Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ip GmbhfiledCriticalBayer Ip Gmbh
Priority claimed from PCT/EP2012/056914external-prioritypatent/WO2012143329A1/en
Publication of CU20130141A7publicationCriticalpatent/CU20130141A7/en
Publication of CU24174B1publicationCriticalpatent/CU24174B1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Nitrogen Condensed Heterocyclic Rings
(AREA)
Abstract
Compuestos de triazolopiridina de la fórmula general (I) donde R^1, R^2, R^3, R^4 y R^5 tienen los valores que se definen en la descrpción y en las reinvindicaciones. Métodos para preparar dichos compuestos. Composiciones y combinaciones farmacéuticas que comprenden dichos compuestos. Uso de dichos compuestos para preparar una composición farmacéuticamente para el tratamiento o la profilaxis de una enfermedad. Compuestos intermediarios útiles para preparar dichos compuestos.Triazolopyridine compounds of the general formula (I) where R ^ 1, R ^ 2, R ^ 3, R ^ 4 and R ^ 5 have the values defined in the description and in the claims. Methods for preparing said compounds. Compositions and pharmaceutical combinations comprising said compounds. Use of said compounds to prepare a pharmaceutical composition for the treatment or prophylaxis of a disease. Intermediate compounds useful for preparing said compounds.
CUP2013000141A2011-04-212012-04-16
TRIAZOLOPIRIDINS AS QUINASE INHIBITORS MPS-1
CU24174B1
(en)
Alkylated piperazine derivative compounds; pharmaceutical composition that includes them; process to prepare the pharmaceutical composition; kit and use in the treatment of immune disorders, cancer, cardiovascular diseases, inflammation, among others.
Pyrazole-derived compounds of formulas (ia) or (ib), crth2 antagonists; pharmaceutical compositions containing them; pharmaceutical combinations; its use in the prevention and / or treatment of inflammatory, infectious and immunoregulatory disorders.
Substituted cyclopentanamide derived compounds; pharmaceutical composition; obtaining process; and use in the treatment or prophylaxis of diabetes, atherosclerosis, among others.
Compounds derived from alkoxycarbonyl-amino-alkynyl-adenosine; pharmaceutical composition comprising them; use of the compound in the preparation of a useful medicine to treat autoimmune, inflammatory, allergic, infectious diseases among others.
Use of ezatiostat or a salt of it for the treatment of myelodysplasic syndrome; pharmaceutical composition comprising said compound in addition to lenalidomide; pharmaceutical combination; Pharmaceutical kit