CO6731129A2 - Process for the preparation of 4-amino-5-fluorine-3-halo-6- (substituted) picolinates - Google Patents

Process for the preparation of 4-amino-5-fluorine-3-halo-6- (substituted) picolinates

Info

Publication number
CO6731129A2
CO6731129A2 CO13175761A CO13175761A CO6731129A2 CO 6731129 A2 CO6731129 A2 CO 6731129A2 CO 13175761 A CO13175761 A CO 13175761A CO 13175761 A CO13175761 A CO 13175761A CO 6731129 A2 CO6731129 A2 CO 6731129A2
Authority
CO
Colombia
Prior art keywords
fluorine
picolinates
halo
amino
substituted
Prior art date
Application number
CO13175761A
Other languages
Spanish (es)
Inventor
Yuanming Zhu
Gregory T Whiteker
James M Renga
Kim E Arndt
Gary Alan Roth
David E Podhorez
Scott P West
Original Assignee
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc
Publication of CO6731129A2 publication Critical patent/CO6731129A2/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Los 4-amino-5-flúor-3-halo-6- (substituido) picolinatos son convenientemente preparados desde 4,5,6-tricloropicolinonitrilo mediante una serie de pasos que involucran al intercambio de flúor, la aminación, el intercambio de halógeno, la halogenación, la hidrólisis de nitrilo, la esterificación, y el acoplamiento de un metal de transición asistido.The 4-amino-5-fluorine-3-halo-6- (substituted) picolinates are conveniently prepared from 4,5,6-trichloropicolinonitrile by a series of steps involving fluorine exchange, amination, halogen exchange, halogenation, nitrile hydrolysis, esterification, and coupling of an assisted transition metal.

CO13175761A 2011-01-25 2013-07-25 Process for the preparation of 4-amino-5-fluorine-3-halo-6- (substituted) picolinates CO6731129A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161435936P 2011-01-25 2011-01-25

Publications (1)

Publication Number Publication Date
CO6731129A2 true CO6731129A2 (en) 2013-08-15

Family

ID=46544650

Family Applications (1)

Application Number Title Priority Date Filing Date
CO13175761A CO6731129A2 (en) 2011-01-25 2013-07-25 Process for the preparation of 4-amino-5-fluorine-3-halo-6- (substituted) picolinates

Country Status (20)

Country Link
US (2) US8754231B2 (en)
EP (1) EP2667712B1 (en)
JP (1) JP5781171B2 (en)
KR (2) KR20150013334A (en)
CN (1) CN103458689B (en)
AR (1) AR085020A1 (en)
AU (1) AU2012209281B2 (en)
BR (2) BR102012001643A2 (en)
CA (1) CA2825468C (en)
CO (1) CO6731129A2 (en)
HK (1) HK1188684A1 (en)
IL (1) IL227647B (en)
MX (1) MX338962B (en)
PL (1) PL2667712T3 (en)
RU (1) RU2542985C1 (en)
SG (1) SG192101A1 (en)
TW (1) TWI537252B (en)
UA (1) UA109806C2 (en)
WO (1) WO2012103045A1 (en)
ZA (1) ZA201305582B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2839627C (en) * 2011-06-30 2021-01-19 Dow Agrosciences Llc 3-alkoxy, thioalkyl and amino-4-amino-6-(substituted)picolinates and their use as herbicides
AR091856A1 (en) 2012-07-24 2015-03-04 Dow Agrosciences Llc PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUOR-3-HALO-6- (SUBSTITUTED) PICOLINATES
AR092355A1 (en) 2012-07-24 2015-04-15 Dow Agrosciences Llc FLUOROPICOLINOYL FLUORURES AND PROCESSES FOR THEIR PREPARATION
CN106977453A (en) * 2012-12-13 2017-07-25 美国陶氏益农公司 The method for preparing 4 amino, 5 fluorine 3 chlorine 6 (substituted) picolinic acid ester
BR102014028164A2 (en) * 2013-11-12 2015-09-08 Dow Agrosciences Llc process for fluorination of compounds
TW201609652A (en) 2013-11-12 2016-03-16 陶氏農業科學公司 Process for fluorinating compounds
TW201609651A (en) 2013-11-12 2016-03-16 陶氏農業科學公司 Process for fluorinating compounds
TWI726900B (en) 2015-08-04 2021-05-11 美商陶氏農業科學公司 Process for fluorinating compounds
ES2837035T3 (en) * 2016-07-07 2021-06-29 Dow Agrosciences Llc Procedures for the preparation of 4-alkoxy-3- (acyl or alkyl) oxypicolinamides
CN111655659B (en) * 2018-02-02 2023-03-28 关东电化工业株式会社 Method for producing compound having butadiene skeleton containing hydrogen and fluorine and/or chlorine
BR112021005140A8 (en) * 2018-09-19 2021-06-29 Corteva Agriscience Llc preparation of picloram halogen analogues
BR112022018513A2 (en) 2020-03-18 2022-11-01 Corteva Agriscience Llc IMPROVED SYNTHESIS OF 6-ARYL-4-AMINOPICOLINATES
BR112022018508A2 (en) 2020-03-18 2022-10-25 Corteva Agriscience Llc IMPROVED SYNTHESIS OF 4-AMINO-6-(HETEROCYCLIC)PICOLINATES

Family Cites Families (15)

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Publication number Priority date Publication date Assignee Title
US3285925A (en) * 1962-03-06 1966-11-15 Dow Chemical Co Amino-trichloropicolinic acid compounds
US3325272A (en) * 1965-06-23 1967-06-13 Dow Chemical Co Plant growth control methods and compositions
US3629424A (en) * 1967-12-26 1971-12-21 Dow Chemical Co Cyanofluoropyridines and fungicidal compositions and methods for using the same
US3803159A (en) 1967-12-26 1974-04-09 Dow Chemical Co Fluorine containing cyanopyridines
CN1042333C (en) * 1992-10-14 1999-03-03 美国氰胺公司 5,6-disubstituted-3-pyridiylmethyl ammonium halide compounds useful, for the preparation of 5-(substituted methyl)-2,3-pyridinedicarboxylic acids
FR2803592A1 (en) * 2000-01-06 2001-07-13 Aventis Cropscience Sa NOVEL DERIVATIVES OF 3-HYDROXYPICOLINIC ACID, PROCESS FOR THEIR PREPARATION AND FUNGICIDAL COMPOSITIONS CONTAINING SAME
AU760286B2 (en) * 2000-01-14 2003-05-08 Dow Agrosciences Llc 4-aminopicolinates and their use as herbicides
US6297197B1 (en) 2000-01-14 2001-10-02 Dow Agrosciences Llc 4-aminopicolinates and their use as herbicides
AR037228A1 (en) * 2001-07-30 2004-11-03 Dow Agrosciences Llc ACID COMPOUNDS 6- (ARIL OR HETEROARIL) -4-AMYNOPYCOLINIC, HERBICIDE COMPOSITION THAT UNDERSTANDS AND METHOD TO CONTROL UNWANTED VEGETATION
UA82358C2 (en) 2003-04-02 2008-04-10 Дау Агросайенсиз Ллс 6-alkyl or alkenyl-4-amionopicolinates, herbicidal composition, method for controlling undesirable vegetation
WO2006062979A1 (en) * 2004-12-06 2006-06-15 E.I. Dupont De Nemours And Company Herbicidal 6-cyclopropyl-substitute 4-aminopicolinic acid derivatives
KR101350071B1 (en) * 2006-01-13 2014-01-14 다우 아그로사이언시즈 엘엘씨 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides
DK2332914T3 (en) 2007-10-02 2013-06-17 Dow Agrosciences Llc Substituted 4-aminopicolinic acids and their use as herbicides
US8252938B2 (en) * 2009-06-08 2012-08-28 Dow Agrosciences, Llc. Process for the preparation of 6-(aryl)-4-aminopicolinates
GB0910766D0 (en) * 2009-06-22 2009-08-05 Syngenta Ltd Chemical compounds

Also Published As

Publication number Publication date
KR101537880B1 (en) 2015-07-17
TW201309648A (en) 2013-03-01
EP2667712B1 (en) 2016-08-31
US20120190859A1 (en) 2012-07-26
MX2013008602A (en) 2013-12-09
KR20150013334A (en) 2015-02-04
CN103458689A (en) 2013-12-18
HK1188684A1 (en) 2014-05-16
US20140206881A1 (en) 2014-07-24
EP2667712A1 (en) 2013-12-04
RU2013139379A (en) 2015-03-10
ZA201305582B (en) 2014-09-25
US8993772B2 (en) 2015-03-31
RU2542985C1 (en) 2015-02-27
UA109806C2 (en) 2015-10-12
KR20130121952A (en) 2013-11-06
AU2012209281B2 (en) 2015-06-25
BR112013018945A2 (en) 2017-05-02
JP5781171B2 (en) 2015-09-16
AR085020A1 (en) 2013-08-07
US8754231B2 (en) 2014-06-17
CN103458689B (en) 2015-09-23
EP2667712A4 (en) 2014-06-04
PL2667712T3 (en) 2017-06-30
TWI537252B (en) 2016-06-11
SG192101A1 (en) 2013-08-30
IL227647B (en) 2018-10-31
WO2012103045A1 (en) 2012-08-02
MX338962B (en) 2016-05-06
JP2014505073A (en) 2014-02-27
BR102012001643A2 (en) 2014-04-22
CA2825468C (en) 2016-08-23
CA2825468A1 (en) 2012-08-02
IL227647A0 (en) 2013-09-30

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