CY1114183T1 - Κοκκωδης ουσια για τον σχηματισμο δισκιων διασπειρομενων στο στομα - Google Patents
Κοκκωδης ουσια για τον σχηματισμο δισκιων διασπειρομενων στο στομαInfo
- Publication number
- CY1114183T1 CY1114183T1 CY20131100657T CY131100657T CY1114183T1 CY 1114183 T1 CY1114183 T1 CY 1114183T1 CY 20131100657 T CY20131100657 T CY 20131100657T CY 131100657 T CY131100657 T CY 131100657T CY 1114183 T1 CY1114183 T1 CY 1114183T1
- Authority
- CY
- Cyprus
- Prior art keywords
- mouth
- granular substances
- granulate
- forming dispersants
- dispersants
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/16—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by suspending the powder material in a gas, e.g. in fluidised beds or as a falling curtain
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biochemistry (AREA)
- Nutrition Science (AREA)
- Neurology (AREA)
- Otolaryngology (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Η παρούσα εφεύρεση αφορά μια κοκκώδη ουσία που περιέχει μαννιτόλη και σορβιτόλη σε μια αναλογία βάρους μεταξύ 70:30 και 97:3. Η εφεύρεση αφορά επίσης τη χρήση της εν λόγω κοκκώδους ουσίας στην παρασκευή διασπειρόμενων στο στόμα δισκίων, τα διασπειρόμενα στο στόμα δισκία που λαμβάνεται με την εν λόγω κοκκώδη ουσία και μια διαδικασία παραγωγής για τη λήψη της εν λόγω κοκκώδους ουσίας.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09425135.2A EP2238974B9 (en) | 2009-04-09 | 2009-04-09 | Granulate for the formulation of orodispersible tablets |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1114183T1 true CY1114183T1 (el) | 2016-08-31 |
Family
ID=40909993
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20131100657T CY1114183T1 (el) | 2009-04-09 | 2013-08-01 | Κοκκωδης ουσια για τον σχηματισμο δισκιων διασπειρομενων στο στομα |
Country Status (10)
Country | Link |
---|---|
US (3) | US20100260854A1 (el) |
EP (1) | EP2238974B9 (el) |
CA (1) | CA2697576C (el) |
CY (1) | CY1114183T1 (el) |
DK (1) | DK2238974T3 (el) |
ES (1) | ES2422281T3 (el) |
HR (1) | HRP20130805T2 (el) |
PL (1) | PL2238974T3 (el) |
PT (1) | PT2238974E (el) |
SI (1) | SI2238974T1 (el) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2422281T3 (es) * | 2009-04-09 | 2013-09-10 | E Pharma Trento Spa | Granulado para la formulación de comprimidos bucodispersables |
EP3288556A4 (en) | 2015-04-29 | 2018-09-19 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5622719A (en) | 1993-09-10 | 1997-04-22 | Fuisz Technologies Ltd. | Process and apparatus for making rapidly dissolving dosage units and product therefrom |
US5576014A (en) * | 1994-01-31 | 1996-11-19 | Yamanouchi Pharmaceutical Co., Ltd | Intrabuccally dissolving compressed moldings and production process thereof |
DE19615418A1 (de) * | 1996-04-22 | 1997-10-23 | Merck Patent Gmbh | Polyol-Zusammensetzung |
JP4947833B2 (ja) | 1997-07-25 | 2012-06-06 | アルペックス・ファルマ・ソシエテ・アノニム | 速崩壊性口内溶解錠の製造に適した顆粒の製造方法 |
FR2785538B1 (fr) | 1998-11-06 | 2004-04-09 | Prographarm Laboratoires | Comprime a delitement rapide perfectionne |
FR2787110B1 (fr) * | 1998-12-11 | 2001-02-16 | Roquette Freres | Sorbitol pulverulent et son procede de preparation |
NZ512166A (en) * | 2001-06-01 | 2003-09-26 | Marketing Brokers Nz Ltd | Wax applicator with a cylindrical roller having convex ends. |
ATE346590T1 (de) | 2001-07-26 | 2006-12-15 | Ethypharm Sa | Umgehüllte allylamine oder benzylamine enthaltende granulate, verfahren zur herstellung und in der mundhöhle dispergierbare tabletten enthaltend die umgehüllten granulate |
US7118765B2 (en) * | 2001-12-17 | 2006-10-10 | Spi Pharma, Inc. | Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms |
FI20021312A (fi) * | 2002-07-03 | 2004-01-04 | Danisco Sweeteners Oy | Polyolikoostumusten kiteyttäminen, kiteinen polyolikoostumustuote ja sen käyttö |
AU2005271036B2 (en) * | 2004-08-12 | 2009-11-19 | Reckitt Benckiser Healthcare (Uk) Limited | Granules comprising paracetamol a NSAID and a sugar alcohol made by melt extrusion |
FR2894475B1 (fr) | 2005-12-14 | 2008-05-16 | Servier Lab | Composition pharmaceutique orodispersible pour administra- -tion oromucosale ou sublinguale d'agomelatine |
US20070212417A1 (en) * | 2006-03-07 | 2007-09-13 | Cherukuri S R | Compressible resilient granules and formulations prepared therefrom |
FR2898492B1 (fr) | 2006-03-15 | 2008-06-06 | Pierre Fabre Medicament Sa | Comprimes orodispersibles de domperidone |
CN102046147B (zh) * | 2007-06-06 | 2013-03-20 | 巴斯夫欧洲公司 | 用于制备快速崩解的片剂的药物配制剂 |
ES2422281T3 (es) * | 2009-04-09 | 2013-09-10 | E Pharma Trento Spa | Granulado para la formulación de comprimidos bucodispersables |
-
2009
- 2009-04-09 ES ES09425135T patent/ES2422281T3/es active Active
- 2009-04-09 EP EP09425135.2A patent/EP2238974B9/en active Active
- 2009-04-09 PT PT94251352T patent/PT2238974E/pt unknown
- 2009-04-09 DK DK09425135.2T patent/DK2238974T3/da active
- 2009-04-09 PL PL09425135T patent/PL2238974T3/pl unknown
- 2009-04-09 SI SI200930670T patent/SI2238974T1/sl unknown
-
2010
- 2010-03-23 CA CA2697576A patent/CA2697576C/en not_active Expired - Fee Related
- 2010-04-02 US US12/753,571 patent/US20100260854A1/en not_active Abandoned
-
2013
- 2013-08-01 CY CY20131100657T patent/CY1114183T1/el unknown
- 2013-08-26 HR HRP20130805AT patent/HRP20130805T2/hr unknown
-
2015
- 2015-08-18 US US14/828,692 patent/US9861581B2/en active Active
-
2017
- 2017-12-04 US US15/830,044 patent/US10632073B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CA2697576A1 (en) | 2010-10-09 |
CA2697576C (en) | 2017-07-11 |
EP2238974B9 (en) | 2014-05-21 |
HRP20130805T2 (en) | 2013-10-11 |
US9861581B2 (en) | 2018-01-09 |
US20180092849A1 (en) | 2018-04-05 |
US20160045438A1 (en) | 2016-02-18 |
PT2238974E (pt) | 2013-07-09 |
ES2422281T3 (es) | 2013-09-10 |
US10632073B2 (en) | 2020-04-28 |
EP2238974B1 (en) | 2013-06-05 |
HRP20130805T1 (en) | 2013-09-30 |
DK2238974T3 (da) | 2013-08-26 |
PL2238974T3 (pl) | 2013-09-30 |
US20100260854A1 (en) | 2010-10-14 |
EP2238974A1 (en) | 2010-10-13 |
SI2238974T1 (sl) | 2013-09-30 |
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