CR20190012A - SPECIFIC ANTIBODIES FOR HYPERPHOSPHORILED TAUY AND ITS METHODS OF USE - Google Patents
SPECIFIC ANTIBODIES FOR HYPERPHOSPHORILED TAUY AND ITS METHODS OF USEInfo
- Publication number
- CR20190012A CR20190012A CR20190012A CR20190012A CR20190012A CR 20190012 A CR20190012 A CR 20190012A CR 20190012 A CR20190012 A CR 20190012A CR 20190012 A CR20190012 A CR 20190012A CR 20190012 A CR20190012 A CR 20190012A
- Authority
- CR
- Costa Rica
- Prior art keywords
- methods
- hyperphosphoriled
- tauy
- specific antibodies
- tau
- Prior art date
Links
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- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente invención se refiere a una clase de anticuerpo monoclonal que se une de manera específica al residuo fosforilado de serina 396 en la tau patológica hiperfosforilada (PHF) (pS396) con una afinidad mejorada, así como también a métodos de uso de estas moléculas y sus fragmentos de unión a tau en el tratamiento de la enfermedad de Alzheimer y otras tauopatías.The present invention relates to a class of monoclonal antibody that specifically binds to phosphorylated serine residue 396 in hyperphosphorylated pathological tau (PHF) (pS396) with improved affinity, as well as methods of using these molecules and its tau binding fragments in the treatment of Alzheimer's disease and other tauopathies.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA201600416 | 2016-07-12 | ||
DKPA201700005 | 2017-01-04 | ||
DKPA201700179 | 2017-03-14 | ||
PCT/EP2017/067067 WO2018011073A1 (en) | 2016-07-12 | 2017-07-07 | Antibodies specific for hyperphosphorylated tau and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CR20190012A true CR20190012A (en) | 2019-04-04 |
Family
ID=66592654
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR20190012A CR20190012A (en) | 2016-07-12 | 2017-07-07 | SPECIFIC ANTIBODIES FOR HYPERPHOSPHORILED TAUY AND ITS METHODS OF USE |
Country Status (1)
Country | Link |
---|---|
CR (1) | CR20190012A (en) |
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2017
- 2017-07-07 CR CR20190012A patent/CR20190012A/en unknown
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