CS9100077A2 - 2,13-d-disubstituted ergolines and method of their production - Google Patents
2,13-d-disubstituted ergolines and method of their productionInfo
- Publication number
- CS9100077A2 CS9100077A2 CS9177A CS7791A CS9100077A2 CS 9100077 A2 CS9100077 A2 CS 9100077A2 CS 9177 A CS9177 A CS 9177A CS 7791 A CS7791 A CS 7791A CS 9100077 A2 CS9100077 A2 CS 9100077A2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- production
- ergolines
- disubstituted
- disubstituted ergolines
- compounds
- Prior art date
Links
- RHGUXDUPXYFCTE-ZWNOBZJWSA-N ergoline Chemical class C1=CC([C@@H]2[C@H](NCCC2)C2)=C3C2=CNC3=C1 RHGUXDUPXYFCTE-ZWNOBZJWSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
- C07D457/12—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4001323A DE4001323A1 (de) | 1990-01-15 | 1990-01-15 | 2,13-disubstituierte ergoline, deren herstellung und verwendung in arzneimitteln |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS9100077A2 true CS9100077A2 (en) | 1991-10-15 |
| CZ279777B6 CZ279777B6 (cs) | 1995-06-14 |
Family
ID=6398304
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0463139B1 (cs) |
| JP (1) | JPH04504425A (cs) |
| AT (1) | ATE124945T1 (cs) |
| CA (1) | CA2049016A1 (cs) |
| CZ (1) | CZ279777B6 (cs) |
| DE (2) | DE4001323A1 (cs) |
| DK (1) | DK0463139T3 (cs) |
| ES (1) | ES2076517T3 (cs) |
| HU (1) | HUT58093A (cs) |
| WO (1) | WO1991010663A1 (cs) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3587860D1 (de) * | 1984-04-09 | 1994-07-28 | Schering Ag | 2-substituierte Ergolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel. |
| DE3533675A1 (de) * | 1985-09-19 | 1987-03-26 | Schering Ag | Neue 12- und 13-brom-ergolinderivate |
| DE3533672A1 (de) * | 1985-09-19 | 1987-03-26 | Schering Ag | Neue 12- und 13-substituierte ergolinderivate |
| DE3806374A1 (de) * | 1988-02-25 | 1989-09-07 | Schering Ag | Neue ergolin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
-
1990
- 1990-01-15 DE DE4001323A patent/DE4001323A1/de not_active Withdrawn
-
1991
- 1991-01-15 DK DK91902179.0T patent/DK0463139T3/da active
- 1991-01-15 AT AT91902179T patent/ATE124945T1/de not_active IP Right Cessation
- 1991-01-15 ES ES91902179T patent/ES2076517T3/es not_active Expired - Lifetime
- 1991-01-15 HU HU912908A patent/HUT58093A/hu unknown
- 1991-01-15 DE DE59105961T patent/DE59105961D1/de not_active Expired - Fee Related
- 1991-01-15 CA CA002049016A patent/CA2049016A1/en not_active Abandoned
- 1991-01-15 WO PCT/DE1991/000039 patent/WO1991010663A1/de active IP Right Grant
- 1991-01-15 CZ CS9177A patent/CZ279777B6/cs unknown
- 1991-01-15 EP EP91902179A patent/EP0463139B1/de not_active Expired - Lifetime
- 1991-01-15 JP JP3502370A patent/JPH04504425A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DK0463139T3 (da) | 1995-11-06 |
| EP0463139B1 (de) | 1995-07-12 |
| DE4001323A1 (de) | 1991-07-18 |
| CZ279777B6 (cs) | 1995-06-14 |
| ATE124945T1 (de) | 1995-07-15 |
| ES2076517T3 (es) | 1995-11-01 |
| WO1991010663A1 (de) | 1991-07-25 |
| DE59105961D1 (de) | 1995-08-17 |
| CA2049016A1 (en) | 1991-07-16 |
| HUT58093A (en) | 1992-01-28 |
| EP0463139A1 (de) | 1992-01-02 |
| JPH04504425A (ja) | 1992-08-06 |
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