CY1105067T1 - Μεθοδος για την παραγωγη νευρωνικου κυτταροϋλικου - Google Patents

Μεθοδος για την παραγωγη νευρωνικου κυτταροϋλικου

Info

Publication number
CY1105067T1
CY1105067T1 CY20061100929T CY061100929T CY1105067T1 CY 1105067 T1 CY1105067 T1 CY 1105067T1 CY 20061100929 T CY20061100929 T CY 20061100929T CY 061100929 T CY061100929 T CY 061100929T CY 1105067 T1 CY1105067 T1 CY 1105067T1
Authority
CY
Cyprus
Prior art keywords
cells
progenitor
progenitor cells
producing
cell
Prior art date
Application number
CY20061100929T
Other languages
English (en)
Inventor
Horst Peschel
Original Assignee
Neuroprogen Gmbh Leipzig
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neuroprogen Gmbh Leipzig filed Critical Neuroprogen Gmbh Leipzig
Publication of CY1105067T1 publication Critical patent/CY1105067T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

Η εφεύρεση σχετίζεται με μεταμοσχεύσιμο νευρωνικό κυτταροϋλικό. Για την αποφυγή ανεπιθύμητων ανοσολογικών παρενεργειών, προτείνεται κυτταροϋλικό το οποίο δεν περιέχει γλοιοκύτταρα σε φυσιολογικώς δραστικά ποσοστά. Μία μέθοδος παραγωγής κυτταροκαλλιέργειας -ικανής για ανάπτυξη- από προγονικά κύτταρα περιλαμβάνει τα ακόλουθα στάδια μεθόδου: αφαίρεση τμήματος του εγκεφάλου ενός θηλαστικού, επιλογή προγονικών κυττάρων, πολλαπλασιασμό των κλώνων προγονικών κυττάρων, ενεργοποίηση των προγονικών κυττάρων προς σχηματισμό καθορισμένων κυττάρων.
CY20061100929T 1999-06-19 2006-07-05 Μεθοδος για την παραγωγη νευρωνικου κυτταροϋλικου CY1105067T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19928210A DE19928210B4 (de) 1999-06-19 1999-06-19 Neuronales Zellmaterial und Verfahren zu dessen Herstellung
PCT/DE2000/001932 WO2000078931A2 (de) 1999-06-19 2000-06-19 Neuronales zellmaterial, verwendung als transplantat und verfahren zu dessen herstellung

Publications (1)

Publication Number Publication Date
CY1105067T1 true CY1105067T1 (el) 2010-03-03

Family

ID=7911909

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20061100929T CY1105067T1 (el) 1999-06-19 2006-07-05 Μεθοδος για την παραγωγη νευρωνικου κυτταροϋλικου

Country Status (10)

Country Link
US (1) US20060099192A1 (el)
EP (1) EP1185625B1 (el)
AT (1) ATE326526T1 (el)
AU (1) AU6424900A (el)
CY (1) CY1105067T1 (el)
DE (2) DE19928210B4 (el)
DK (1) DK1185625T3 (el)
ES (1) ES2259608T3 (el)
PT (1) PT1185625E (el)
WO (1) WO2000078931A2 (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10134667A1 (de) * 2001-07-20 2003-02-06 Neuroprogen Gmbh Leipzig Verfahren zur Herstellung isolierter Zellkulturen, Kulturmedium zur Kultivierung von Zellkulturen und Zellkultur
US8785193B2 (en) * 2006-09-14 2014-07-22 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Dissection tool and methods of use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5082670A (en) * 1988-12-15 1992-01-21 The Regents Of The University Of California Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system
US5411883A (en) * 1989-12-26 1995-05-02 Somatix Therapy Corporation Proliferated neuron progenitor cell product and process
US5750376A (en) * 1991-07-08 1998-05-12 Neurospheres Holdings Ltd. In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny
US5175103A (en) * 1991-10-21 1992-12-29 Trustees Of University Of Pennsylvania Preparation of pure cultures of post-mitotic human neurons
US5753505A (en) * 1995-07-06 1998-05-19 Emory University Neuronal progenitor cells and uses thereof
CA2294737A1 (en) * 1997-07-04 1999-01-14 University Of Utah Research Foundation Neuron-restricted precursor cells
US6165783A (en) * 1997-10-24 2000-12-26 Neuro Spheres Holdings Ltd. Erythropoietin-mediated neurogenesis
US6184035B1 (en) * 1998-11-18 2001-02-06 California Institute Of Technology Methods for isolation and activation of, and control of differentiation from, skeletal muscle stem or progenitor cells
US6610540B1 (en) * 1998-11-18 2003-08-26 California Institute Of Technology Low oxygen culturing of central nervous system progenitor cells

Also Published As

Publication number Publication date
PT1185625E (pt) 2006-07-31
DE19928210A1 (de) 2000-12-21
AU6424900A (en) 2001-01-09
WO2000078931A3 (de) 2001-05-31
ES2259608T3 (es) 2006-10-16
DE50012777D1 (de) 2006-06-22
DE19928210B4 (de) 2005-08-18
EP1185625B1 (de) 2006-05-17
US20060099192A1 (en) 2006-05-11
DK1185625T3 (da) 2006-08-28
EP1185625A2 (de) 2002-03-13
WO2000078931A2 (de) 2000-12-28
ATE326526T1 (de) 2006-06-15

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