CO5261532A1 - silylated heterocyclic compounds, processes for the preparation thereof and pharmaceutical composition containing them - Google Patents

silylated heterocyclic compounds, processes for the preparation thereof and pharmaceutical composition containing them

Info

Publication number
CO5261532A1
CO5261532A1 CO00084393A CO00084393A CO5261532A1 CO 5261532 A1 CO5261532 A1 CO 5261532A1 CO 00084393 A CO00084393 A CO 00084393A CO 00084393 A CO00084393 A CO 00084393A CO 5261532 A1 CO5261532 A1 CO 5261532A1
Authority
CO
Colombia
Prior art keywords
carbon atoms
pharmaceutical composition
composition containing
processes
preparation
Prior art date
Application number
CO00084393A
Other languages
Spanish (es)
Inventor
Joachim Mozulak
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE19954847 priority Critical
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CO5261532A1 publication Critical patent/CO5261532A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • C07F7/0814Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring said ring is substituted at a C ring atom by Si

Abstract

La presente invención se relaciona con un compuesto de la fórmula I:<EMI FILE="00084393_1" ID="1" IMF=JPEG >en donde X es CH2 u O, R1 es hidrógeno, alquilo (de 1 a 4 átomos de carbono), alquenilo (de 3 a 5 átomos de carbono) en donde el doble enlace no está adyacente al átomo de nitrógeno, o bencilo, R2 es hidroxilo o alcoxilo (de 1 a 4 átomos de carbono), y R3, R4, y R5, son independientemente alquilo (de 1 a 4 átomos de carbono), en forma de base libre o de sal de adición de ácido. The present invention relates to a compound of formula I: <EMI FILE = "00084393_1" ID = "1" MFI = JPEG> wherein X is CH2 or O, R1 is hydrogen, alkyl (of 1 to 4 carbon atoms ), alkenyl (3 to 5 carbon atoms) wherein the double bond is not adjacent to the nitrogen atom, or benzyl, R2 is hydroxy or alkoxy (of 1 to 4 carbon atoms), and R3, R4, and R5 they are independently alkyl (of 1 to 4 carbon atoms), in free base or acid addition salt. Igualmente, se refiere al proceso para la preparación de dicho compuesto ya una composición farmacéutica que lo contiene. Also it refers to the process for preparing said compound and a pharmaceutical composition containing it.
CO00084393A 1999-11-15 2000-11-07 silylated heterocyclic compounds, processes for the preparation thereof and pharmaceutical composition containing them CO5261532A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19954847 1999-11-15

Publications (1)

Publication Number Publication Date
CO5261532A1 true CO5261532A1 (en) 2003-03-31

Family

ID=7929072

Family Applications (1)

Application Number Title Priority Date Filing Date
CO00084393A CO5261532A1 (en) 1999-11-15 2000-11-07 silylated heterocyclic compounds, processes for the preparation thereof and pharmaceutical composition containing them

Country Status (6)

Country Link
AR (1) AR026451A1 (en)
AU (1) AU2356301A (en)
CO (1) CO5261532A1 (en)
EC (1) ECSP003761A (en)
PE (1) PE10232001A1 (en)
WO (1) WO2001036428A1 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2689892A1 (en) * 1992-04-09 1993-10-15 Rhone Poulenc Rorer Sa New 4-substd. 1,4-di:phenyl-1-sila:cyclopentane derivs. - used as serotonin antagonists e.g. for treating anxiety, migraine, asthma or hypertension
US6210705B1 (en) * 1997-12-15 2001-04-03 Noven Pharmaceuticals, Nc. Compositions and methods for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate

Also Published As

Publication number Publication date
AU2356301A (en) 2001-05-30
PE10232001A1 (en) 2001-09-27
ECSP003761A (en) 2002-06-26
WO2001036428A1 (en) 2001-05-25
AR026451A1 (en) 2003-02-12

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Legal Events

Date Code Title Description
FA Application withdrawn