CY1107455T1 - Συνθεση και μεθοδος για την προκληση αποπτωσης σε καρκινικα κυτταρα του προστατη - Google Patents

Συνθεση και μεθοδος για την προκληση αποπτωσης σε καρκινικα κυτταρα του προστατη

Info

Publication number
CY1107455T1
CY1107455T1 CY20051100946T CY051100946T CY1107455T1 CY 1107455 T1 CY1107455 T1 CY 1107455T1 CY 20051100946 T CY20051100946 T CY 20051100946T CY 051100946 T CY051100946 T CY 051100946T CY 1107455 T1 CY1107455 T1 CY 1107455T1
Authority
CY
Cyprus
Prior art keywords
protection
composition
cancer cells
animal
dna
Prior art date
Application number
CY20051100946T
Other languages
English (en)
Inventor
Nigel C Phillips
Mario C Filion
Stéphanie READER
Original Assignee
Bioniche Life Sciences Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioniche Life Sciences Inc. filed Critical Bioniche Life Sciences Inc.
Publication of CY1107455T1 publication Critical patent/CY1107455T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/711Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5063Compounds of unknown constitution, e.g. material from plants or animals
    • A61K9/5068Cell membranes or bacterial membranes enclosing drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Μέθοδος για τη θεραπεία του καρκίνου του προστάτη σε ένα πειραματόζωο, όπου χορηγείται στο πειραματόζωο που χρειάζεται μια τέτοια θεραπεία μια σύνθεση που περιέχει DNA Mycobacterium phlei (Μ. phlei) (M-DNA) και M-DNA διατηρούμενο και συμπλοκοποιημένο επί του κυτταρικού τοιχώματος Μ. phlei (MCC) σε ποσότητα αποτελεσματική για να έχουμε αντινεοπλασματικό αποτέλεσμα επί των καρκινικών κυττάρων στον προστάτη του πειραματoζώου.
CY20051100946T 1999-04-01 2005-08-03 Συνθεση και μεθοδος για την προκληση αποπτωσης σε καρκινικα κυτταρα του προστατη CY1107455T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12745199P 1999-04-01 1999-04-01
EP00912310A EP1165106B8 (en) 1999-04-01 2000-03-30 Composition and method for inducing apoptosis in prostate cancer cells by m-dna and mcc

Publications (1)

Publication Number Publication Date
CY1107455T1 true CY1107455T1 (el) 2012-12-19

Family

ID=22430191

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20051100946T CY1107455T1 (el) 1999-04-01 2005-08-03 Συνθεση και μεθοδος για την προκληση αποπτωσης σε καρκινικα κυτταρα του προστατη

Country Status (10)

Country Link
EP (1) EP1165106B8 (el)
JP (1) JP2002541114A (el)
AT (1) ATE296106T1 (el)
AU (1) AU780909B2 (el)
CA (1) CA2366090C (el)
CY (1) CY1107455T1 (el)
DE (1) DE60020352T2 (el)
ES (1) ES2238996T3 (el)
PT (1) PT1165106E (el)
WO (1) WO2000059518A2 (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000033879A1 (en) * 1998-12-04 2000-06-15 Bioniche Life Sciences Inc. Method for the treatment of inflammation
US20030044352A1 (en) * 2001-04-24 2003-03-06 Phillips Nigel C. Method for evaluating the efficacy of treatment with bacterial DNA and bacterial cell walls

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU736450B2 (en) * 1997-08-05 2001-07-26 Bioniche Urology Ip Inc. Composition and method for regulating cell proliferation and cell death

Also Published As

Publication number Publication date
EP1165106B8 (en) 2005-07-27
JP2002541114A (ja) 2002-12-03
EP1165106A2 (en) 2002-01-02
WO2000059518A2 (en) 2000-10-12
DE60020352T2 (de) 2005-10-20
AU3413500A (en) 2000-10-23
DE60020352D1 (de) 2005-06-30
AU780909B2 (en) 2005-04-21
EP1165106B1 (en) 2005-05-25
ES2238996T3 (es) 2005-09-16
CA2366090A1 (en) 2000-10-12
PT1165106E (pt) 2005-10-31
ATE296106T1 (de) 2005-06-15
CA2366090C (en) 2011-05-24
WO2000059518A3 (en) 2001-02-01

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