CY1106435T1 - Αλφα λιπονικο οξυ σε κρυσταλλινη μορφη - Google Patents
Αλφα λιπονικο οξυ σε κρυσταλλινη μορφηInfo
- Publication number
- CY1106435T1 CY1106435T1 CY20021100024T CY021100024T CY1106435T1 CY 1106435 T1 CY1106435 T1 CY 1106435T1 CY 20021100024 T CY20021100024 T CY 20021100024T CY 021100024 T CY021100024 T CY 021100024T CY 1106435 T1 CY1106435 T1 CY 1106435T1
- Authority
- CY
- Cyprus
- Prior art keywords
- fatty acid
- crystalline form
- enantiomer
- alpha
- alpha fatty
- Prior art date
Links
- 235000014113 dietary fatty acids Nutrition 0.000 title 1
- 229930195729 fatty acid Natural products 0.000 title 1
- 239000000194 fatty acid Substances 0.000 title 1
- 150000004665 fatty acids Chemical class 0.000 title 1
- AGBQKNBQESQNJD-SSDOTTSWSA-N (R)-lipoic acid Chemical compound OC(=O)CCCC[C@@H]1CCSS1 AGBQKNBQESQNJD-SSDOTTSWSA-N 0.000 abstract 1
- AGBQKNBQESQNJD-UHFFFAOYSA-N alpha-Lipoic acid Natural products OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 abstract 1
- 235000019136 lipoic acid Nutrition 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 238000000634 powder X-ray diffraction Methods 0.000 abstract 1
- 229960002663 thioctic acid Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Seasonings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19810336A DE19810336A1 (de) | 1998-03-11 | 1998-03-11 | Alpha-Liponsäure mit neuartiger Modifikation |
| US09/074,645 US5994393A (en) | 1998-03-11 | 1998-05-08 | Alpha-lipoic acid with novel modification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1106435T1 true CY1106435T1 (el) | 2011-04-06 |
Family
ID=26044524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20021100024T CY1106435T1 (el) | 1998-03-11 | 2002-01-30 | Αλφα λιπονικο οξυ σε κρυσταλλινη μορφη |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5994393A (enExample) |
| EP (1) | EP0949258B1 (enExample) |
| AT (1) | ATE207914T1 (enExample) |
| CA (1) | CA2265276C (enExample) |
| CY (1) | CY1106435T1 (enExample) |
| DE (2) | DE19810336A1 (enExample) |
| DK (1) | DK0949258T3 (enExample) |
| ES (1) | ES2164474T3 (enExample) |
| IN (1) | IN186598B (enExample) |
| PT (1) | PT949258E (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19834608A1 (de) * | 1998-07-31 | 2000-02-03 | Basf Ag | Kristallmodifikation der Liponsäure |
| AU2001270554A1 (en) * | 2000-06-06 | 2001-12-17 | Basf Aktiengesellschaft | Use of an (r)-enantiomer of lipoic acid in cosmetics and dermatologicals |
| DE10151764A1 (de) * | 2001-10-19 | 2003-05-08 | Basf Ag | Kombination von Liponsäure und Glutamin in Lebens- und Arzneimitteln |
| WO2006058278A2 (en) * | 2004-11-24 | 2006-06-01 | Hill's Pet Nutrition, Inc. | Methods for improving liver clearance of xenobiotic substances in an animal |
| US20090176864A1 (en) * | 2004-11-24 | 2009-07-09 | Hill's Pet Nutrition, Inc. | Methods For Improving Hepatic and Immune Function In An Animal |
| BRPI0519610A2 (pt) | 2004-12-30 | 2009-02-25 | Hills Pet Nutrition Inc | mÉtodos para melhorar a qualidade de vida de um animal idoso ou muito idoso, de um canino de raÇa regular ou pequena, idoso ou muito idoso, de um cço de raÇa grande idoso ou muito idoso, e de um gato idoso ou muito idoso |
| US8252742B2 (en) | 2004-12-30 | 2012-08-28 | Hill's Pet Nutrition, Inc. | Methods for enhancing the quality of life of a senior animal |
| EP2389178A4 (en) * | 2008-12-01 | 2012-06-06 | Invasc Therapeutic Inc | COMPOSITIONS CONTAINING INHIBITORS OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM AND LIPOIC ACID COMPOUNDS, AND THEIR USE FOR THE TREATMENT OF RENIN-ANGIOTENSIN-ALDOSTERONE ASSOCIATED DISORDERS |
| CN108484570B (zh) * | 2018-05-15 | 2021-05-04 | 苏州富士莱医药股份有限公司 | 一种制备硫辛酸颗粒的方法及设备 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0427247T3 (da) * | 1989-11-09 | 1998-09-28 | Asta Medica Ag | Lægemiddel indeholdende R-alpha- lipoinsyre eller S-alphalipoinsyre som aktiv bestanddel |
| DE4218572A1 (de) * | 1992-06-05 | 1993-12-09 | Asta Medica Ag | Synergistische Kombination von Arzneimitteln enthaltend als Wirkstoff alpha-Liponsäure, Dihydroliponsäure, deren Metaboliten sowie die oxidierten und reduzierten Enantiomere der alpha-Liponsäure wie die R-alpha-Liponsäure oder S-alpha-Liponsäure sowie Metaboliten der alpha-Liponsäure mit den Vitaminen A, B1-6, B12, C und E |
| DE4235912C2 (de) * | 1992-10-23 | 2002-12-05 | Viatris Gmbh | Verfahren zur Herstellung kristalliner Thioctsäure und deren Verwendung |
| DE4433764A1 (de) * | 1994-09-22 | 1996-03-28 | Asta Medica Ag | Darreichungsformen enthaltend alpha-Liponsäure, feste Salze von R-Thioctsäure mit verbesserter Freisetzung und Bioverfügbarkeit |
-
1998
- 1998-03-11 DE DE19810336A patent/DE19810336A1/de not_active Withdrawn
- 1998-05-08 US US09/074,645 patent/US5994393A/en not_active Expired - Lifetime
-
1999
- 1999-03-02 ES ES99104155T patent/ES2164474T3/es not_active Expired - Lifetime
- 1999-03-02 AT AT99104155T patent/ATE207914T1/de active
- 1999-03-02 DE DE59900364T patent/DE59900364D1/de not_active Expired - Lifetime
- 1999-03-02 PT PT99104155T patent/PT949258E/pt unknown
- 1999-03-02 EP EP99104155A patent/EP0949258B1/de not_active Expired - Lifetime
- 1999-03-02 DK DK99104155T patent/DK0949258T3/da active
- 1999-03-11 CA CA002265276A patent/CA2265276C/en not_active Expired - Fee Related
- 1999-04-06 IN IN317CA1999 patent/IN186598B/en unknown
-
2002
- 2002-01-30 CY CY20021100024T patent/CY1106435T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE207914T1 (de) | 2001-11-15 |
| EP0949258A1 (de) | 1999-10-13 |
| EP0949258B1 (de) | 2001-10-31 |
| PT949258E (pt) | 2002-04-29 |
| US5994393A (en) | 1999-11-30 |
| CA2265276C (en) | 2009-09-08 |
| IN186598B (enExample) | 2001-10-06 |
| DE59900364D1 (de) | 2001-12-06 |
| DK0949258T3 (da) | 2002-01-28 |
| ES2164474T3 (es) | 2002-02-16 |
| CA2265276A1 (en) | 1999-09-11 |
| DE19810336A1 (de) | 1999-09-23 |
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