CY1120861T1 - Συνθεσεις και μεθοδοι για θεραπευτικη αγωγη διαβητη τυπου 1 - Google Patents
Συνθεσεις και μεθοδοι για θεραπευτικη αγωγη διαβητη τυπου 1Info
- Publication number
- CY1120861T1 CY1120861T1 CY181100931T CY181100931T CY1120861T1 CY 1120861 T1 CY1120861 T1 CY 1120861T1 CY 181100931 T CY181100931 T CY 181100931T CY 181100931 T CY181100931 T CY 181100931T CY 1120861 T1 CY1120861 T1 CY 1120861T1
- Authority
- CY
- Cyprus
- Prior art keywords
- methods
- compositions
- treatment
- diabetes type
- administering
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/577—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 tolerising response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/101—Plasmid DNA for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/106—Plasmid DNA for vertebrates
- C12N2800/107—Plasmid DNA for vertebrates for mammalian
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/24—Vectors characterised by the absence of particular element, e.g. selectable marker, viral origin of replication
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Η παρούσα εφεύρεση παρέχει συνθέσεις και μεθόδους για θεραπευτική αγωγή ινσουλινοεξαρτώμενου σακχαρώδη διαβήτη σε υποκείμενο που περιλαμβάνει χορήγηση αυτοφορέα που κωδικοποιεί και εκφράζει ανθρώπινη προϊνσουλίνη.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361818671P | 2013-05-02 | 2013-05-02 | |
PCT/US2014/036394 WO2014179586A1 (en) | 2013-05-02 | 2014-05-01 | Compositions and methods for treatment of type 1 diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1120861T1 true CY1120861T1 (el) | 2019-12-11 |
Family
ID=51843952
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY181100931T CY1120861T1 (el) | 2013-05-02 | 2018-09-06 | Συνθεσεις και μεθοδοι για θεραπευτικη αγωγη διαβητη τυπου 1 |
Country Status (14)
Country | Link |
---|---|
US (2) | US20160068585A1 (el) |
EP (1) | EP2992094B1 (el) |
JP (2) | JP2016518844A (el) |
CN (1) | CN105408478A (el) |
CY (1) | CY1120861T1 (el) |
DK (1) | DK2992094T3 (el) |
ES (1) | ES2687189T3 (el) |
HR (1) | HRP20181445T1 (el) |
HU (1) | HUE040421T2 (el) |
LT (1) | LT2992094T (el) |
PL (1) | PL2992094T3 (el) |
PT (1) | PT2992094T (el) |
SI (1) | SI2992094T1 (el) |
WO (1) | WO2014179586A1 (el) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20230364261A1 (en) * | 2020-09-21 | 2023-11-16 | Sri International | Targeted antigen delivery system and uses thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002045735A2 (en) * | 2000-12-08 | 2002-06-13 | University Technologies International, Inc. | Nrp-derived peptides useful for treating insulin-dependent diabetes mellitus |
WO2010080976A1 (en) * | 2009-01-09 | 2010-07-15 | Sdg, Inc. (An Ohio Corporation) | Insulin therapies for the treatment of diabetes, diabetes related ailments, and/or diseases or conditions other than diabetes or diabetes related ailments |
US20180092991A1 (en) * | 2009-06-05 | 2018-04-05 | Bayhill Therapeutics, Inc. | Compositions and methods for treatment of insulin-dependent diabetes mellitus |
WO2012015903A1 (en) * | 2010-07-27 | 2012-02-02 | Bayhill Therapeutics, Inc. | Treatment of type i diabetes mellitus (t1dm) in young newly diagnosed patients |
-
2014
- 2014-05-01 PL PL14791797T patent/PL2992094T3/pl unknown
- 2014-05-01 JP JP2016512043A patent/JP2016518844A/ja not_active Withdrawn
- 2014-05-01 SI SI201430885T patent/SI2992094T1/sl unknown
- 2014-05-01 DK DK14791797.5T patent/DK2992094T3/en active
- 2014-05-01 PT PT14791797T patent/PT2992094T/pt unknown
- 2014-05-01 WO PCT/US2014/036394 patent/WO2014179586A1/en active Application Filing
- 2014-05-01 HU HUE14791797A patent/HUE040421T2/hu unknown
- 2014-05-01 US US14/888,639 patent/US20160068585A1/en not_active Abandoned
- 2014-05-01 EP EP14791797.5A patent/EP2992094B1/en active Active
- 2014-05-01 LT LTEP14791797.5T patent/LT2992094T/lt unknown
- 2014-05-01 ES ES14791797.5T patent/ES2687189T3/es active Active
- 2014-05-01 CN CN201480038111.XA patent/CN105408478A/zh active Pending
-
2018
- 2018-09-06 CY CY181100931T patent/CY1120861T1/el unknown
- 2018-09-10 HR HRP20181445TT patent/HRP20181445T1/hr unknown
- 2018-11-21 US US16/197,578 patent/US20190315827A1/en not_active Abandoned
-
2019
- 2019-02-04 JP JP2019017697A patent/JP2019080574A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2016518844A (ja) | 2016-06-30 |
PT2992094T (pt) | 2018-10-18 |
CN105408478A (zh) | 2016-03-16 |
DK2992094T3 (en) | 2018-09-03 |
EP2992094B1 (en) | 2018-06-20 |
JP2019080574A (ja) | 2019-05-30 |
EP2992094A4 (en) | 2016-12-28 |
LT2992094T (lt) | 2018-11-12 |
PL2992094T3 (pl) | 2019-03-29 |
HRP20181445T1 (hr) | 2018-11-16 |
SI2992094T1 (sl) | 2018-12-31 |
US20160068585A1 (en) | 2016-03-10 |
ES2687189T3 (es) | 2018-10-24 |
EP2992094A1 (en) | 2016-03-09 |
US20190315827A1 (en) | 2019-10-17 |
WO2014179586A1 (en) | 2014-11-06 |
HUE040421T2 (hu) | 2019-03-28 |
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