CS215487B1 - N, N'-bis (alkylmethyl) -1,2-ethanediamine dioxides and their preparation - Google Patents
N, N'-bis (alkylmethyl) -1,2-ethanediamine dioxides and their preparation Download PDFInfo
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- CS215487B1 CS215487B1 CS105781A CS105781A CS215487B1 CS 215487 B1 CS215487 B1 CS 215487B1 CS 105781 A CS105781 A CS 105781A CS 105781 A CS105781 A CS 105781A CS 215487 B1 CS215487 B1 CS 215487B1
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Abstract
Vynález sa týká N,N'-bis(alkylmetyl)-l,2-etándiamíndioxidov všeobecného vzorca 9 9 R - N - CH2 - CH2 - N - R OH CH 5 3 kde R značí 8 až 14 atomov uhlíka v alkylovom reťazci a sposobu přípravy týchto zlúčenín z N,N'- bis(alkylmetyl)-l,2-etándiamínov oxidáciou vodným roztokom peroxidu vodíka. Finálně zlúčeniny majú výrazný antimikrobiálny účinok ako i povrchovoaktívne vlastnosti.The invention relates to N,N'-bis(alkylmethyl)-1,2-ethanediamine dioxides of the general formula 9 9 R - N - CH2 - CH2 - N - R OH CH 5 3 where R denotes 8 to 14 carbon atoms in the alkyl chain and to a method of preparing these compounds from N,N'-bis(alkylmethyl)-1,2-ethanediamines by oxidation with an aqueous solution of hydrogen peroxide. Finally, the compounds have a significant antimicrobial effect as well as surface-active properties.
Description
Vynález sa týká N,N'-bis(alkylmetyl)-l,2-etándiamíndioxidov všeobecného vzorcaThe invention relates to N, N'-bis (alkylmethyl) -1,2-ethanediamine dioxides of the general formula
R - N - CH- - CH- - N - R ( 2 R ,R - N - CH - CH - N - R ( 2 R,
CH5 ch5 kde R značí alkylový reťazec s počtom atómov uhlíka 8 až 14.CH 5 CH 5 wherein R is an alkyl chain having a carbon number 8 to 14.
Z hlediska antimikrobiálnej účinnosti patria nearomatické amínoxidy, ktoré vo svojej molekule obsahujú najmenej jeden dlhý alkylový reťazec medzi účinné zlúčeniny. Okrem biologického účinku vykazuj ú tieto látky aj povrchovoaktívne vlastnosti.In terms of antimicrobial activity, non-aromatic amine oxides which contain at least one long alkyl chain in their molecule are among the active compounds. In addition to their biological activity, they also have surface-active properties.
Doteraz sú známe amínoxidy odvodené od 1,2-etándiamínu typu Ν,Ν'-bisdialkyl, kde alkylový reťazec obsahuje 1 alebo 2 atomy uhlíka. Tieto zlúčeniny sú však antimikrobiálne ako i z hladiska povrchovej aktivity neúčinné.Hitherto known amine oxides are derived from 1,2-ethanediamine of the Ν, Ν'-bisdialkyl type wherein the alkyl chain contains 1 or 2 carbon atoms. However, these compounds are ineffective as well as antimicrobial and surface active.
Zlúčeniny, ktoré sú predmetom vynálezu, sú látky nové, doteraz v chemickej literatúre neopísané, u ktorých sa zistili doteraz neznáme účinky na mikroorganizmy.The compounds of the invention are novel substances which have not been previously described in the chemical literature and have been found to have unknown effects on microorganisms.
V príkladoch sú uvedené vybrané zlúčeniny, ktoré sú predmetom vynálezu a metoda ich přípravy ako i ich charakterizácia spolu s uvedením ich antimikrobiálnej účinnosti (udanej ako minimálnaThe examples show selected compounds of the invention and methods for their preparation as well as their characterization together with an indication of their antimicrobial activity (given as the minimum
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CS105781A CS215487B1 (en) | 1981-02-16 | 1981-02-16 | N, N'-bis (alkylmethyl) -1,2-ethanediamine dioxides and their preparation |
Applications Claiming Priority (1)
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CS105781A CS215487B1 (en) | 1981-02-16 | 1981-02-16 | N, N'-bis (alkylmethyl) -1,2-ethanediamine dioxides and their preparation |
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CS215487B1 true CS215487B1 (en) | 1982-08-27 |
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CS105781A CS215487B1 (en) | 1981-02-16 | 1981-02-16 | N, N'-bis (alkylmethyl) -1,2-ethanediamine dioxides and their preparation |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109721511A (en) * | 2019-01-21 | 2019-05-07 | 北京工商大学 | A kind of preparation method of the Shuangzi amine oxide of the ethyl of ester group containing alkyl |
JP2021109839A (en) * | 2020-01-08 | 2021-08-02 | 株式会社ニイタカ | Gemini compound |
-
1981
- 1981-02-16 CS CS105781A patent/CS215487B1/en unknown
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109721511A (en) * | 2019-01-21 | 2019-05-07 | 北京工商大学 | A kind of preparation method of the Shuangzi amine oxide of the ethyl of ester group containing alkyl |
JP2021109839A (en) * | 2020-01-08 | 2021-08-02 | 株式会社ニイタカ | Gemini compound |
JP7432185B2 (en) | 2020-01-08 | 2024-02-16 | 株式会社ニイタカ | gemini type compound |
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