CO5231233A1 - PROCESS FOR RECOVERING ANTIBIOTICS OLIGOSACARIDS LIPOFILIC LIPOFILICOS - Google Patents

PROCESS FOR RECOVERING ANTIBIOTICS OLIGOSACARIDS LIPOFILIC LIPOFILICOS

Info

Publication number
CO5231233A1
CO5231233A1 CO99078839A CO99078839A CO5231233A1 CO 5231233 A1 CO5231233 A1 CO 5231233A1 CO 99078839 A CO99078839 A CO 99078839A CO 99078839 A CO99078839 A CO 99078839A CO 5231233 A1 CO5231233 A1 CO 5231233A1
Authority
CO
Colombia
Prior art keywords
antibiotic
broth
absorbent
absorbed
oligosacarids
Prior art date
Application number
CO99078839A
Other languages
Spanish (es)
Inventor
Alroy Yair
Steven Blaisdell
Allan Morenberg
Eugene Schaefer
Original Assignee
Cherinf Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cherinf Corp filed Critical Cherinf Corp
Publication of CO5231233A1 publication Critical patent/CO5231233A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Un proceso para recuperar un antibiótico oligodacárido lipofílico a partir de un caldo de fermentación acuosa que contiene al antibiótico oligosacárido lipofílico mezclado con impurezas, derivados y/o sólidos suspendidos, que comprende:a) combinar dicho caldo de fermentación con un absorbente; b) ajustar el pH del caldo a alcalino a fin de solubilizar el antibiótico en el caldo;c) dar tiempo suficiente para que el antibiótico solubilizado en el caldo alcalino sea absorbido por el absorbente;d) ajustar el pH del caldo a casi neutral a fin de estabilizar el antibiótico absorbido en el absorbente; ye) separar el absorbente en el cual el antibiótico es absorbido a partir del caldo.También se revela un medio para almacenar un antibiótico oligosacárido que comprende un absorbente que tiene un antibiótico oligosacárido lipofilico absorbido en el mismo.A process for recovering a lipophilic oligodaccharide antibiotic from an aqueous fermentation broth containing the lipophilic oligosaccharide antibiotic mixed with impurities, derivatives and / or suspended solids, comprising: a) combining said fermentation broth with an absorbent; b) adjust the pH of the broth to alkaline in order to solubilize the antibiotic in the broth; c) allow sufficient time for the antibiotic solubilized in the alkaline broth to be absorbed by the absorbent; d) adjust the pH of the broth to almost neutral to in order to stabilize the absorbed antibiotic in the absorbent; and e) separating the absorbent in which the antibiotic is absorbed from the broth. A means for storing an oligosaccharide antibiotic comprising an absorbent having a lipophilic oligosaccharide antibiotic absorbed therein is also disclosed.

CO99078839A 1998-12-18 1999-12-16 PROCESS FOR RECOVERING ANTIBIOTICS OLIGOSACARIDS LIPOFILIC LIPOFILICOS CO5231233A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21568998A 1998-12-18 1998-12-18

Publications (1)

Publication Number Publication Date
CO5231233A1 true CO5231233A1 (en) 2002-12-27

Family

ID=22803963

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99078839A CO5231233A1 (en) 1998-12-18 1999-12-16 PROCESS FOR RECOVERING ANTIBIOTICS OLIGOSACARIDS LIPOFILIC LIPOFILICOS

Country Status (5)

Country Link
AR (1) AR021717A1 (en)
AU (1) AU2157200A (en)
CO (1) CO5231233A1 (en)
PE (1) PE20001370A1 (en)
WO (1) WO2000037670A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200812687A (en) * 2006-07-10 2008-03-16 Sicor Inc Apparatus for the separation of a resin from a reaction mixture

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1173368B (en) * 1984-02-24 1987-06-24 Zambon Spa PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE ALFA-ARILALCANOIC ACIDS
US4735903A (en) * 1984-06-21 1988-04-05 Schering Corporation Micromonospora carbonacea var africana
ZA927923B (en) * 1991-10-16 1993-04-26 Schering Corp Lipophilic oligosaccharide antibiotic salt compositions.
US5763600A (en) * 1997-04-18 1998-06-09 Schering Corporation Oligosaccharide antibiotics and process for preparation thereof

Also Published As

Publication number Publication date
AU2157200A (en) 2000-07-12
AR021717A1 (en) 2002-07-31
WO2000037670A1 (en) 2000-06-29
PE20001370A1 (en) 2000-12-09

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Legal Events

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