CO5280153A1 - ANTIGEN ASSOCIATED WITH TUMORS (R11) - Google Patents
ANTIGEN ASSOCIATED WITH TUMORS (R11)Info
- Publication number
- CO5280153A1 CO5280153A1 CO00058185A CO00058185A CO5280153A1 CO 5280153 A1 CO5280153 A1 CO 5280153A1 CO 00058185 A CO00058185 A CO 00058185A CO 00058185 A CO00058185 A CO 00058185A CO 5280153 A1 CO5280153 A1 CO 5280153A1
- Authority
- CO
- Colombia
- Prior art keywords
- antigen associated
- tumors
- seq
- fragment
- presents
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 239000000427 antigen Substances 0.000 title abstract 3
- 102000036639 antigens Human genes 0.000 title abstract 3
- 108091007433 antigens Proteins 0.000 title abstract 3
- 108020004414 DNA Proteins 0.000 abstract 2
- 102000053602 DNA Human genes 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Neurology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
1.- Molécula aislada de ADN que presenta la secuencia de nucleótidos representada en SEQ ID No. 1 o un polinucleótido, que se hibrida con esta molécula de ADN en condiciones rigurosas, o un fragmento de éste.4.- Antígeno asociado con tumores con la denominación R11-ORF-1, caracterizado porque presenta La secuencia de aminoácidos definida en SEQ ID NO: 2 o contiene a ésta como secuencio parcial.5.- Fragmento de proteína o péptido inmunógeno, caracterizado porque se deriva del antígeno asociado con un tumor, que se define en la reivindicación 4.1.- Isolated DNA molecule that presents the nucleotide sequence represented in SEQ ID No. 1 or a polynucleotide, which hybridizes with this DNA molecule under stringent conditions, or a fragment thereof.4.- Antigen associated with tumors with the designation R11-ORF-1, characterized in that it presents the amino acid sequence defined in SEQ ID NO: 2 or contains it as a partial sequence.5.- Fragment of immunogenic protein or peptide, characterized in that it is derived from the antigen associated with a tumor , which is defined in claim 4.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19936563A DE19936563A1 (en) | 1999-08-04 | 1999-08-04 | Tumor Associated Antigen |
Publications (1)
Publication Number | Publication Date |
---|---|
CO5280153A1 true CO5280153A1 (en) | 2003-05-30 |
Family
ID=7917065
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO00058185A CO5280153A1 (en) | 1999-08-04 | 2000-08-02 | ANTIGEN ASSOCIATED WITH TUMORS (R11) |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1206535A1 (en) |
JP (1) | JP2003506085A (en) |
AU (1) | AU6278300A (en) |
CA (1) | CA2383230A1 (en) |
CO (1) | CO5280153A1 (en) |
DE (1) | DE19936563A1 (en) |
MX (1) | MXPA02001137A (en) |
UY (1) | UY26266A1 (en) |
WO (1) | WO2001011040A1 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8258260B2 (en) | 1970-02-11 | 2012-09-04 | Immatics Biotechnologies Gmbh | Tumor-associated peptides binding promiscuously to human leukocyte antigen (HLA) class II molecules |
US8212000B2 (en) | 1970-02-11 | 2012-07-03 | Immatics Biotechnologies Gmbh | Tumor-associated peptides binding promiscuously to human leukocyte antigen (HLA) class II molecules |
US8211999B2 (en) | 1970-02-11 | 2012-07-03 | Immatics Biotechnologies Gmbh | Tumor-associated peptides binding promiscuously to human leukocyte antigen (HLA) class II molecules |
JP2003093066A (en) * | 2001-09-21 | 2003-04-02 | Univ Tokyo | Method for controlling proliferation and apoptosis of carcinoma cell |
WO2003063770A2 (en) | 2001-11-07 | 2003-08-07 | Mannkind Corporation | Expression vectors encoding epitopes of target-associated antigens and methods for their design |
DE10211088A1 (en) * | 2002-03-13 | 2003-09-25 | Ugur Sahin | Gene products differentially expressed in tumors and their use |
US20050221350A1 (en) | 2002-05-29 | 2005-10-06 | Toni Weinschenk | Method for identifying immunoreactive peptides |
DE10225144A1 (en) | 2002-05-29 | 2003-12-18 | Immatics Biotechnologies Gmbh | Tumor-associated peptides binding to MHC molecules |
DE10341812A1 (en) * | 2003-09-10 | 2005-04-07 | Ganymed Pharmaceuticals Ag | Differentially expressed in tumors gene products and their use |
DE102005041616B4 (en) * | 2005-09-01 | 2011-03-17 | Johannes-Gutenberg-Universität Mainz | Melanoma associated MHC class I associated oligopeptides and polynucleotides encoding them and their uses |
PT1760088E (en) | 2005-09-05 | 2008-05-14 | Immatics Biotechnologies Gmbh | Tumor-associated peptides binding promiscuously to human leukocyte antigen (hla) class ii molecules |
WO2010052244A1 (en) | 2008-11-05 | 2010-05-14 | Morphosys Ag | Deconvolution method |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69837273T2 (en) * | 1997-10-08 | 2008-01-31 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | HUMAN CANCER ANTIBODY NY ESO-1 / CAG-3 AND GENEAN CODING THEREFOR |
CA2383592A1 (en) * | 1999-03-31 | 2000-10-05 | Curagen Corporation | 2384891 acids including open reading frames encoding polypeptides; orfx |
-
1999
- 1999-08-04 DE DE19936563A patent/DE19936563A1/en not_active Withdrawn
-
2000
- 2000-07-28 MX MXPA02001137A patent/MXPA02001137A/en unknown
- 2000-07-28 JP JP2001515826A patent/JP2003506085A/en active Pending
- 2000-07-28 AU AU62783/00A patent/AU6278300A/en not_active Abandoned
- 2000-07-28 EP EP00949421A patent/EP1206535A1/en not_active Withdrawn
- 2000-07-28 CA CA002383230A patent/CA2383230A1/en not_active Abandoned
- 2000-07-28 WO PCT/EP2000/007338 patent/WO2001011040A1/en not_active Application Discontinuation
- 2000-08-02 CO CO00058185A patent/CO5280153A1/en not_active Application Discontinuation
- 2000-08-02 UY UY26266A patent/UY26266A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1206535A1 (en) | 2002-05-22 |
CA2383230A1 (en) | 2001-02-15 |
WO2001011040A1 (en) | 2001-02-15 |
JP2003506085A (en) | 2003-02-18 |
DE19936563A1 (en) | 2001-02-08 |
UY26266A1 (en) | 2001-01-31 |
MXPA02001137A (en) | 2002-11-04 |
AU6278300A (en) | 2001-03-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Application withdrawn |