CO5221105A1 - TOPICAL FORMULATIONS WITH IMPROVED ABSORPTION CONTAINING SPINOSAD, MIRISTATO DE ISOPROPILO AND A MISCIBILIZING AGENT - Google Patents

TOPICAL FORMULATIONS WITH IMPROVED ABSORPTION CONTAINING SPINOSAD, MIRISTATO DE ISOPROPILO AND A MISCIBILIZING AGENT

Info

Publication number
CO5221105A1
CO5221105A1 CO00059536A CO00059536A CO5221105A1 CO 5221105 A1 CO5221105 A1 CO 5221105A1 CO 00059536 A CO00059536 A CO 00059536A CO 00059536 A CO00059536 A CO 00059536A CO 5221105 A1 CO5221105 A1 CO 5221105A1
Authority
CO
Colombia
Prior art keywords
formulation
agent
ectoparasiticide
isopropilo
miristato
Prior art date
Application number
CO00059536A
Other languages
Spanish (es)
Inventor
Kassebaum James Web
Paul Thomas Pugh
William Webster Thompson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CO5221105A1 publication Critical patent/CO5221105A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Una formulación tópica ectoparasiticida que contengan entre aproximadamente 0.1 a aproximadamente 25 por ciento en peso de un ectoparasiticida, entre aproximadamente 25 a aproximadamente 99.9 por ciento en peso de un alcanoato (C10-C20) alquilo (C3-C6) ramificado como agente esparsor, y opcionalmente hasta aproximadamente un 70% de una agente miscibilizante compatible con sistemas de solvente orgánico. Una formulación de la reivindicación 1 donde el agente esparsor es un alcanoato (C12 - C16) alquilo (C3 - C6) ramificado.Una formulación de la reivindicación 2 donde el alcanoato (C10 - C20) aIquilo (C3 - C6) ramificado es miristato de isopropilo.Una formulación de las reivindicaciones 1, 2 ó 3 donde el ectoparasiticida es una espinosina o un derivado o sal del mismo fisiológicamente aceptable.Una formulación de las reivindicaciones 1, 2 ó 3 donde el ectoparasiticida es ciperpiretrina.Una formulación de las reivindicaciones 1, 2, 3 ,4 ó 5 que además contenga un agente miscibilizante seleccionado entre ácidos fórmico, acético, propiónico, benzóico, butírico, valérico, capróico, benzóico, enántico, caprílico, pelargónico, cáprico, undecílico.A topical ectoparasiticide formulation containing between about 0.1 to about 25 percent by weight of an ectoparasiticide, between about 25 to about 99.9 percent by weight of a (C10-C20) alkyl (C3-C6) alkanoate branched as a spacing agent, and optionally up to about 70% of a miscibilizing agent compatible with organic solvent systems. A formulation of claim 1 wherein the spacer agent is a branched (C12-C16) alkanoate (C3-C6) alkyl.A formulation of claim 2 wherein the branched (C10-C20) alkanoate (C3-C6) alkyl is myristate of isopropyl.A formulation of claims 1, 2 or 3 wherein the ectoparasiticide is a spinosyne or a physiologically acceptable derivative or salt thereof.A formulation of claims 1, 2 or 3 wherein the ectoparasiticide is cyperpyrethrin.A formulation of claims 1 , 2, 3, 4 or 5 which also contains a miscibilizing agent selected from formic, acetic, propionic, benzoic, butyric, valeric, capric, benzoic, enantic, caprilic, pelargonic, capric, undecyl acids.

CO00059536A 1999-08-12 2000-08-09 TOPICAL FORMULATIONS WITH IMPROVED ABSORPTION CONTAINING SPINOSAD, MIRISTATO DE ISOPROPILO AND A MISCIBILIZING AGENT CO5221105A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14850899P 1999-08-12 1999-08-12

Publications (1)

Publication Number Publication Date
CO5221105A1 true CO5221105A1 (en) 2002-11-28

Family

ID=22526069

Family Applications (1)

Application Number Title Priority Date Filing Date
CO00059536A CO5221105A1 (en) 1999-08-12 2000-08-09 TOPICAL FORMULATIONS WITH IMPROVED ABSORPTION CONTAINING SPINOSAD, MIRISTATO DE ISOPROPILO AND A MISCIBILIZING AGENT

Country Status (17)

Country Link
EP (1) EP1207851A1 (en)
JP (1) JP2003520779A (en)
AR (1) AR025234A1 (en)
AU (1) AU770542B2 (en)
BR (1) BR0013245A (en)
CA (1) CA2380643A1 (en)
CO (1) CO5221105A1 (en)
HU (1) HUP0202823A2 (en)
IL (2) IL147829A0 (en)
MX (1) MXPA02001502A (en)
MY (1) MY128816A (en)
NO (1) NO20020685L (en)
NZ (1) NZ516781A (en)
PE (1) PE20010359A1 (en)
SV (1) SV2002000143A (en)
TW (1) TWI236376B (en)
WO (1) WO2001012156A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6933318B1 (en) 1999-08-12 2005-08-23 Eli Lilly And Company Topical organic ectoparasiticidal formulations
PT1207756E (en) 1999-08-12 2006-07-31 Lilly Co Eli USE OF ESPINOSADE OR A FORMULATION THAT INCLUDES ESPINOSADE
US6927210B1 (en) 1999-08-12 2005-08-09 Eli Lilly And Company Ectoparasiticidal aqueous suspension formulations of spinosyns
AUPQ441699A0 (en) 1999-12-02 2000-01-06 Eli Lilly And Company Pour-on formulations
US6727228B2 (en) * 2001-04-25 2004-04-27 Johnson & Johnson Consumer Companies, Inc. Pediculicidal and ovacidal treatment compositions and methods for killing head lice and their eggs
DK1435786T3 (en) 2001-09-17 2011-10-03 Lilly Co Eli Pesticidal formulations
US6663876B2 (en) * 2002-04-29 2003-12-16 Piedmont Pharmaceuticals, Llc Methods and compositions for treating ectoparasite infestation
US8007820B2 (en) 2005-09-16 2011-08-30 W. Neudorff Gmbh Kg Wide spectrum insecticide and miticide composition
KR101404913B1 (en) 2006-05-25 2014-06-09 다우 아그로사이언시즈 엘엘씨 Spinosyn fumigants
WO2007144786A2 (en) * 2006-05-26 2007-12-21 Entarco Sa The vapor-phase application of spinosyn for the control of pests, and formulations and products utilizing the same
EP2248422A1 (en) * 2009-05-08 2010-11-10 Novartis AG Ectoparasiticidal compositions
TWI510189B (en) * 2009-06-19 2015-12-01 Lilly Co Eli Ectoparasiticidal methods and formulations
US8697661B2 (en) 2009-06-24 2014-04-15 Christine Kritikou Use of spinosyns and spinosyn compositions against herpesviridae viral infections
CA2885964C (en) 2012-11-14 2017-09-26 Eli Lilly And Company Ectoparasiticidal methods and formulations comprising spinetoram, benzyl alcohol and propylene carbonate
JP2022502398A (en) 2018-09-27 2022-01-11 ０９０３６０８ ビー シー リミテッド Method for delivering synergistic extermination composition and insecticidal active ingredient

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3125897A1 (en) * 1981-07-01 1983-02-10 Bayer Ag, 5090 Leverkusen EECTOPARASITICIDAL SPRAY FORMULATIONS
DE3317823A1 (en) * 1983-05-17 1984-11-22 Bayer Ag, 5090 Leverkusen PEST CONTROL
CO5210925A1 (en) * 1998-11-17 2002-10-30 Novartis Ag TETRASUSTITUID DIAMINUM NITROGUANIDINE DERIVATIVES

Also Published As

Publication number Publication date
IL147829A (en) 2006-08-20
EP1207851A1 (en) 2002-05-29
IL147829A0 (en) 2002-08-14
PE20010359A1 (en) 2001-04-03
BR0013245A (en) 2002-04-16
NZ516781A (en) 2003-03-28
NO20020685D0 (en) 2002-02-11
HUP0202823A2 (en) 2003-03-28
CA2380643A1 (en) 2001-02-22
AR025234A1 (en) 2002-11-13
AU6220600A (en) 2001-03-13
JP2003520779A (en) 2003-07-08
WO2001012156A1 (en) 2001-02-22
MY128816A (en) 2007-02-28
NO20020685L (en) 2002-04-09
AU770542B2 (en) 2004-02-26
MXPA02001502A (en) 2002-07-02
SV2002000143A (en) 2002-02-05
TWI236376B (en) 2005-07-21

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