CO5241271A1 - PIRAZOL [3,4-d] PIRIMIDINE COMPOUNDS THAT HAVE AFFINITY FOR ADENOSINE RECEPTORS, HAVE ANTI-CONVERSION AND ANTI-ALLERGIC / ANTIASMATIC EFFECT AND PROCEDURES FOR THE PREPARATION OF THESE - Google Patents

PIRAZOL [3,4-d] PIRIMIDINE COMPOUNDS THAT HAVE AFFINITY FOR ADENOSINE RECEPTORS, HAVE ANTI-CONVERSION AND ANTI-ALLERGIC / ANTIASMATIC EFFECT AND PROCEDURES FOR THE PREPARATION OF THESE

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Publication number
CO5241271A1
CO5241271A1 CO99038263A CO99038263A CO5241271A1 CO 5241271 A1 CO5241271 A1 CO 5241271A1 CO 99038263 A CO99038263 A CO 99038263A CO 99038263 A CO99038263 A CO 99038263A CO 5241271 A1 CO5241271 A1 CO 5241271A1
Authority
CO
Colombia
Prior art keywords
antiasmatic
pirazol
compounds
allergic
affinity
Prior art date
Application number
CO99038263A
Other languages
Spanish (es)
Inventor
Thomas Arnold
Lankau Hans Joachim
Menser Manfred
Angelika Rostock
Christine Tober
Unverferth Klaus
Original Assignee
Dresden Arzneimittel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19827679A external-priority patent/DE19827679A1/en
Application filed by Dresden Arzneimittel filed Critical Dresden Arzneimittel
Publication of CO5241271A1 publication Critical patent/CO5241271A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Compuestos de pirazol [3,4-d] pirimidinas caracterizados porque tienen nuevos compuestos de fòrmula general 1<EMI FILE="99038263_1" ID="1" IMF=JPEG >o sus tautòmeros, dondeX significa oxìgeno o azufre e Y significa halògeno, C1-C4-alquilo, C1-C4-alcoxi, trifluormetilo o trifluormetoxi.Procedimiento para elaborar los compuestos de pirazol [3,4-d] piramiditas de fòrmula ( I ) segùn la reivindicación 1, donde X es oxìgeno, caracterizado porque se cicliza un compuesto de fòrmula 2 con formamida.<EMI FILE="99038263_2" ID="2" IMF=JPEG >Donde Z significa hidroxi, alcoxi o aminoe Y significa halògeno, C1-C4-alquilo, C1-C4-alcoxi, trifluorometilo o trifluorometoxi.Pyrazole [3,4-d] pyrimidine compounds characterized in that they have new compounds of general formula 1 <EMI FILE = "99038263_1" ID = "1" IMF = JPEG> or their tautomeres, where X means oxygen or sulfur and Y means halogen, C1-C4-alkyl, C1-C4-alkoxy, trifluoromethyl or trifluoromethoxy.Procedure for making the pyrazole [3,4-d] pyramidal compounds of formula (I) according to claim 1, wherein X is oxygen, characterized in that it is cyclized a compound of formula 2 with formamide. <EMI FILE = "99038263_2" ID = "2" IMF = JPEG> Where Z means hydroxy, alkoxy or aminoe Y means halogen, C1-C4-alkyl, C1-C4-alkoxy, trifluoromethyl or trifluoromethoxy.

CO99038263A 1998-06-22 1999-06-18 PIRAZOL [3,4-d] PIRIMIDINE COMPOUNDS THAT HAVE AFFINITY FOR ADENOSINE RECEPTORS, HAVE ANTI-CONVERSION AND ANTI-ALLERGIC / ANTIASMATIC EFFECT AND PROCEDURES FOR THE PREPARATION OF THESE CO5241271A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19827679A DE19827679A1 (en) 1998-06-22 1998-06-22 New pyrazolo(3,4-d)pyrimidine derivative adenosine A3 receptor antagonists, used for treating epilepsy, asthma or allergy

Publications (1)

Publication Number Publication Date
CO5241271A1 true CO5241271A1 (en) 2003-01-31

Family

ID=40956502

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99038263A CO5241271A1 (en) 1998-06-22 1999-06-18 PIRAZOL [3,4-d] PIRIMIDINE COMPOUNDS THAT HAVE AFFINITY FOR ADENOSINE RECEPTORS, HAVE ANTI-CONVERSION AND ANTI-ALLERGIC / ANTIASMATIC EFFECT AND PROCEDURES FOR THE PREPARATION OF THESE

Country Status (3)

Country Link
KR (1) KR100350823B1 (en)
AR (1) AR018908A1 (en)
CO (1) CO5241271A1 (en)

Also Published As

Publication number Publication date
KR20010023124A (en) 2001-03-26
KR100350823B1 (en) 2002-08-29
AR018908A1 (en) 2001-12-12

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