CS193563B2 - Process for preparing steric uniform cis-and trans-5,6-alkylen-5,6-dihydropyrimidin-4/3h/-ones - Google Patents
Process for preparing steric uniform cis-and trans-5,6-alkylen-5,6-dihydropyrimidin-4/3h/-onesInfo
- Publication number
- CS193563B2 CS193563B2 CS766408A CS640876A CS193563B2 CS 193563 B2 CS193563 B2 CS 193563B2 CS 766408 A CS766408 A CS 766408A CS 640876 A CS640876 A CS 640876A CS 193563 B2 CS193563 B2 CS 193563B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- dihydropyrimidin
- alkylen
- trans
- ones
- cis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU75CI00001614A HU172460B (hu) | 1975-10-03 | 1975-10-03 | Sposob poluchenija novykh proizvodnykh 5,6-digidro-3h-pirimidin-4-ona |
Publications (1)
Publication Number | Publication Date |
---|---|
CS193563B2 true CS193563B2 (en) | 1979-10-31 |
Family
ID=10994582
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS766408A CS193563B2 (en) | 1975-10-03 | 1976-10-04 | Process for preparing steric uniform cis-and trans-5,6-alkylen-5,6-dihydropyrimidin-4/3h/-ones |
Country Status (14)
Country | Link |
---|---|
US (1) | US4113868A (ru) |
JP (1) | JPS5257185A (ru) |
AU (1) | AU507798B2 (ru) |
CH (2) | CH626072A5 (ru) |
CS (1) | CS193563B2 (ru) |
DD (1) | DD127444A1 (ru) |
DE (1) | DE2643384A1 (ru) |
FI (1) | FI66603C (ru) |
FR (1) | FR2326193A1 (ru) |
GB (1) | GB1559985A (ru) |
HU (1) | HU172460B (ru) |
IL (1) | IL50577A (ru) |
PL (2) | PL110639B1 (ru) |
SU (1) | SU627752A3 (ru) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU179687B (en) * | 1978-11-01 | 1982-11-29 | Chinoin Gyogyszer Es Vegyeszet | Process for producing 5,6,7,8-- etrahydro-4-bracket-3h-bracket closed-quinasolinones |
US4814335A (en) * | 1982-12-30 | 1989-03-21 | Biomeasure, Incorporated | Antiviral compounds |
JPS59210071A (ja) * | 1982-12-30 | 1984-11-28 | バイオメジヤ−・インコ−ポレ−テツド | 抗ウイルス作用を有する化合物 |
US5629264A (en) * | 1995-03-23 | 1997-05-13 | Rohm And Haas Company | 2-aryl-5,6-dihydropyrimidinones and herbicidal use thereof |
AU2004200A (en) * | 1999-01-14 | 2000-08-01 | Meiji Seika Kaisha Ltd. | Poly(adp-ribose) polymerase inhibitors consisting of pyrimidine derivatives |
DE10123163A1 (de) * | 2001-05-09 | 2003-01-16 | Gruenenthal Gmbh | Substituierte Cyclohexan-1,4-diaminderivate |
AUPS019702A0 (en) * | 2002-01-29 | 2002-02-21 | Fujisawa Pharmaceutical Co., Ltd. | Condensed heterocyclic compounds |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3047462A (en) * | 1959-03-06 | 1962-07-31 | Lab Jacques Logeais Soc D Expl | Quinazolone anti-inflammatory composition |
GB1233943A (ru) * | 1968-10-31 | 1971-06-03 | ||
US3696102A (en) * | 1970-03-09 | 1972-10-03 | Pfizer & Co C | Process for the synthesis of substituted quinazolin-4-ones |
US3996227A (en) * | 1971-07-08 | 1976-12-07 | Sandoz, Inc. | 7-Methyl-1-isopropyl-4-phenyl-5,6,7,8-tetrahydro-2(1H)-quinazolinone |
US3945960A (en) * | 1973-07-26 | 1976-03-23 | Sandoz, Inc. | Antiinflammatory and analgesic cycloalkano-pyrimidin-2(1H)-ones |
US3994894A (en) * | 1975-01-08 | 1976-11-30 | Sandoz, Inc. | Cyclopentano[1,2-c]pyrimidin-2(1H)-ones |
-
1975
- 1975-10-03 HU HU75CI00001614A patent/HU172460B/hu unknown
-
1976
- 1976-09-27 DE DE19762643384 patent/DE2643384A1/de not_active Ceased
- 1976-09-29 AU AU18203/76A patent/AU507798B2/en not_active Expired
- 1976-09-29 IL IL50577A patent/IL50577A/xx unknown
- 1976-09-29 US US05/728,459 patent/US4113868A/en not_active Expired - Lifetime
- 1976-10-01 FR FR7629634A patent/FR2326193A1/fr active Granted
- 1976-10-01 FI FI762806A patent/FI66603C/fi not_active IP Right Cessation
- 1976-10-01 DD DD195094A patent/DD127444A1/xx unknown
- 1976-10-01 CH CH1248376A patent/CH626072A5/de not_active IP Right Cessation
- 1976-10-03 SU SU762406052A patent/SU627752A3/ru active
- 1976-10-04 CS CS766408A patent/CS193563B2/cs unknown
- 1976-10-04 JP JP51118627A patent/JPS5257185A/ja active Pending
- 1976-10-04 PL PL1976192823A patent/PL110639B1/pl unknown
- 1976-10-04 PL PL1976213570A patent/PL111251B1/pl unknown
- 1976-10-04 GB GB41104/76A patent/GB1559985A/en not_active Expired
-
1980
- 1980-10-08 CH CH752880A patent/CH626074A5/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FI762806A (ru) | 1977-04-04 |
PL111251B1 (en) | 1980-08-30 |
GB1559985A (en) | 1980-01-30 |
SU627752A3 (ru) | 1978-10-05 |
FR2326193B1 (ru) | 1979-09-28 |
US4113868A (en) | 1978-09-12 |
FR2326193A1 (fr) | 1977-04-29 |
PL110639B1 (en) | 1980-07-31 |
AU507798B2 (en) | 1980-02-28 |
JPS5257185A (en) | 1977-05-11 |
CH626074A5 (ru) | 1981-10-30 |
HU172460B (hu) | 1978-09-28 |
IL50577A (en) | 1979-12-30 |
AU1820376A (en) | 1978-04-06 |
DD127444A1 (ru) | 1977-09-21 |
FI66603B (fi) | 1984-07-31 |
DE2643384A1 (de) | 1977-06-02 |
IL50577A0 (en) | 1976-11-30 |
FI66603C (fi) | 1984-11-12 |
CH626072A5 (ru) | 1981-10-30 |
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