CY1105975T1 - Στοματικες συνθεσεις για την θepαπεια παχυσαρκων, μη διαβητικων θηλαστικων, πepιλαμβανομενων των ανθρωπων - Google Patents
Στοματικες συνθεσεις για την θepαπεια παχυσαρκων, μη διαβητικων θηλαστικων, πepιλαμβανομενων των ανθρωπωνInfo
- Publication number
- CY1105975T1 CY1105975T1 CY20071100138T CY071100138T CY1105975T1 CY 1105975 T1 CY1105975 T1 CY 1105975T1 CY 20071100138 T CY20071100138 T CY 20071100138T CY 071100138 T CY071100138 T CY 071100138T CY 1105975 T1 CY1105975 T1 CY 1105975T1
- Authority
- CY
- Cyprus
- Prior art keywords
- obese
- obesity
- diabetic
- mammals
- treatment
- Prior art date
Links
- 241000124008 Mammalia Species 0.000 title abstract 4
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 4
- 238000011282 treatment Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 2
- 208000008589 Obesity Diseases 0.000 abstract 3
- 235000020824 obesity Nutrition 0.000 abstract 3
- 206010033307 Overweight Diseases 0.000 abstract 2
- 230000037213 diet Effects 0.000 abstract 2
- 235000005911 diet Nutrition 0.000 abstract 2
- QWMFKVNJIYNWII-UHFFFAOYSA-N 5-bromo-2-(2,5-dimethylpyrrol-1-yl)pyridine Chemical compound CC1=CC=C(C)N1C1=CC=C(Br)C=N1 QWMFKVNJIYNWII-UHFFFAOYSA-N 0.000 abstract 1
- 206010013709 Drug ineffective Diseases 0.000 abstract 1
- 230000003579 anti-obesity Effects 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 238000010172 mouse model Methods 0.000 abstract 1
- 238000013116 obese mouse model Methods 0.000 abstract 1
- 239000008203 oral pharmaceutical composition Substances 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- XMVONEAAOPAGAO-UHFFFAOYSA-N sodium tungstate Chemical compound [Na+].[Na+].[O-][W]([O-])(=O)=O XMVONEAAOPAGAO-UHFFFAOYSA-N 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- PBYZMCDFOULPGH-UHFFFAOYSA-N tungstate Chemical compound [O-][W]([O-])(=O)=O PBYZMCDFOULPGH-UHFFFAOYSA-N 0.000 abstract 1
- -1 tungsten (VI) compound Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Child & Adolescent Psychology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Στοματικές φαρμακευτικές συνθέσεις που περιέχουν αποτελεσματική ποσότητα ένωσης βολφραμίου (VI), κατά προτίμηση βολφραμικού άλατος, και ιδανικά βολφραμικού νατρίου (Na2WΟ4), οι οποίες χρησιμεύουν στην αντιμετώπιση της παχυσαρκίας/υπέρβαρου σε μη διαβητικά θηλαστικά, περιλαμβανομένων των ανθρώπων. Αξιολογήθηκε η αποτελεσματικότητα του διένυδρου βολφραμικού νατρίου κατά της παχυσαρκίας σε μοντέλο με ποντίκια που έχουν καταστεί παχύσαρκα κατόπιν διατροφής πάχυνσης, που ονομάζεται "cafeteria diet". Αυτά τα παχύσαρκα ποντίκια είναι ένα καλό μοντέλο μη διαβητικών, παχύσαρκων θηλαστικών, περιλαμβανομένων των ανθρώπων. Η προφυλακτική, θεραπευτική ή/και κοσμετική θεραπεία της παχυσαρκίας που προκύπτει από αυτή την εφεύρεση είναι εντυπωσιακή και υπερτερεί έναντι θεραπειών που έχουν προταθεί στο παρελθόν, καθώς διαθέτει πλεονεκτήματα όπως αποτελεσματικότητα, έλλειψη τοξικότητας και σχετικά χαμηλή τιμή. Επομένως, οι στοματικές συνθέσεις της παρούσας εφεύρεσης είναι χρήσιμες για την στοματική θεραπεία της παχυσαρκίας/υπέρβαρου σε μη διαβητικά θηλαστικά, περιλαμβανομένων των ανθρώπων.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200101200A ES2187276B1 (es) | 2001-05-16 | 2001-05-16 | Composiciones orales para el tratamiento de humanos obesos y no diabeticos. |
| PCT/ES2002/000231 WO2002098435A1 (es) | 2001-05-16 | 2002-05-16 | Composiciones orales para el tratamiento de mamíferos obesos y no diabéticos, incluyendo humanos |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1105975T1 true CY1105975T1 (el) | 2011-04-06 |
Family
ID=8497838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20071100138T CY1105975T1 (el) | 2001-05-16 | 2007-01-31 | Στοματικες συνθεσεις για την θepαπεια παχυσαρκων, μη διαβητικων θηλαστικων, πepιλαμβανομενων των ανθρωπων |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7122209B2 (el) |
| EP (1) | EP1400246B1 (el) |
| AT (1) | ATE344042T1 (el) |
| BR (1) | BR0210975A (el) |
| CA (1) | CA2447141A1 (el) |
| CY (1) | CY1105975T1 (el) |
| DE (1) | DE60215812T2 (el) |
| DK (1) | DK1400246T3 (el) |
| ES (2) | ES2187276B1 (el) |
| PT (1) | PT1400246E (el) |
| WO (1) | WO2002098435A1 (el) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1972342A4 (en) * | 2005-07-29 | 2011-01-12 | Univ Barcelona | PHARMACEUTICAL TREATED SALT (VI) COMPOSITIONS FOR THE TREATMENT OF NEURODEEGENERATIVE DISORDERS, IN PARTICULAR ALZHEIMER DISEASE AND SCHIZOPHRENIA |
| DE102006062250A1 (de) * | 2006-12-22 | 2008-06-26 | Roland Saur-Brosch | Verwendung einer Zusammensetzung aus Mineralstoffen und/oder Vitaminen und gegebenenfalls acetogenen und/oder butyrogenen Bakterien zur oralen oder rektalen Verabreichung für die Behandlung und Vorbeugung von abdominalen Beschwerden |
| CN100515428C (zh) * | 2007-04-26 | 2009-07-22 | 暨南大学 | 钨酸锂在制药中的应用 |
| ES2478790B1 (es) * | 2013-01-22 | 2015-05-06 | Oxolife, S. L. | Uso de sales de tungsteno (VI) para el tratamiento de la infertilidad femenina en mamíferos no diabéticos |
| ES2551828B1 (es) * | 2014-05-21 | 2016-09-12 | Oxolife S.L. | Composiciones alimentarias que comprenden sales de tungsteno (VI) |
| CA2955914C (en) | 2014-07-21 | 2022-09-06 | Ignacio Canals Almazan | Tungsten (vi) salts for use thereof in the treatment of infertility, for favoring normal reproduction and fertility in a non-diabetic female mammal, as well as for improving the efficacy of assisted reproductive techniques |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6025928A (ja) * | 1983-07-21 | 1985-02-08 | Tanaka Seinosuke | 薬剤 |
| DE4018513C1 (el) * | 1989-12-20 | 1991-05-08 | Karl Oexmann, Inh. Wolfgang Oexmann, 4650 Gelsenkirchen, De | |
| US5192197A (en) * | 1991-11-27 | 1993-03-09 | Rockwell International Corporation | Piezoelectric pump |
| CH689836A5 (fr) * | 1994-01-14 | 1999-12-15 | Westonbridge Int Ltd | Micropompe. |
| US5611214A (en) * | 1994-07-29 | 1997-03-18 | Battelle Memorial Institute | Microcomponent sheet architecture |
| US5595763A (en) * | 1995-07-19 | 1997-01-21 | Quimica Farmaceutica Bayer S.A. | Tungsten (VI) compositions for the oral treatment of diabetes mellitus |
| ES2108642B1 (es) * | 1995-07-26 | 1998-08-16 | Quimica Farm Bayer Sa | Composiciones de tungsteno (vi) para el tratamiento oral de la diabetes mellitus. |
| US6148635A (en) * | 1998-10-19 | 2000-11-21 | The Board Of Trustees Of The University Of Illinois | Active compressor vapor compression cycle integrated heat transfer device |
-
2001
- 2001-05-16 ES ES200101200A patent/ES2187276B1/es not_active Expired - Fee Related
-
2002
- 2002-05-16 BR BR0210975-1A patent/BR0210975A/pt not_active IP Right Cessation
- 2002-05-16 EP EP02732763A patent/EP1400246B1/en not_active Expired - Lifetime
- 2002-05-16 CA CA002447141A patent/CA2447141A1/en not_active Abandoned
- 2002-05-16 DE DE60215812T patent/DE60215812T2/de not_active Expired - Fee Related
- 2002-05-16 US US10/477,807 patent/US7122209B2/en not_active Expired - Fee Related
- 2002-05-16 PT PT02732763T patent/PT1400246E/pt unknown
- 2002-05-16 WO PCT/ES2002/000231 patent/WO2002098435A1/es active IP Right Grant
- 2002-05-16 AT AT02732763T patent/ATE344042T1/de not_active IP Right Cessation
- 2002-05-16 DK DK02732763T patent/DK1400246T3/da active
- 2002-05-16 ES ES02732763T patent/ES2275873T3/es not_active Expired - Lifetime
-
2007
- 2007-01-31 CY CY20071100138T patent/CY1105975T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002098435A1 (es) | 2002-12-12 |
| CA2447141A1 (en) | 2002-12-12 |
| DE60215812D1 (de) | 2006-12-14 |
| BR0210975A (pt) | 2004-10-05 |
| PT1400246E (pt) | 2007-02-28 |
| EP1400246A1 (en) | 2004-03-24 |
| DE60215812T2 (de) | 2007-08-30 |
| DK1400246T3 (da) | 2007-03-05 |
| ES2275873T3 (es) | 2007-06-16 |
| US20040131697A1 (en) | 2004-07-08 |
| ATE344042T1 (de) | 2006-11-15 |
| ES2187276B1 (es) | 2004-08-01 |
| EP1400246B1 (en) | 2006-11-02 |
| US7122209B2 (en) | 2006-10-17 |
| ES2187276A1 (es) | 2003-05-16 |
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