CS316491A3 - Derivatives of amino acids, process of their preparation and pharmaceuticals based thereon - Google Patents
Derivatives of amino acids, process of their preparation and pharmaceuticals based thereonInfo
- Publication number
- CS316491A3 CS316491A3 CS913164A CS316491A CS316491A3 CS 316491 A3 CS316491 A3 CS 316491A3 CS 913164 A CS913164 A CS 913164A CS 316491 A CS316491 A CS 316491A CS 316491 A3 CS316491 A3 CS 316491A3
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- derivatives
- preparation
- amino acids
- pharmaceuticals based
- pharmaceuticals
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/14—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/08—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Endocrinology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4033062A DE4033062A1 (en) | 1990-10-18 | 1990-10-18 | AMINOSAEUREDERIVATE |
Publications (1)
Publication Number | Publication Date |
---|---|
CS316491A3 true CS316491A3 (en) | 1992-05-13 |
Family
ID=6416535
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS913164A CS316491A3 (en) | 1990-10-18 | 1991-10-18 | Derivatives of amino acids, process of their preparation and pharmaceuticals based thereon |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0481311A3 (en) |
JP (1) | JPH04316548A (en) |
KR (1) | KR920008066A (en) |
AU (1) | AU8587791A (en) |
CA (1) | CA2053573A1 (en) |
CS (1) | CS316491A3 (en) |
DE (1) | DE4033062A1 (en) |
HU (1) | HU913277D0 (en) |
IE (1) | IE913650A1 (en) |
PT (1) | PT99262A (en) |
ZA (1) | ZA918294B (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8927913D0 (en) * | 1989-12-11 | 1990-02-14 | Hoffmann La Roche | Amino acid derivatives |
US6825169B1 (en) | 1991-10-22 | 2004-11-30 | Trustees Of Tufts College | Inhibitors of dipeptidyl-aminopeptidase type IV |
US6071895A (en) * | 1992-03-11 | 2000-06-06 | Narhex Limited | Polar-substituted hydrocarbons |
ATE253050T1 (en) | 1992-03-11 | 2003-11-15 | Narhex Ltd | AMINE DERIVATIVES OF OXO- AND HYDROXY-SUBSTITUTED HYDROCARBONS |
RU2126794C1 (en) * | 1992-03-11 | 1999-02-27 | Нархекс Лимитед | Amino-derivatives of oxo- or hydroxy-substituted hydrazines, method of their synthesis and pharmaceutical compositions for inhibition of retrovirus protease |
US5888992A (en) * | 1992-03-11 | 1999-03-30 | Narhex Limited | Polar substituted hydrocarbons |
DE4322811A1 (en) * | 1992-07-08 | 1994-02-10 | Duerrwaechter E Dr Doduco | Low-current signal transmission system esp. on vehicular wiring |
IL110898A0 (en) * | 1993-09-10 | 1994-11-28 | Narhex Australia Pty Ltd | Polar-substituted hydrocarbons |
US5965532A (en) | 1996-06-28 | 1999-10-12 | Trustees Of Tufts College | Multivalent compounds for crosslinking receptors and uses thereof |
US6100234A (en) | 1997-05-07 | 2000-08-08 | Tufts University | Treatment of HIV |
US6040145A (en) | 1997-05-07 | 2000-03-21 | Tufts University | Potentiation of the immune response |
ATE357509T1 (en) | 1997-09-29 | 2007-04-15 | Point Therapeutics Inc | STIMULATION OF HEMATOPOIETIC CELLS IN VITRO |
EP1075266A1 (en) | 1998-05-04 | 2001-02-14 | Point Therapeutics, Inc. | Hematopoietic stimulation |
US6890904B1 (en) | 1999-05-25 | 2005-05-10 | Point Therapeutics, Inc. | Anti-tumor agents |
GB0505221D0 (en) * | 2005-03-14 | 2005-04-20 | Southampton Polypeptides | Process |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0249096B1 (en) * | 1986-06-10 | 1995-01-11 | Merck Patent Gmbh | Renin-inhibiting amino acid derivatives. |
DE3717631A1 (en) * | 1987-05-26 | 1988-12-15 | Merck Patent Gmbh | AMINO ACID DERIVATIVES |
DE3931585A1 (en) * | 1989-09-22 | 1991-04-04 | Merck Patent Gmbh | AMINOSAEUREDERIVATE |
-
1990
- 1990-10-18 DE DE4033062A patent/DE4033062A1/en not_active Withdrawn
-
1991
- 1991-10-05 EP EP19910117014 patent/EP0481311A3/en not_active Withdrawn
- 1991-10-15 KR KR1019910018096A patent/KR920008066A/en not_active Application Discontinuation
- 1991-10-15 AU AU85877/91A patent/AU8587791A/en not_active Abandoned
- 1991-10-16 CA CA002053573A patent/CA2053573A1/en not_active Abandoned
- 1991-10-17 IE IE365091A patent/IE913650A1/en not_active Application Discontinuation
- 1991-10-17 ZA ZA918294A patent/ZA918294B/en unknown
- 1991-10-17 HU HU913277A patent/HU913277D0/en unknown
- 1991-10-17 PT PT99262A patent/PT99262A/en not_active Application Discontinuation
- 1991-10-18 JP JP3333849A patent/JPH04316548A/en active Pending
- 1991-10-18 CS CS913164A patent/CS316491A3/en unknown
Also Published As
Publication number | Publication date |
---|---|
ZA918294B (en) | 1992-07-29 |
PT99262A (en) | 1992-08-31 |
IE913650A1 (en) | 1992-04-22 |
AU8587791A (en) | 1992-04-30 |
CA2053573A1 (en) | 1992-04-19 |
EP0481311A2 (en) | 1992-04-22 |
HU913277D0 (en) | 1992-01-28 |
DE4033062A1 (en) | 1992-04-23 |
JPH04316548A (en) | 1992-11-06 |
EP0481311A3 (en) | 1992-11-19 |
KR920008066A (en) | 1992-05-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CS189391A3 (en) | Dialkoxypiridylbenzimidazole derivatives, process of their preparation and their pharmaceutical use | |
HK18796A (en) | New amino acid derivatives processes for the preparation thereof and pharmaceutical composition comprising the same | |
IL93569A0 (en) | Amino acid derivatives,their preparation and medicaments comprising them | |
CS316491A3 (en) | Derivatives of amino acids, process of their preparation and pharmaceuticals based thereon | |
CS331491A3 (en) | Cyclopeptides, process of their preparation and pharmaceuticals based thereon | |
PL326081A1 (en) | Novel derivatives of amino acids, their production and application | |
CS202292A3 (en) | Novel pyrrolopyrazines, process of their preparation and medicaments based thereon | |
CS299991A3 (en) | Derivatives of 2-aminopyrimidine-4-carboxamide, process of their preparation and their application as medicaments | |
IL105100A0 (en) | Glutamic acid derivatives and process for their preparation | |
EP0425925A3 (en) | Substituted amino acid amide derivatives, their preparation and use | |
AU649546B2 (en) | Dicarboxylic acid derivatives and process for preparation thereof | |
CS382891A3 (en) | N-arylpiperizinealkaneamide derivatives, process of their preparation and pharmaceuticals based thereon | |
CZ78095A3 (en) | Novel 17 beta-substituted derivatives of 4-azaandrostane, pharmaceutical preparations based thereon and process of their preparation | |
LTIP760A (en) | Novel thienothiazine derivatives, process for preparing thereof and pharmaceutical preparations | |
AU1028892A (en) | Phenoxyalkylcarboxylic acid derivatives and process of preparing the same | |
HU896135D0 (en) | Process for the preparation of 2-azabicyclo [2.2.1] hept-5-en-2-acetic acid and derivatives thereof | |
IL67366A0 (en) | N-(vinblastinoyl-23)derivatives of amino acids,their preparation and therapeutical application | |
CS382191A3 (en) | Benzoxazol- and benzothiazolamine derivatives, process of their preparation and pharmaceuticals based thereon | |
ZA918863B (en) | Substituted amino acid derivatives their preparation and use | |
HU912979D0 (en) | New amino acid derivatives and method for producing them | |
CS259991A3 (en) | Amino acids derivatives, process of their preparation and pharmaceuticals prepared therefrom | |
ZA917518B (en) | Substituted amino acid derivatives their preparation and use | |
CS377591A3 (en) | Acid amides, process of their preparation and pharmaceutical compositionsbased thereon | |
HU8902302D0 (en) | Process for preparation of 1,2-hydroxy-phosphonates and derivatives thereof | |
AU7781991A (en) | Diastereoselective process for preparing n-substituted amino acids and derivatives |