AR109258A1 - SPECIFIC ANTIBODIES FOR HYPERPHOSPHORILED TAU AND ITS METHODS OF USE - Google Patents

SPECIFIC ANTIBODIES FOR HYPERPHOSPHORILED TAU AND ITS METHODS OF USE

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Publication number
AR109258A1
AR109258A1 ARP170101923A ARP170101923A AR109258A1 AR 109258 A1 AR109258 A1 AR 109258A1 AR P170101923 A ARP170101923 A AR P170101923A AR P170101923 A ARP170101923 A AR P170101923A AR 109258 A1 AR109258 A1 AR 109258A1
Authority
AR
Argentina
Prior art keywords
tau
methods
hyperphosphoriled
specific antibodies
tauopathies
Prior art date
Application number
ARP170101923A
Other languages
Spanish (es)
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck As filed Critical H Lundbeck As
Publication of AR109258A1 publication Critical patent/AR109258A1/en

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  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La presente acta se refiere a una clase de anticuerpo monoclonal que se une de manera específica al residuo fosforilado de serina 396 en la tau patológica hiperfosforilada (PHF) (pS396) con una afinidad mejorada, así como también a métodos de uso de estas moléculas y sus fragmentos de unión a tau en el tratamiento de la enfermedad de Alzheimer y otras tauopatías.This document refers to a class of monoclonal antibody that specifically binds phosphorylated serine residue 396 in hyperphosphorylated pathological tau (PHF) (pS396) with improved affinity, as well as methods of using these molecules and its tau binding fragments in the treatment of Alzheimer's disease and other tauopathies.

ARP170101923A 2016-07-12 2017-07-11 SPECIFIC ANTIBODIES FOR HYPERPHOSPHORILED TAU AND ITS METHODS OF USE AR109258A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA201600416 2016-07-12

Publications (1)

Publication Number Publication Date
AR109258A1 true AR109258A1 (en) 2018-11-14

Family

ID=64499905

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP170101923A AR109258A1 (en) 2016-07-12 2017-07-11 SPECIFIC ANTIBODIES FOR HYPERPHOSPHORILED TAU AND ITS METHODS OF USE

Country Status (1)

Country Link
AR (1) AR109258A1 (en)

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