CS178940B2 - Method for production of arylacetylene compounds - Google Patents

Method for production of arylacetylene compounds

Info

Publication number
CS178940B2
CS178940B2 CS7400008969A CS896974A CS178940B2 CS 178940 B2 CS178940 B2 CS 178940B2 CS 7400008969 A CS7400008969 A CS 7400008969A CS 896974 A CS896974 A CS 896974A CS 178940 B2 CS178940 B2 CS 178940B2
Authority
CS
Czechoslovakia
Prior art keywords
production
arylacetylene
compounds
arylacetylene compounds
Prior art date
Application number
CS7400008969A
Other languages
Czech (cs)
English (en)
Inventor
Winston S Marshall
William Pfeifer
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CS178940B2 publication Critical patent/CS178940B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C25/00—Compounds containing at least one halogen atom bound to a six-membered aromatic ring
    • C07C25/24—Halogenated aromatic hydrocarbons with unsaturated side chains
    • C07C25/28—Halogenated styrenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A61K31/015—Hydrocarbons carbocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C15/00—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts
    • C07C15/40—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts substituted by unsaturated carbon radicals
    • C07C15/42—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts substituted by unsaturated carbon radicals monocyclic
    • C07C15/48—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts substituted by unsaturated carbon radicals monocyclic the hydrocarbon substituent containing a carbon-to-carbon triple bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C15/00—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts
    • C07C15/40—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts substituted by unsaturated carbon radicals
    • C07C15/50—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts substituted by unsaturated carbon radicals polycyclic non-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/013—Preparation of halogenated hydrocarbons by addition of halogens
    • C07C17/02—Preparation of halogenated hydrocarbons by addition of halogens to unsaturated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/18—Preparation of halogenated hydrocarbons by replacement by halogens of oxygen atoms of carbonyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/25—Preparation of halogenated hydrocarbons by splitting-off hydrogen halides from halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C25/00—Compounds containing at least one halogen atom bound to a six-membered aromatic ring
    • C07C25/24—Halogenated aromatic hydrocarbons with unsaturated side chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CS7400008969A 1973-12-26 1974-12-23 Method for production of arylacetylene compounds CS178940B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/428,163 US3991212A (en) 1973-12-26 1973-12-26 Anti-inflammatory agents

Publications (1)

Publication Number Publication Date
CS178940B2 true CS178940B2 (en) 1977-10-31

Family

ID=23697797

Family Applications (1)

Application Number Title Priority Date Filing Date
CS7400008969A CS178940B2 (en) 1973-12-26 1974-12-23 Method for production of arylacetylene compounds

Country Status (22)

Country Link
US (1) US3991212A (ro)
JP (1) JPS5096547A (ro)
AR (1) AR203222A1 (ro)
AT (1) AT334353B (ro)
AU (1) AU7651274A (ro)
BE (1) BE823810A (ro)
BG (1) BG25982A3 (ro)
CA (1) CA1158677A (ro)
CH (1) CH614919A5 (ro)
CS (1) CS178940B2 (ro)
DD (1) DD117442A5 (ro)
DE (1) DE2459452A1 (ro)
DK (1) DK664974A (ro)
ES (1) ES433293A1 (ro)
FR (1) FR2255892B1 (ro)
HU (1) HU169307B (ro)
NL (1) NL7416851A (ro)
PL (1) PL99360B1 (ro)
RO (1) RO71806A (ro)
SE (1) SE7415848L (ro)
SU (1) SU543339A3 (ro)
ZA (1) ZA748000B (ro)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3981932A (en) * 1972-07-03 1976-09-21 William H. Rorer, Inc. Ethynylbenzene compounds and derivatives thereof
US4093737A (en) * 1972-07-03 1978-06-06 William H. Rorer, Inc. Ethynylbenzene compounds and derivatives thereof in the treatment of pain, fever or inflammation
US4157449A (en) * 1974-01-07 1979-06-05 William H. Rorer, Inc. Ethynylbenzene compounds and derivatives thereof
US4120885A (en) * 1975-05-14 1978-10-17 William H. Rorer, Inc. Ethynylbenzene compounds and derivatives thereof
US4528114A (en) * 1981-12-18 1985-07-09 Hoffmann-La Roche Inc. Acetylenes
US4665246A (en) * 1984-03-09 1987-05-12 Chem Biochem Research, Inc. Method of producing ethynyl aromatic compounds
CA2450073C (en) 2001-07-25 2017-08-29 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
EP2671508B1 (en) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-informatics system
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質(rap)結合体の投与による肝障害の処置
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
KR20180114970A (ko) 2009-05-06 2018-10-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3852364A (en) 1972-07-03 1974-12-03 Rorer Inc William H Ethynylbenzene compounds derivatives therefor

Also Published As

Publication number Publication date
DD117442A5 (ro) 1976-01-12
CA1158677A (en) 1983-12-13
AT334353B (de) 1976-01-10
BE823810A (fr) 1975-06-24
PL99360B1 (pl) 1978-07-31
CH614919A5 (ro) 1979-12-28
RO71806A (ro) 1982-02-26
FR2255892B1 (ro) 1978-07-21
NL7416851A (nl) 1975-06-30
SU543339A3 (ru) 1977-01-15
ES433293A1 (es) 1976-12-01
JPS5096547A (ro) 1975-07-31
ZA748000B (en) 1976-07-28
US3991212A (en) 1976-11-09
DK664974A (ro) 1975-08-25
BG25982A3 (bg) 1979-01-12
HU169307B (ro) 1976-11-28
FR2255892A1 (ro) 1975-07-25
ATA1021474A (de) 1976-05-15
AR203222A1 (es) 1975-08-22
DE2459452A1 (de) 1975-07-31
SE7415848L (ro) 1975-06-27
AU7651274A (en) 1976-06-17

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