CS274890B2 - Method of oxetanocine derivative preparation - Google Patents
Method of oxetanocine derivative preparationInfo
- Publication number
- CS274890B2 CS274890B2 CS59588A CS59588A CS274890B2 CS 274890 B2 CS274890 B2 CS 274890B2 CS 59588 A CS59588 A CS 59588A CS 59588 A CS59588 A CS 59588A CS 274890 B2 CS274890 B2 CS 274890B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- oxetanocine
- compound
- general formula
- derivative preparation
- preparation
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229940095054 ammoniac Drugs 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000001506 immunosuppresive effect Effects 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- LMJVXGOFWKVXAW-OXOINMOOSA-N oxetanocin A Chemical class C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@H]1CO LMJVXGOFWKVXAW-OXOINMOOSA-N 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The method of preparation of oxetanocin derivative of formula I consists in the fact that the compound of general formula III, where X1 means protected hydroxyl group or atom of halogen and R1 means protecting group, reacts with ammoniac in presence of inert solvent at a temperature of 0 to 200 degrees C. The compound of general formula I, as well as its physiologically acceptable salts, has mainly immunosuppressive and antiviral effects.<IMAGE>
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12015987 | 1987-05-19 | ||
CS340888A CS274627B2 (en) | 1987-05-19 | 1988-05-19 | Method of oxetanocine derivative preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
CS59588A2 CS59588A2 (en) | 1990-12-13 |
CS274890B2 true CS274890B2 (en) | 1991-11-12 |
Family
ID=25745805
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS59588A CS274890B2 (en) | 1987-05-19 | 1988-05-19 | Method of oxetanocine derivative preparation |
Country Status (1)
Country | Link |
---|---|
CS (1) | CS274890B2 (en) |
-
1988
- 1988-05-19 CS CS59588A patent/CS274890B2/en unknown
Also Published As
Publication number | Publication date |
---|---|
CS59588A2 (en) | 1990-12-13 |
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