CO6290645A2 - Compuesto para el tratamiento de la hepatitis c - Google Patents
Compuesto para el tratamiento de la hepatitis cInfo
- Publication number
- CO6290645A2 CO6290645A2 CO10134256A CO10134256A CO6290645A2 CO 6290645 A2 CO6290645 A2 CO 6290645A2 CO 10134256 A CO10134256 A CO 10134256A CO 10134256 A CO10134256 A CO 10134256A CO 6290645 A2 CO6290645 A2 CO 6290645A2
- Authority
- CO
- Colombia
- Prior art keywords
- treatment
- hepatitis
- composite
- compounds
- hcv
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
Abstract
La invención comprende compuestos de fórmula I así como composiciones y procedimientos de uso de los compuestos. Los compuestos tienen actividad contra el virus de la hepatitis C (VHC) y son útiles en el tratamiento de aquellos infectados por VHC.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5074308P | 2008-05-06 | 2008-05-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO6290645A2 true CO6290645A2 (es) | 2011-06-20 |
Family
ID=40786514
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO10134256A CO6290645A2 (es) | 2008-05-06 | 2010-10-28 | Compuesto para el tratamiento de la hepatitis c |
Country Status (19)
Country | Link |
---|---|
US (1) | US8133884B2 (es) |
EP (1) | EP2280975B1 (es) |
JP (1) | JP2011520810A (es) |
KR (1) | KR20110015588A (es) |
CN (1) | CN102083834A (es) |
AR (1) | AR071684A1 (es) |
AU (1) | AU2009244409A1 (es) |
BR (1) | BRPI0915130A2 (es) |
CA (1) | CA2723683A1 (es) |
CL (1) | CL2009001089A1 (es) |
CO (1) | CO6290645A2 (es) |
EA (1) | EA201001748A1 (es) |
IL (1) | IL208753A0 (es) |
MX (1) | MX2010011921A (es) |
NZ (1) | NZ588556A (es) |
PE (1) | PE20091879A1 (es) |
TW (1) | TW200951135A (es) |
WO (1) | WO2009137454A1 (es) |
ZA (1) | ZA201007649B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070049593A1 (en) | 2004-02-24 | 2007-03-01 | Japan Tobacco Inc. | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor |
WO2009120650A1 (en) | 2008-03-27 | 2009-10-01 | Bristol-Myers Squibb Company | Aromatic heterocyclic fused indolobenzadiazepine hcv ns5b inhibitors |
UA103319C2 (en) | 2008-05-06 | 2013-10-10 | Глаксосмитклайн Ллк | Thiazole- and oxazole-benzene sulfonamide compounds |
CN103649079B (zh) | 2010-12-22 | 2016-11-16 | Abbvie公司 | 丙型肝炎抑制剂及其用途 |
WO2013030750A1 (en) | 2011-09-01 | 2013-03-07 | Lupin Limited | Antiviral compounds |
US9073943B2 (en) | 2012-02-10 | 2015-07-07 | Lupin Limited | Antiviral compounds with a dibenzooxaheterocycle moiety |
EA025391B1 (ru) * | 2012-07-18 | 2016-12-30 | Бристол-Майерс Сквибб Холдингс Айеленд | НОВЫЕ СПОСОБЫ И ПРОМЕЖУТОЧНЫЕ СОЕДИНЕНИЯ ДЛЯ ПОЛУЧЕНИЯ (4bS,5aR)-12-ЦИКЛОГЕКСИЛ-N-(N,N-ДИМЕТИЛСУЛЬФАМОИЛ)-3-МЕТОКСИ-5a-((1R,5S)-3-МЕТИЛ-3,8-ДИАЗАБИЦИКЛО[3.2.1]ОКТАН-8-КАРБОНИЛ)-4b,5,5a,6-ТЕТРАГИДРОБЕНЗО[3,4]ЦИКЛОПРОПА[5,6]АЗЕПИНО[1,2-a]ИНДОЛ-9-КАРБОКСАМИДА |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1719773E (pt) | 2004-02-24 | 2009-06-03 | Japan Tobacco Inc | Compostos heterotetracíclicos fundidos e a sua utilização como inibidores da polimerase do hcv |
US7153848B2 (en) | 2004-08-09 | 2006-12-26 | Bristol-Myers Squibb Company | Inhibitors of HCV replication |
MX2007004979A (es) | 2004-10-26 | 2007-06-14 | Angeletti P Ist Richerche Bio | Derivados de indol tetraciclicos como agentes antiviricos. |
GB0518390D0 (en) | 2005-09-09 | 2005-10-19 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
US7399758B2 (en) | 2005-09-12 | 2008-07-15 | Meanwell Nicholas A | Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors |
US7473688B2 (en) | 2005-09-13 | 2009-01-06 | Bristol-Myers Squibb Company | Indolobenzazepine HCV NS5B inhibitors |
US7456165B2 (en) | 2006-02-08 | 2008-11-25 | Bristol-Myers Squibb Company | HCV NS5B inhibitors |
GB0608928D0 (en) | 2006-05-08 | 2006-06-14 | Angeletti P Ist Richerche Bio | Therapeutic agents |
US7456166B2 (en) | 2006-05-17 | 2008-11-25 | Bristol-Myers Squibb Company | Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors |
US7521441B2 (en) | 2006-05-22 | 2009-04-21 | Bristol-Myers Squibb Company | Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors |
EP2029606B1 (en) | 2006-05-25 | 2010-05-26 | Brystol-Myers Squibb Company | Cyclopropyl fused indolobenzazepine hcv ns5b inhibitors |
WO2007140200A2 (en) | 2006-05-25 | 2007-12-06 | Bristol-Myers Squibb Company | Cyclopropyl fused indolobenzazepine hcv ns5b inhibitors |
US7452876B2 (en) | 2006-06-08 | 2008-11-18 | Bristol-Myers Squibb Company | Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors |
US7541351B2 (en) | 2007-01-11 | 2009-06-02 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
US7517872B2 (en) | 2007-02-22 | 2009-04-14 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
US7538102B2 (en) | 2007-03-14 | 2009-05-26 | Bristol-Myers Squibb Company | Compounds for the treatment of Hepatitis C |
US7547690B2 (en) | 2007-03-14 | 2009-06-16 | Bristol-Myers Squibb Company | Compounds for the treatment of Hepatitis C |
US7521444B2 (en) | 2007-03-14 | 2009-04-21 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
US7541353B2 (en) | 2007-03-14 | 2009-06-02 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
US7538103B2 (en) | 2007-03-15 | 2009-05-26 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
US20090018163A1 (en) | 2007-07-11 | 2009-01-15 | Bristol-Myers Squibb Company | Substituted Heterocyclic Ethers and Their Use in CNS Disorders |
US7642251B2 (en) | 2007-08-09 | 2010-01-05 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
US7652004B2 (en) | 2007-08-09 | 2010-01-26 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
US8129367B2 (en) | 2007-11-21 | 2012-03-06 | Bristol-Myers Squibb Company | Compounds for the treatment of Hepatitis C |
US8124601B2 (en) | 2007-11-21 | 2012-02-28 | Bristol-Myers Squibb Company | Compounds for the treatment of Hepatitis C |
-
2009
- 2009-05-04 US US12/434,748 patent/US8133884B2/en active Active
- 2009-05-05 AU AU2009244409A patent/AU2009244409A1/en not_active Abandoned
- 2009-05-05 CN CN2009801263266A patent/CN102083834A/zh active Pending
- 2009-05-05 MX MX2010011921A patent/MX2010011921A/es active IP Right Grant
- 2009-05-05 CA CA2723683A patent/CA2723683A1/en not_active Abandoned
- 2009-05-05 PE PE2009000605A patent/PE20091879A1/es not_active Application Discontinuation
- 2009-05-05 WO PCT/US2009/042805 patent/WO2009137454A1/en active Application Filing
- 2009-05-05 EA EA201001748A patent/EA201001748A1/ru unknown
- 2009-05-05 BR BRPI0915130A patent/BRPI0915130A2/pt not_active IP Right Cessation
- 2009-05-05 NZ NZ588556A patent/NZ588556A/en not_active IP Right Cessation
- 2009-05-05 JP JP2011508593A patent/JP2011520810A/ja not_active Withdrawn
- 2009-05-05 KR KR1020107027222A patent/KR20110015588A/ko not_active Application Discontinuation
- 2009-05-05 EP EP09743440.1A patent/EP2280975B1/en not_active Not-in-force
- 2009-05-06 CL CL2009001089A patent/CL2009001089A1/es unknown
- 2009-05-06 TW TW098115001A patent/TW200951135A/zh unknown
- 2009-05-06 AR ARP090101641A patent/AR071684A1/es not_active Application Discontinuation
-
2010
- 2010-10-14 IL IL208753A patent/IL208753A0/en unknown
- 2010-10-26 ZA ZA2010/07649A patent/ZA201007649B/en unknown
- 2010-10-28 CO CO10134256A patent/CO6290645A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP2280975A1 (en) | 2011-02-09 |
PE20091879A1 (es) | 2009-12-19 |
MX2010011921A (es) | 2010-11-30 |
AU2009244409A1 (en) | 2009-11-12 |
WO2009137454A1 (en) | 2009-11-12 |
EA201001748A1 (ru) | 2011-06-30 |
NZ588556A (en) | 2012-06-29 |
IL208753A0 (en) | 2010-12-30 |
EP2280975B1 (en) | 2014-01-01 |
CA2723683A1 (en) | 2009-11-12 |
ZA201007649B (en) | 2012-04-25 |
BRPI0915130A2 (pt) | 2019-09-24 |
US20090280083A1 (en) | 2009-11-12 |
TW200951135A (en) | 2009-12-16 |
KR20110015588A (ko) | 2011-02-16 |
CN102083834A (zh) | 2011-06-01 |
JP2011520810A (ja) | 2011-07-21 |
AR071684A1 (es) | 2010-07-07 |
CL2009001089A1 (es) | 2011-04-29 |
US8133884B2 (en) | 2012-03-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Application refused |