CY1117196T1 - Heterocyclic compounds and their uses - Google Patents
Heterocyclic compounds and their usesInfo
- Publication number
- CY1117196T1 CY1117196T1 CY20161100119T CY161100119T CY1117196T1 CY 1117196 T1 CY1117196 T1 CY 1117196T1 CY 20161100119 T CY20161100119 T CY 20161100119T CY 161100119 T CY161100119 T CY 161100119T CY 1117196 T1 CY1117196 T1 CY 1117196T1
- Authority
- CY
- Cyprus
- Prior art keywords
- inflammatory
- cell
- limited
- bowel disorders
- diseases
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Υποκατεστημένα δικυκλικά ετεροαρύλια και συνθέσεις που περιέχουν αυτά, για τη θεραπεία γενικής φλεγμονής, αρθρίτιδας, ρευματικών ασθενειών, οστεοαρθρίτιδας, διαταραχών φλεγμονώδους εντέρου, φλεγμονωδών διαταραχών οφθαλμού, φλεγμονωδών ή ασταθών διαταραχών κύστης, ψωρίασης, παθήσεων του δέρματος με φλεγμονώδη συστατικά, χρόνιων φλεγμονωδών καταστάσεων, που συμπεριλαμβάνουν, αλλά δεν περιορίζεται σε αυτές, αυτοάνοσες ασθένειες όπως ερυθηματώδη συστημικό λύκο (SLE), προϊούσα μυασθένεια, ρευματοειδή αρθρίτιδα, οξεία διάχυτο εγκεφαλομυελίτιδα, ιδιοπαθή θρομβοκυτοπενική πορφύρα, σκλήρυνση κατά πλάκας, σύνδρομο Sjogren και αυτοάνοση αιμολυτική αναιμία, αλλεργικών καταστάσεων που συμπεριλαμβάνουν όλες τις μορφές υπερευαισθησίας. Η παρούσα εφεύρεση επίσης επιτρέπει μεθόδους θεραπείας καρκίνων που προκαλούνται, εξαρτώνται ή συνδυάζονται με δραστικότητα ρ110, που συμπεριλαμβάνουν αλλά δεν περιορίζονται σε αυτές, λευχαιμίες, όπως οξεία μυελοειδή λευχαιμία (AML), μυελο-δυσπλαστικό σύνδρομο (MDS), μυελο-πολλαπλασιαστικές ασθένειες (MPD), χρόνια μυελοειδή λευχαιμία(CML), Τ-κυττάρου οξεία λεμφοβλαστική λευχαιμία (T-ALL), Β-κυττάρου οξεία λεμφοβλαστική λευχαιμία (B-ALL), λέμφωμα μη Hodgkins (NHL), Β-κυττάρου λέμφωμα και συμπαγείς όγκους, όπως καρκίνο μαστού.Substituted bicyclic heteroaryls and compositions containing them for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory bowel disorders, inflammatory or inflammatory diseases include, but are not limited to, autoimmune diseases such as systemic lupus erythematosus, progressive myasthenia, rheumatoid arthritis, acute diffuse encephalomyelitis na, idiopathic thrombocytopenic purpura, multiple sclerosis, Sjogren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity. The present invention also allows for methods of treating cancers that are induced, dependent or associated with p110 activity, including, but not limited to, leukemias, such as acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), myelodysplastic MP (MD). ), chronic myeloid leukemia (CML), T-cell acute lymphoblastic leukemia (T-ALL), B-cell acute lymphoblastic leukemia (B-ALL), non-Hodgkins lymphoma (NHL), B-cell lymphoma and solid tumors, such as carcinomas breast.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91956807A | 2007-03-23 | 2007-03-23 | |
| EP08727163.1A EP2137186B1 (en) | 2007-03-23 | 2008-03-24 | Heterocyclic compounds and their uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1117196T1 true CY1117196T1 (en) | 2017-04-05 |
Family
ID=58487084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20161100119T CY1117196T1 (en) | 2007-03-23 | 2016-02-15 | Heterocyclic compounds and their uses |
Country Status (1)
| Country | Link |
|---|---|
| CY (1) | CY1117196T1 (en) |
-
2016
- 2016-02-15 CY CY20161100119T patent/CY1117196T1/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA201270013A1 (en) | HETEROCYCLIC COMPOUNDS AND THEIR APPLICATION | |
| MX2009009968A (en) | Heterocyclic compounds and their uses. | |
| MY184620A (en) | Heterocyclic compounds and their uses | |
| MX2012015134A (en) | Heterocyclic compounds and their use as inhibitors of pi3k activity. | |
| CY1117487T1 (en) | Heterocyclic compounds and their uses | |
| MX2013007261A (en) | Heterocyclic compounds and their uses. | |
| MX2011013666A (en) | Heterocyclic compounds and their uses. | |
| MX2009009913A (en) | Derivatives of quinoline or benzopyrazine and their uses for the treatment of (inter alia) inflammatory diseases, autoimmune diseases or various kinds of cancer. | |
| MX2011013667A (en) | Heterocyclic compounds and their uses as inhibitors of pi3 k activity. | |
| MX2012015135A (en) | Heterocyclic compounds and their use as inhibitors of pi3k activity. | |
| MX2012015143A (en) | Nitrogen containing heterocyclic compounds as pik3 -delta inhibitors. | |
| MX2009010050A (en) | δ3- substituted quinoline or quinoxaline derivatives and their use as phosphatidylinositol 3-kinase ( pi3k) inhibitors. | |
| MX2011013901A (en) | 4h - pyrido [ 1, 2 - a] pyrimidin - 4 - one derivatives as pi3 k inhibitors. | |
| MX2012015147A (en) | Heterocyclic compounds and their use as inhibitors of pi3k activity. | |
| JP2018531215A5 (en) | ||
| PH12019502138A1 (en) | Compounds and compositions for treating hematological disorders | |
| RU2018107668A (en) | Pyrazolpyrimidine derivative and its use | |
| SG11202008696RA (en) | Use of caloric restriction mimetics for potentiating chemo-immunotherapy for the treatment of cancers | |
| TR201909997T4 (en) | Amide compounds as 5-HT4 receptor agonists. | |
| CY1117196T1 (en) | Heterocyclic compounds and their uses | |
| CY1114775T1 (en) | 3-Substituted Quinoline or Quinoxaline Derivative and Their Use as Phosphatidylinositol 3-Kinase Inhibitors (R3K) | |
| AR090705A1 (en) | PIRIDINE AND PYRIMIDINE COMPOUNDS AND THEIR USES AS 3-QUINASE PHOSPHYTIDYLINOSITOL INHIBITORS (PI3K) | |
| UA100699C2 (en) | Antibody to human cd20 and using thereof for the treatment cd20-mediated disease or condition |