CY1114107T1 - COMPOSITIONS AND METHODS FOR DETERMINING SPECIFIC NUCLEAR NUCLEAR ACIDS IN URINE - Google Patents

COMPOSITIONS AND METHODS FOR DETERMINING SPECIFIC NUCLEAR NUCLEAR ACIDS IN URINE

Info

Publication number
CY1114107T1
CY1114107T1 CY20131100547T CY131100547T CY1114107T1 CY 1114107 T1 CY1114107 T1 CY 1114107T1 CY 20131100547 T CY20131100547 T CY 20131100547T CY 131100547 T CY131100547 T CY 131100547T CY 1114107 T1 CY1114107 T1 CY 1114107T1
Authority
CY
Cyprus
Prior art keywords
methods
nuclear
viruses
urine
viral
Prior art date
Application number
CY20131100547T
Other languages
Greek (el)
Inventor
Hovsep Melkonyan
Angela Cannas
Louis David Tomei
Samuil R Umansky
Original Assignee
Trovagene, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/137,935 external-priority patent/US7973154B2/en
Priority claimed from EP06748221A external-priority patent/EP1856295B1/en
Application filed by Trovagene, Inc. filed Critical Trovagene, Inc.
Publication of CY1114107T1 publication Critical patent/CY1114107T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Η παρούσα εφεύρεση σχετίζεται με μεθόδους για την διάγνωση ή επιτήρηση ιικής λοίμωξης ανιχνεύοντας την παρουσία διανεφρικών ιικών πυρηνικών οξέων ή πυρηνικών οξέων ιικής προέλευσης σε δείγμα ούρων, με ή χωρίς απομόνωση των πυρηνικών οξέων από δείγμα ούρων. Η ανάλυση των πυρηνικών οξέων πραγματοποιείται μέσω υβριδοποίησης των πυρηνικών οξέων με ειδικούς ιχνηθέτες, ή μέσω αντίδρασης ενίσχυσης αλύσων με ειδικούς εκκινητές. Οι μέθοδοι είναι εφαρμόσιμες σε όλους τους ιικούς παθογόνους παράγοντες, που συμπεριλαμβάνουν ιούς RΝΑ, DΝΑ, επισωματικούς, ή ενσωματωμένους ιούς.The present invention relates to methods for the diagnosis or surveillance of viral infection by detecting the presence of transgenic viral nucleic acids or nucleic acids of viral origin in a urine sample, with or without isolation of uric acid from the urine sample. Nucleic acid analysis is performed by hybridizing the nucleic acids with specific probes, or by chain reaction amplification with specific primers. The methods are applicable to all viral pathogens, including RNA viruses, DNA viruses, somatic viruses, or embedded viruses.

CY20131100547T 2005-02-17 2013-07-03 COMPOSITIONS AND METHODS FOR DETERMINING SPECIFIC NUCLEAR NUCLEAR ACIDS IN URINE CY1114107T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT000068A ITRM20050068A1 (en) 2005-02-17 2005-02-17 METHOD FOR THE DETECTION OF NUCLEIC ACIDS OF BACTERIAL OR PATENT PATOGEN AGENTS IN URINE.
US11/137,935 US7973154B2 (en) 2005-02-17 2005-05-25 Kits for diagnosis and monitoring of viral infection by analysis of viral transrenal nucleic acids in urine
EP06748221A EP1856295B1 (en) 2005-02-17 2006-02-16 Compositions and methods for detecting viral specific nucleic acids in urine

Publications (1)

Publication Number Publication Date
CY1114107T1 true CY1114107T1 (en) 2016-07-27

Family

ID=36763294

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20131100547T CY1114107T1 (en) 2005-02-17 2013-07-03 COMPOSITIONS AND METHODS FOR DETERMINING SPECIFIC NUCLEAR NUCLEAR ACIDS IN URINE

Country Status (10)

Country Link
US (1) US7803929B2 (en)
JP (2) JP5281293B2 (en)
CN (2) CN103045758A (en)
CY (1) CY1114107T1 (en)
DK (1) DK1856295T3 (en)
ES (1) ES2410598T3 (en)
HK (1) HK1110903A1 (en)
IT (1) ITRM20050068A1 (en)
PT (1) PT1856295E (en)
SI (1) SI1856295T1 (en)

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Also Published As

Publication number Publication date
ITRM20050068A1 (en) 2006-08-18
CN101253273B (en) 2013-08-28
DK1856295T3 (en) 2013-07-01
CN101253273A (en) 2008-08-27
JP2008536481A (en) 2008-09-11
US20060183107A1 (en) 2006-08-17
HK1110903A1 (en) 2008-07-25
PT1856295E (en) 2013-07-10
ES2410598T3 (en) 2013-07-02
US7803929B2 (en) 2010-09-28
JP5281293B2 (en) 2013-09-04
JP2013143946A (en) 2013-07-25
SI1856295T1 (en) 2013-08-30
CN103045758A (en) 2013-04-17

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