CY1116795T1 - CODES AND RELATED Molecules Binding to Protein TOY PSCA - Google Patents
CODES AND RELATED Molecules Binding to Protein TOY PSCAInfo
- Publication number
- CY1116795T1 CY1116795T1 CY20151100913T CY151100913T CY1116795T1 CY 1116795 T1 CY1116795 T1 CY 1116795T1 CY 20151100913 T CY20151100913 T CY 20151100913T CY 151100913 T CY151100913 T CY 151100913T CY 1116795 T1 CY1116795 T1 CY 1116795T1
- Authority
- CY
- Cyprus
- Prior art keywords
- psca
- protein
- toy
- codes
- related molecules
- Prior art date
Links
Abstract
Αντισώματα και μόρια που προέρχονται από αυτά που δεσμεύονται σε καινοφανή πρωτεΐνη του PSCA και παραλλάγματα εξ αυτών περιγράφονται όπου το PSCA εκδηλώνει συγκεκριμένη για ιστούς έκφραση σε φυσιολογικό ιστό ενηλίκων, και εκφράζεται κατά παρεκκλίνοντα τρόπο στους καρκίνους που καταλογογραφούνται στον Πίνακα I. Επακόλουθα, το PSCA παρέχει διαγνωστικό, προγνωστικό, προφυλακτικό και/ή θεραπευτικό στόχο για καρκίνο. Το γονίδιο του PSCA ή το θραύσμα εξ αυτού, ή η εγκωδικευθείσα πρωτεΐνη αυτού, ή τα παραλλάγματα εξ αυτής, ή ένα θραύσμα εξ αυτής, μπορούν να χρησιμοποιηθούν για να εκμαιευθεί χυμική ή κυτταρική ανοσιακή απόκριση• αντισώματα ή κύτταρα Τ δραστικά με το PSCA μπορούν να χρησιμοποιηθούν σε ενεργητική ή παθητική ανοσοποίηση.Antibodies and molecules derived from those that bind to a novel PSCA protein and variants thereof are described where the PSCA expresses tissue-specific expression in normal adult tissue, and is expressed in derogation to the cancers listed in Table I. diagnostic, prognostic, prophylactic and / or therapeutic target for cancer. The PSCA gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, may be used to elicit a humoral or cellular immune response; antibodies or T cells active with PSCA may used in active or passive immunization.
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/857,484 US7622564B2 (en) | 2003-05-30 | 2004-05-28 | Prostate stem cell antigen (PSCA) variants and subsequences thereof |
| US61638104A | 2004-10-05 | 2004-10-05 | |
| US61788104A | 2004-10-12 | 2004-10-12 | |
| US62131004A | 2004-10-21 | 2004-10-21 | |
| US63307704A | 2004-12-02 | 2004-12-02 | |
| US67200005A | 2005-04-14 | 2005-04-14 | |
| EP05752076.9A EP1753871B1 (en) | 2004-05-28 | 2005-05-17 | Antibodies and related molecules that bind to psca proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1116795T1 true CY1116795T1 (en) | 2017-03-15 |
Family
ID=58459739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20151100913T CY1116795T1 (en) | 2004-05-28 | 2015-10-09 | CODES AND RELATED Molecules Binding to Protein TOY PSCA |
Country Status (1)
| Country | Link |
|---|---|
| CY (1) | CY1116795T1 (en) |
-
2015
- 2015-10-09 CY CY20151100913T patent/CY1116795T1/en unknown
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