-10-30 1962-10-30
US311291A US3300494A (en) 1962-10-30 1963-09-27 Pyrazinamidoguanidine products

Publications (1)

Publication Number Publication Date
CY535A true CY535A (en) 1970-04-10

Family

ID=26927676

Family Applications (1)

Application Number Title Priority Date Filing Date
CY53570A CY535A (en) 1962-10-30 1970-04-10 Pyrazinamidoguanidines

Country Status (12)

Country Link
US (1) US3300494A (pt)
BE (1) BE639393A (pt)
BR (1) BR6353917D0 (pt)
CH (2) CH454879A (pt)
CY (1) CY535A (pt)
DE (1) DE1470052A1 (pt)
DK (2) DK108864C (pt)
FR (1) FR1552762A (pt)
GB (2) GB1067474A (pt)
MY (1) MY7000080A (pt)
NL (1) NL299929A (pt)
SE (3) SE334614B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE639386A (pt) * 1962-10-30
NL6501301A (pt) * 1964-04-03 1965-10-04
US3455919A (en) * 1966-09-01 1969-07-15 Merck & Co Inc 5-dechlorination of 3-amino-5,6-dichloropyrazinoyl compounds
US3507865A (en) * 1967-04-27 1970-04-21 Merck & Co Inc 3-hydroxy- and 3-mercaptopyrazinamidoguanidines the corresponding ethers and thioethers and processes for their preparation
US3539569A (en) * 1968-08-21 1970-11-10 Merck & Co Inc Preparation of pyrazinoylguanidines from pyrazinoylureas
US4085211A (en) * 1975-12-15 1978-04-18 Merck & Co., Inc. Pyrazinecarboxamides and processes for preparing same
US4087526A (en) * 1976-07-23 1978-05-02 Merck & Co., Inc. (3-Amino-5-substituted-6-fluoropyrazinoyl or pyrazamido)-guanidines and their derivatives bearing substituents on the guanidino nitrogens
US4224447A (en) * 1979-03-27 1980-09-23 Merck & Co., Inc. Novel pyrazinecarboxamides and processes for preparing same
US4604394A (en) * 1984-10-01 1986-08-05 Merck & Co., Inc. Antiarrhythmic compositions and method
GB8903592D0 (en) * 1989-02-16 1989-04-05 Boots Co Plc Therapeutic agents
IN172842B (pt) * 1990-05-17 1993-12-11 Boots Pharmaceuticals Limited
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6903105B2 (en) * 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
US20070021439A1 (en) * 2005-07-25 2007-01-25 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens with soluble amide and ester pyrazinoylguanidine sodium channel blockers
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
BR112015014178A2 (pt) 2012-12-17 2017-07-11 Parion Sciences Inc compostos de 3,5-diamino-6-cloro-n-(n-(4-fenilbutil)carbamimidoil) pirazina-2- carboxamida
PT2931713T (pt) 2012-12-17 2017-02-22 Parion Sciences Inc Derivados de cloro-pirazina carboxamida úteis para o tratamento de doenças favorecidas por insuficiente hidratação das mucosas
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1672029A (en) * 1924-08-05 1928-06-05 C A F Kahlbaum Chem Fab G M B Process for the production of amidoguanidines and their alkyl derivatives
US2408694A (en) * 1942-05-29 1946-10-01 Libbey Owens Ford Glass Co Method of preparing acyl guanidines

Also Published As

Publication number Publication date
US3300494A (en) 1967-01-24
CH471798A (de) 1969-04-30
GB1067473A (en) 1967-05-03
GB1067474A (en) 1967-05-03
DK108310C (da) 1967-11-13
DE1470052A1 (de) 1969-02-13
DK108864C (da) 1968-02-19
BR6353917D0 (pt) 1973-07-12
BE639393A (pt)
SE348734B (pt) 1972-09-11
CH454879A (de) 1968-04-30
SE319179B (pt) 1970-01-12
FR1552762A (pt) 1969-01-10
SE334614B (pt) 1971-05-03
MY7000080A (en) 1970-12-31
NL299929A (pt)

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