CR8567A - HETEROARIL-Y FENILSULFAMOILO SUBSTITUTED COMPOUNDS - Google Patents
HETEROARIL-Y FENILSULFAMOILO SUBSTITUTED COMPOUNDSInfo
- Publication number
- CR8567A CR8567A CR8567A CR8567A CR8567A CR 8567 A CR8567 A CR 8567A CR 8567 A CR8567 A CR 8567A CR 8567 A CR8567 A CR 8567A CR 8567 A CR8567 A CR 8567A
- Authority
- CR
- Costa Rica
- Prior art keywords
- compounds
- cholesterol
- levels
- ldl
- triglycerides
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Quinoline Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
La presente invencion se refiere a compuestos heteroaril- y fenilsulfamoilo sustituidos, a composiciones farmaceuticas que contienen tales compuestos y al uso de tales compuestos como agonistas del recpetor activador del proliferador de peroxisoma (PPAR). Los activadores de PPAR alfa, composiciones farmaceuticas que contienen dichos compuestos y el uso de dichos compuestos para elevar cietos niveles de lipidos en plasma, incluyendo el colesterol de lipoproteinas de alta densidad y para disminuir otros ciertos niveles de lipidos en plasma, tales como colesterol- LDL y trigliceridos y por consiguiente para tratar enfermedades que se agravan por bajos niveles de colesterol- HDL y/o altos niveles de colesterol-LDL y trigliceridos, tales como aterosclerosis y enfermedades cardiovasculares, en mamiferos, incluyendo seres humanos. Los compuestos tambien son utiles para el tratamiento del balance energetico negativo (NEB) y enfermedades asociadas en rumiantes.The present invention relates to substituted heteroaryl- and phenylsulfamoyl compounds, pharmaceutical compositions containing such compounds and the use of such compounds as agonists of the peroxisome proliferator activator receptor (PPAR). PPAR alpha activators, pharmaceutical compositions containing said compounds and the use of said compounds to raise certain levels of plasma lipids, including high-density lipoprotein cholesterol and to decrease other certain levels of plasma lipids, such as cholesterol- LDL and triglycerides and therefore to treat diseases that are aggravated by low levels of cholesterol-HDL and / or high levels of cholesterol-LDL and triglycerides, such as atherosclerosis and cardiovascular diseases, in mammals, including humans. The compounds are also useful for the treatment of negative energy balance (NEB) and associated diseases in ruminants.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55211404P | 2004-03-10 | 2004-03-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR8567A true CR8567A (en) | 2006-10-17 |
Family
ID=37859499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR8567A CR8567A (en) | 2004-03-10 | 2006-08-24 | HETEROARIL-Y FENILSULFAMOILO SUBSTITUTED COMPOUNDS |
Country Status (5)
| Country | Link |
|---|---|
| CN (1) | CN1930121A (en) |
| CR (1) | CR8567A (en) |
| GT (1) | GT200500042A (en) |
| TN (1) | TNSN06269A1 (en) |
| ZA (1) | ZA200606597B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019029211A1 (en) * | 2017-08-10 | 2019-02-14 | 上海交通大学医学院 | Compound used as sirt6 small-molecule allosteric activator and pharmaceutical composition thereof |
| CN109384694B (en) * | 2017-08-10 | 2022-04-05 | 上海爱乐维生物科技有限公司 | SIRT6 small-molecule agonist and application thereof |
-
2005
- 2005-02-28 CN CN 200580007622 patent/CN1930121A/en active Pending
- 2005-03-09 GT GT200500042A patent/GT200500042A/en unknown
-
2006
- 2006-08-08 ZA ZA200606597A patent/ZA200606597B/en unknown
- 2006-08-24 CR CR8567A patent/CR8567A/en not_active Application Discontinuation
- 2006-09-08 TN TNP2006000269A patent/TNSN06269A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GT200500042A (en) | 2005-10-24 |
| TNSN06269A1 (en) | 2007-12-03 |
| CN1930121A (en) | 2007-03-14 |
| ZA200606597B (en) | 2007-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal (granting procedure) |