CO5261579A1 - COMPOSITIONS FOR THE TOPICAL SUPPLY OF A PHARMACEUTICALLY ACTIVE AGENT THAT HAS REDUCED SKIN IRRITATION - Google Patents

COMPOSITIONS FOR THE TOPICAL SUPPLY OF A PHARMACEUTICALLY ACTIVE AGENT THAT HAS REDUCED SKIN IRRITATION

Info

Publication number
CO5261579A1
CO5261579A1 CO01010851A CO01010851A CO5261579A1 CO 5261579 A1 CO5261579 A1 CO 5261579A1 CO 01010851 A CO01010851 A CO 01010851A CO 01010851 A CO01010851 A CO 01010851A CO 5261579 A1 CO5261579 A1 CO 5261579A1
Authority
CO
Colombia
Prior art keywords
pharmaceutically active
compositions
alcohol
active agent
wax
Prior art date
Application number
CO01010851A
Other languages
Spanish (es)
Inventor
Paul Robert Tanner
Thomas Edward Huetter
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of CO5261579A1 publication Critical patent/CO5261579A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A61K8/553—Phospholipids, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/925—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/75—Anti-irritant

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se relaciona con una composición para el suministro tópico de por lo menos un agente farmacéuticamente activo que comprende:a) de 1% a 50% en peso de por lo menos un fosfolípido que se selecciona del grupo que consiste de fosfolípidos insaturados, fosfolípidos parcialmente saturados, y mezclas de éstos;b) de 0,1% a 50% en peso de por lo menos un agente acondicionador de la piel que se selecciona del grupo que consiste de petrolato, parafina líquida, cera de parafina, cera de abejas, espermaceti, cera microcristalina, alcohol cetílico, alcohol hexadecílico, alcohol estearílico, alcohol oleílico, miristato de isopropílico, palmitato de isopropilo, aceite vegetal, escualeno, escualano, ácido palmítico, ácido esteárico, pamitato de cetilo, lanolina, tocoferol, acetato de tocoferol, glicerina, hexilenglicol, propilenglicol, sorbitol, pantenol, polialcoholes que tienen 3-5 átomos de carbono, ymezclas de estos;c) de 0,01% a 10% de por lo menos un agente farmacéuticamente activo;d) por lo menos un material portador adecuado que se selecciona de componentes que se utilizan en composiciones para aplicación tópica.The present invention relates to a composition for the topical delivery of at least one pharmaceutically active agent comprising: a) from 1% to 50% by weight of at least one phospholipid which is selected from the group consisting of unsaturated phospholipids, partially saturated phospholipids, and mixtures thereof; b) from 0.1% to 50% by weight of at least one skin conditioning agent that is selected from the group consisting of petrolatum, liquid paraffin, paraffin wax, wax bees, spermaceti, microcrystalline wax, cetyl alcohol, hexadecyl alcohol, stearyl alcohol, oleyl alcohol, isopropyl myristate, isopropyl palmitate, vegetable oil, squalene, squalane, palmitic acid, stearic acid, cetyl pamitate, lanolin, tocopherol, acetate tocopherol, glycerin, hexylene glycol, propylene glycol, sorbitol, panthenol, polyalcohols having 3-5 carbon atoms, and mixtures thereof; c) from 0.01% to 10% of at least one agent and pharmaceutically active; d) at least one suitable carrier material that is selected from components that are used in compositions for topical application.

CO01010851A 2000-02-14 2001-02-13 COMPOSITIONS FOR THE TOPICAL SUPPLY OF A PHARMACEUTICALLY ACTIVE AGENT THAT HAS REDUCED SKIN IRRITATION CO5261579A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50316800A 2000-02-14 2000-02-14
US50356800A 2000-02-14 2000-02-14

Publications (1)

Publication Number Publication Date
CO5261579A1 true CO5261579A1 (en) 2003-03-31

Family

ID=27054407

Family Applications (1)

Application Number Title Priority Date Filing Date
CO01010851A CO5261579A1 (en) 2000-02-14 2001-02-13 COMPOSITIONS FOR THE TOPICAL SUPPLY OF A PHARMACEUTICALLY ACTIVE AGENT THAT HAS REDUCED SKIN IRRITATION

Country Status (4)

Country Link
AU (1) AU2001236996A1 (en)
CO (1) CO5261579A1 (en)
PE (1) PE20011092A1 (en)
WO (1) WO2001060336A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020119173A1 (en) * 2000-12-22 2002-08-29 Lin Samuel Qcheng Cosmetic compositions for preventing skin irritation
GB0704846D0 (en) * 2007-03-13 2007-04-18 Futura Medical Dev Ltd Topical pharmaceutical formulation
PL214538B1 (en) * 2009-05-28 2013-08-30 P P F Hasco Lek Spolka Akcyjna Liposome composition containing naproxen and a method for production of liposome composition containing naproxen
CN113648278A (en) * 2013-05-03 2021-11-16 立普妥公司 Vehicle and topical composition for administration

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4937078A (en) * 1988-08-26 1990-06-26 Mezei Associates Limited Liposomal local anesthetic and analgesic products
DE4021084C1 (en) * 1990-07-03 1991-11-21 Hans Dr. 5024 Pulheim De Lautenschlaeger Fumarate topical compsn. contg. liposome(s) improving bio-availability - esp. for treating psoriasis, contain liposomal structure, alcohol, stabiliser and fumaric acid (deriv.) and are stable and non irritant
US5766628A (en) * 1992-02-24 1998-06-16 Merz + Co. Gmbh & Co. Bath and shower composition having vesicle-forming properties and method for the production and use thereof
ES2136105T3 (en) * 1992-08-04 1999-11-16 Rhone Poulenc Rorer Gmbh PHARMACEUTICAL AND / OR COSMETIC PREPARATION.
US5945409A (en) * 1995-03-10 1999-08-31 Wilson T. Crandall Topical moisturizing composition and method

Also Published As

Publication number Publication date
WO2001060336A1 (en) 2001-08-23
PE20011092A1 (en) 2001-11-12
AU2001236996A1 (en) 2001-08-27

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Legal Events

Date Code Title Description
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