CO5251417A1 - Inhibidor de mataloproteasa acido aromatico sulfohidroxamico - Google Patents

Inhibidor de mataloproteasa acido aromatico sulfohidroxamico

Info

Publication number
CO5251417A1
CO5251417A1 CO00035030A CO00035030A CO5251417A1 CO 5251417 A1 CO5251417 A1 CO 5251417A1 CO 00035030 A CO00035030 A CO 00035030A CO 00035030 A CO00035030 A CO 00035030A CO 5251417 A1 CO5251417 A1 CO 5251417A1
Authority
CO
Colombia
Prior art keywords
mmp
aromatic
mataloprotease
sulfohydroxamic
acima
Prior art date
Application number
CO00035030A
Other languages
English (en)
Inventor
Thomas E Barta
Daniel P Becker
Louis J Bedell
Terri L Boehm
Jeffrey N Carroll
Gary A Decrescenzo
M Fobian Yvette
John N Freskos
Daniel P Getman
Joseph J Mcdonald
Susan L Hockerman
Susan C Howard
Stephen A Kolodziej
H Li Madeleine
Deborah A Mischke
Joseph G Rico
W Stehle Nathan
Michael B Tollefson
William F Vernier
Clara I Villamil
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of CO5251417A1 publication Critical patent/CO5251417A1/es

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Un proceso de tratamiento de un mamífero huésped que presenta una condición asociada con actividad patológica de la metaloproteasa matriz de una cantidad efectiva de un ácido sulfon-hidroxámico aromático que presenta una excelente actividad inhibitoria de una o más de las encimas de la metaloproteasa matriz (MMP), tales como MMP-2, MMP-9 y MMP-13, mientras que presenta una actividad inhibitoria sustancialmente menor al menos contra la MMP-1. <EMI FILE="00035030_1" ID="1" IMF=JPEG >
CO00035030A 1999-05-14 2000-05-15 Inhibidor de mataloproteasa acido aromatico sulfohidroxamico CO5251417A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31183799A 1999-05-14 1999-05-14

Publications (1)

Publication Number Publication Date
CO5251417A1 true CO5251417A1 (es) 2003-02-28

Family

ID=27757522

Family Applications (1)

Application Number Title Priority Date Filing Date
CO00035030A CO5251417A1 (es) 1999-05-14 2000-05-15 Inhibidor de mataloproteasa acido aromatico sulfohidroxamico

Country Status (5)

Country Link
AR (1) AR035547A1 (es)
CO (1) CO5251417A1 (es)
PE (1) PE20010202A1 (es)
UY (1) UY26145A1 (es)
ZA (1) ZA200109006B (es)

Also Published As

Publication number Publication date
AR035547A1 (es) 2004-06-16
ZA200109006B (en) 2002-12-02
PE20010202A1 (es) 2001-02-19
UY26145A1 (es) 2000-12-29

Similar Documents

Publication Publication Date Title
BR0010562A (pt) Inibidor de metaloprotease do ácido hidrox mico de sulfona aromática
EP1022334A3 (en) Novel amylases
DE69828783D1 (de) Hydroxamsäure-sulfonamid-derivate mit amidiertem aromatischen ring
TR200103493T2 (tr) Metaloproteaz önleyicileri
JO2283B1 (en) Pyrimidinyl-N-Acyl-L-Phenyl Anines
ATE254599T1 (de) Divalente sulfonyl-aryl-oder heteroaryl hydroxamsäureverbindungen
AP2001002240A0 (en) Sufamato hydroxamic acid metalloprotease inhibitor.
NO983688L (no) Serin-protease-inhibitorer
EP0931788A3 (en) Metalloprotease inhibitors
CA2208018A1 (en) Sulfonamides
ATE297188T1 (de) Stabilisierte ascorbinsäure-lösungen
HK1059439A1 (en) Compounds having activity as inhibitors of cytochrome p450rai
NO20013675D0 (no) 2,3,4,5-Tetrahydro-1H-[1,4)benzodiazepin-3-hydroksamsyre som matriks-metalloproteinaseinhibitorer
NZ515197A (en) Hydroxamic acid derivatives useful as matrix metalloprotease inhibitors
CA2266759A1 (en) 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase
AR024470A1 (es) Dispositivo para procesamiento de datos y el correspondiente metodo
BR9907746A (pt) ácidos 2,3,4,5-tetraidro-1h[1,4]-benzodiazepina-3-hidroxâmic os como inibidores de matriz de metaloproteinase
DK1204659T3 (da) Serotonerge benzofuraner
CO5251417A1 (es) Inhibidor de mataloproteasa acido aromatico sulfohidroxamico
NZ516620A (en) 1,4-substituted 4,4-diaryl cyclohexanes
DK1244643T3 (da) Tryptaseinhibitorer
DK1244614T3 (da) Tryptase-inhibitorer
ATE238062T1 (de) Hemmung von hiv-infektion
AR016514A1 (es) Composicion para mejorar el malestar estomacal, metodo para preparar dicha composicion y metodo para utilizarla
FR2784582B3 (fr) Nouvelle utilisation therapeutique de composes a activite beta-3-agoniste

Legal Events

Date Code Title Description
FC Application refused